A novel regulation on the developmental checkpoint protein Sda that controls sporulation and biofilm formation in .

Unlabelled: Biofilm formation by is triggered by an unusually simple environmental sensing mechanism. Certain serine codons, the four TCN codons (N for A, T, C, or G), in the gene for the biofilm repressor SinR caused lowered SinR translation and subsequent biofilm induction during transition from exponential to stationary growth. Global ribosome profiling showed that ribosomes pause when translating the four UCN (U for T on the mRNA) serine codons on mRNA, but not the two AGC/AGU serine codons.

Parasomnias in Post-Secondary Students: Prevalence, Distress, and Coping Strategies.

Parasomnias are a group of sleep disorders characterized by abnormal and unpleasant motor, verbal, or behavioral events that occur during sleep or during transitions between wake and sleep states. They disrupt sleep and can have a detrimental impact on the individual experiencing them. Our goal was to identify types of parasomnias and their prevalence in the current and recent post-secondary student population and to explore their coping strategies for parasomnias they found distressing.

The Rational Engineered Bacteria Based Biohybrid Living System for Tumor Therapy.

Living therapy based on bacterial cells has gained increasing attention for their applications in tumor treatments. Bacterial cells can naturally target to tumor sites and active the innate immunological responses. The intrinsic advantages of bacteria attribute to the development of biohybrid living carriers for targeting delivery toward hypoxic environments.

Shoutai pills for threatened abortion: A protocol for systematic review and meta-analysis.

Background: Threatened abortions are a serious health risk for women. Deferiprone tablets are commonly used in the treatment of clinical delivery. Traditional Chinese medicine, a characteristic medical system inherited for thousands of years, often applies Shoutai pills in the treatment of Threatened abortion and has achieved good results.

Integrated network pharmacology and molecular docking analyses of the mechanisms underlying the antihypertensive effects of lotusine.

Hypertension is a modifiable cardiovascular risk factor and cause of death worldwide. Lotusine, an alkaloid extracted from a plant used in traditional Chinese Medicine, has shown anti-hypertensive effects. However, its therapeutic efficacy requires further investigation.

Defining the Potential Targets for Biological Activity of Isoegomaketone Based on Network Pharmacology and Molecular Docking Methods.

Isoegomaketone is a water-soluble natural ketone compound that is commonly present in and . At present, it is known that isoegomaketone has a wide range of pharmacological activity, but there has been no thorough investigation of its potential targets. As a result, we examined the potential targets of isoegomaketone using the network pharmacology approach.

Advances in the Pharmacological Activities and Effects of Perilla Ketone and Isoegomaketone.

As components of a traditional Chinese herbal medicine with many physiological activities, perilla ketone and isoegomaketone isolated from perilla essential oil are important active components of . Recent studies have shown that these two compounds have promising antitumor, antifungal, antirheumatoid arthritis, antiobesity, anti-inflammatory, healing-promoting, and other activities and can be used to combat toxicity from immunotherapy. Therefore, the multitude of pharmacological activities and effects demonstrate the broad research potential of perilla ketone and isoegomaketone.

Root-secreted bitter triterpene modulates the rhizosphere microbiota to improve plant fitness.

Underground microbial ecosystems have profound impacts on plant health. Recently, essential roles have been shown for plant specialized metabolites in shaping the rhizosphere microbiome. However, the potential mechanisms underlying the root-to-soil delivery of these metabolites remain to be elucidated.

Genotype-Specific Recruitment of Rhizosphere Bacteria From Sandy Loam Soil for Growth Promotion of var. .

The composition and structure of the rhizosphere microbiome is affected by many factors, including soil type, genotype, and cultivation time of the plant. However, the interaction mechanisms among these factors are largely unclear. We use culture-independent 16S rRNA amplicon sequencing to investigate the rhizosphere bacterial composition and the structure of cultivated cucumber Xintaimici (XT) and wild-type cucumber var.

Cell Differentiation, Biofilm Formation and Environmental Prevalence.

is a soil-dwelling, spore-forming Gram-positive bacterium capable of cell differentiation. For decades, has been used as a model organism to study development of specialized cell types. In this minireview, we discuss cell differentiation in , covering both past research and recent progresses, and the role of cell differentiation in biofilm formation and prevalence of this bacterium in the environment.

Lightweight MWCNT/hollow mesoporous carbon/WPU composite material with excellent electromagnetic shielding performance.

With the rapid increase of intelligent communication equipment, electromagnetic pollution is becoming more and more serious, and the research and application of high-performance electromagnetic shielding materials have attracted great attention from the academic and engineering circles. Traditional metal-based electromagnetic shielding materials have high reflection loss, high density, and are difficult to process. Polymer-based materials with carbon materials as fillers have the advantages of flexibility, light weight, corrosion resistance and low processing costs.

Rationally designed structure of mesoporous carbon hollow microspheres to acquire excellent microwave absorption performance.

In this study, we used a novel and facile hard-template etching method to manufacture mesoporous carbon hollow microspheres (MCHMs). We prove that the dielectric ability and microwave absorption of MCHMs can be adjusted by structural characteristics. When the average particle size of MCHMs is 452 nm, the paraffin composite material mixed with 10 wt% MCHMs can achieve a maximum reflection loss value of -51 dB with a thickness of 4.

The effect of promoting hydrogen bond aggregation based on PEMTC on the mechanical properties and shape memory function of polyurethane elastomers.

In this work, small molecule diols named PEMTC were synthesized from isophorone diisocyanate, N-(2-hydroxyethyl)acrylamide and trimethylolpropane by a semi-directional method. PEMTC (2-(prop-2-enamido)ethyl N-{3-[({[2-ethyl-3-hydroxy-2(hydroxymethyl)propoxy]carbonyl}amino)methyl]-3,5,5-trimethylcyclohexyl}carbamate) contains hydrogen bond active site and light-initiated C=C. We introduced it as a branch chain block into poly(ε-caprolactone) (PCL).

Genomic insights into biocontrol potential of LJBS06.

Unlabelled: spp. have been widely reported with the ability to control plant diseases. In this work, we analyzed the whole genome of LJBS06, which was isolated from grapevine rhizosphere soil.

Negative Interplay between Biofilm Formation and Competence in the Environmental Strains of .

Environmental strains of the soil bacterium have valuable applications in agriculture, industry, and biotechnology; however, environmental strains are genetically less accessible. This reduced accessibility is in sharp contrast to laboratory strains, which are well known for their natural competence, and a limitation in their applications. In this study, we observed that robust biofilm formation by environmental strains of greatly reduced the frequency of competent cells in the biofilm.

The complete genome sequence of LPL061, an exopolysaccharide-producing bacterium.

LPL061, which shows strong exopolysaccharide (EPS) producing capacity, was isolated from carnations in Beijing, China. The complete genome of LPL061 comprised a single circular chromosome (3,907,268 bp; G+C content of 46.7%) with 3,737 coding DNA sequences, 26 rRNA, and 89 tRNA.

Complete genome sequence of LPL-K103, an antifungal cyclic lipopeptide bacillomycin L producer from the surface of lemon.

LPL-K103, which shows strong antifungal function, was isolated from the surface of lemon in Beijing, China. The complete genome of LPL-K103 contains a circular chromosome of 3,933,292 bp (46.61% G+C content).

The complete genome sequence of subsp. 01 and its integral components of antioxidant defense system.

The strain 01, isolated from centenarians, showed promising antioxidant potential in our previous studies. In this study, the genome information on strain 01 and the important antioxidant components are presented. The complete genome comprises a single circular chromosome (1,931,632 bp; 60.

Heterogeneity in respiratory electron transfer and adaptive iron utilization in a bacterial biofilm.

In Bacillus subtilis, robust biofilm formation requires large quantities of ferric iron. Here we show that this process requires preferential production of a siderophore precursor, 2,3-dihydroxybenzoate, instead of the siderophore bacillibactin. A large proportion of iron is associated extracellularly with the biofilm matrix.

Characterization of Subtilin L-Q11, a Novel Class I Bacteriocin Synthesized by L-Q11 Isolated From Orchard Soil.

Bacteriocins are peptides or proteins synthesized by bacterial ribosomes that show killing or inhibitory activities against different groups of bacteria. Bacteriocins are considered potential alternatives to traditional antibiotics, preservatives in pharmaceutical and food industries. A strain L-Q11 isolated from orchard soil was phylogenetically characterized as based on 16S rRNA gene sequencing analysis.

Purification and Characterization of Plantaricin LPL-1, a Novel Class IIa Bacteriocin Produced by LPL-1 Isolated From Fermented Fish.

Bacteriocins are ribosomally synthesized peptides or proteins possessing antibacterial activity against foodborne pathogens and spoilage bacteria. A novel bacteriocin, plantaricin LPL-1 was determined as a class IIa bacteriocin according to the YGNGV motif, and producer strain LPL-1 was identified based on physio-biochemical characteristics and 16S rDNA sequence. The novel bacteriocin, plantaricin LPL-1 was purified by salt precipitation, cation exchange, gel filtration, and reverse phase high-performance liquid chromatography (RP-HPLC).

The ClpY-ClpQ protease regulates multicellular development in Bacillus subtilis.

ATP-dependent proteases play essential roles in both protein quality control and the regulation of protein activities in bacteria. ClpYQ (also known as HslVU) is one of several highly conserved ATP-dependent proteases in bacteria. The regulation and biological function of ClpYQ have been well studied in Gram-negative bacteria, but are poorly understood in Gram-positive species.

L-S60 Reforms the Rhizosphere Bacterial Community and Improves Growth Conditions in Cucumber Plug Seedling.

Vegetable plug seedling has become the most important way to produce vegetable seedlings in China. This seedling method can significantly improve the quality and yield of vegetables compared to conventional methods. In the process of plug seedling, chemical fertilizers or pesticides are often used to improve the yield of the seedlings albeit with increasing concerns.

The complete genome sequence of Lactobacillus plantarum LPL-1, a novel antibacterial probiotic producing class IIa bacteriocin.

Bacteriocins are antibacterial proteins or peptides synthesized by ribosomes to inhibit or kill both closely related and non-related bacterium. Class IIa bacteriocins possess high activity against foodborne pathogen Listeria monocytogenes. A novel strain Lactobacillus plantarum LPL-1 was isolated from fermented fish and considered as a bacteriocin producing probiotic with great antibacterial activity against Listeria monocytogenes 54002.