Publications by authors named "Yuxingzi Chen"
Background: Phyllodes tumors (PTs) are breast neoplasms with varying degrees of malignancy, posing challenges in diagnosis and management. This case report focuses on a rare case of malignant phyllodes tumor of the breast (MPTB) in a 35-year-old woman.
Case Description: This case report presents a complex scenario of a patient with extensive breast abnormalities, including a malignant PT in the left breast, ductal carcinoma in both breasts, with axillary lymph node involvement.
Article Synopsis
- Papillary thyroid carcinoma (PTC) is the most common type of malignant thyroid tumor, and its ability to invade and metastasize affects patient outcomes; this study investigates the role of CCT2 in regulating these processes through EMT-related mechanisms.* -
- The research utilized techniques like qRT-PCR and Western blot to analyze CCT2 levels in PTC tissues, along with experiments using siRNA and overexpression vectors to explore the effects of CCT2 on cell behavior such as migration, invasion, proliferation, and apoptosis.* -
- Findings revealed that high levels of CCT2 in PTC tissues promote tumor cell migration, invasion, and growth while inhibiting apoptosis, by upregulating EMT genes, which underscores
Background: Medullary breast carcinoma (MBC) is a rare type of breast cancer. Our study aimed to compare the differences in clinical characteristics and prognosis between MBC and invasive ductal carcinoma (IDC), and to further develop and validate nomograms to predict overall survival (OS) and cancer-specific survival (CSS) in MBC patients.
Methods: A total of 179,613 patients from the Surveillance, Epidemiology and End Results (SEER) database from 2010 to 2015, including 596 MBC patients, were analyzed using the Kaplan-Meier method and propensity score matching (PSM) to compare patients' OS and CSS.
Background: The prognosis of patients with hormone receptor (HR)-positive breast cancer with liver metastasis (BCLM) remains dismal and varies widely from person to person. Thus, we sought to construct nomograms to predict overall survival (OS) and breast cancer-specific survival (BCSS) in patients with HR-positive BCLM using data from the Surveillance, Epidemiology and End Results (SEER) database.
Methods: The data of patients with BCLM, who had received HR-positive diagnoses between 2010 and 2016, were collected from the SEER database.
Background: With the development of precise treatment for breast cancer, the current trend of clinical treatment aims to limit axillary surgery as much as possible. At present, there is an unmet need to predict the probability of patients with a low risk of non-sentinel lymph node (SLN) metastasis and determine whether the omission of axillary lymph node dissection (ALND) is appropriate.
Methods: We retrospectively analyzed the data of patients with breast cancer who underwent sentinel lymph node biopsy (SLNB) and ALND.