Publications by authors named "Yuxing Dong"
Article Synopsis
- The rose fragrance molecule 2-phenylethanol (2-PE) is in high demand across cosmetics, food, and pharmaceutical industries, but current synthesis methods lack efficiency.
- This study used CRISPR-Cas9 metabolic engineering on the yeast Yarrowia lipolytica to significantly enhance the production of 2-PE, achieving a titer of 2.4 g/L with a yield of 0.06 g/g after optimizing various genetic pathways.
- The results demonstrate a successful approach for improving the biosynthesis of compounds derived from the shikimate pathway, setting a new standard for yeast-based production methods.
Objective: To evaluate the current status and equity of older adult resource allocation in the 31 provinces (autonomous regions and municipalities) of mainland China, and to offer recommendations for the optimization of these allocations.
Methods: Four key indicators, namely, the number of older adult institutions, employees, professionals, and beds in mainland China in the year 2020, were used and analyzed using various methods and tools, including agglomeration analysis, the Gini coefficient, and the Lorenz Curve. These methods were applied to evaluate the equity of older adult resource allocation across the different provinces (autonomous regions and municipalities) and regions of China, using two dimensions, namely, the geographical area and the older adult population.
[The method of inducing and establishing human pancreatic cancer cell sublines with radiation resistance].
Zhonghua Wai Ke Za Zhi
December 2006
Objective: To explore the method of inducing and building pancreatic cancer cell sublines with radiation resistance.
Methods: Simulating the clinical radiotherapy, the pancreatic cell lines SW1990, Capan-1 (Cap), AsPC-1 (ASPC), P3, PANC-1 (Pan-1) and MIAPaCa-2 (MIA) were repeatedly given individual dose of X-rays with liner accelerator to induce radiation resistance, the changes of cell morphology, cell cycle and radio sensibility in the induced cell lines were compared with the parental cell lines at the end of inducing course.
Results: Compared with the parental cells, there were significant changes in morphology in the pancreatic cancer cell sublines after the radiation.