Publications by authors named "Yuya Hirose"
Article Synopsis
- The COVID-19 pandemic has driven the search for new antiviral treatments targeting SARS-CoV-2, specifically the 3C-like protease (3CL).
- Researchers developed a new class of covalent inhibitors using chlorofluoroacetamide (CFA) that effectively block the replication of the virus.
- One specific compound demonstrated strong antiviral activity and favorable properties, indicating its potential as a lead candidate for COVID-19 treatment.
b-Series gangliosides are abundant in central nervous tissues and are involved in important nerve processes. However, their functions are complicated because of their properties of forming dynamic domains in cell plasma membranes (PMs), called lipid rafts. In this study, we aim to develop fluorescently labeled b-series gangliosides that are useful for single-molecule imaging.
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