Methods for improving the thermal performance of thermal bridges of lightweight steel-framed buildings.

The existence of a large number of thermal bridges in the Lightweight Steel-Framed (LSF) building leads to its energy loss. The reduction of the heat transfer of thermal bridges is crucial for increasing the thermal performance of the building envelope. In this study, the infrared technology was first used to measure the temperature of LSF buildings, and clear thermal bridge junctions were determined.

Photodissociation dynamics of H2S+ via the A2A1 (0, 8, 0) state.

The photodissociation dynamics of the hydrogen sulfide cation (H2S+) (X2B1) were investigated using the time-sliced velocity map ion imaging technique. S+ (4Su) product images were measured at four photolysis wavelengths around 393.70 nm, corresponding to the excitation of the H2S+ (X2B1) cation to the A2A1 (0, 8, 0) state.

Clinical and immunological characteristics of high-risk double-hit multiple myeloma.

At present, the characteristics of double-hit multiple myeloma (DHMM) are unknown. We retrospectively analyzed the clinical data from 433 new diagnosed MM patients and found that DHMM have a higher β2-MG level and percentage of bone marrow plasma cell. Cox regression analysis showed that the prognosis of DHMM was not limited by clinical indicators.

Research Progress on Viruses of .

, also known as passion fruit, is celebrated for its rich nutritional content, distinctive flavour, and significant medicinal benefits. At present, viral diseases pose a major challenge to the passion fruit industry, affecting both the production and quality of the fruit. These diseases impede the sustainable and healthy growth of the passion fruit sector.

Deep learning assisted quantitative detection of cardiac troponin I in hierarchical dendritic copper-nickel nanostructure lateral flow immunoassay.

The rising demand for point-of-care testing (POCT) in disease diagnosis has made LFIA sensors based on dendritic metal thin film (HD-nanometal) and background fluorescence technology essential for rapid and accurate disease marker detection, thanks to their integrated design, high sensitivity, and cost-effectiveness. However, their unique 3D nanostructures cause significant fluorescence variation, challenging traditional image processing methods in segmenting weak fluorescence regions. This paper develops a deep learning method to efficiently segment target regions in HD-nanometal LFIA sensor images, improving quantitative detection accuracy.

Family Functioning and Adolescent Mental Health: The Mediating Role of Bullying Victimization and Resilience.

This study aimed to understand the current state of adolescent mental health, explore the mediating effect of bullying victimization and resilience in the relationship between adolescent family functioning and mental health, and investigate gender differences in this association. A total of 4319 students (2347 boys and 1972 girls) completed the questionnaire. Mediating effects were analyzed using the framework of structural equation modeling and bootstrapping.

Passion fruit HD-ZIP genes: Characterization, expression variance, and overexpression PeHB31 enhanced drought tolerance via lignin pathway.

The HD-ZIP (homeodomain-leucine zipper) genes hold significant importance in transcriptional regulation, especially in plant development and responses to abiotic stresses. However, a comprehensive study targeting HD-ZIP family members in passion fruit has been absent. In our current research, 34 HD-ZIP family members (PeHBs) were identified by bioinformatics analysis.

A novel integrated lateral flow immunoassay platform for the detection of cardiac troponin I using hierarchical dendritic copper-nickel nanostructures.

Cardiac troponin I (cTnI) is a critical biomarker for the diagnosis of acute myocardial infarction (AMI). Herein, we report a novel integrated lateral flow immunoassay (LFIA) platform for highly sensitive point-of-care testing (POCT) of cTnI using hierarchical dendritic copper-nickel (HD-nanoCu-Ni) nanostructures. The electrodeposited HD-nanoCu-Ni film (∼22 μm thick) on an ITO-coated glass substrate exhibits superior capillary action and structural integrity.

FLT3-selective PROTAC: Enhanced safety and increased synergy with Venetoclax in FLT3-ITD mutated acute myeloid leukemia.

Acute myeloid leukemia (AML) patients carrying Fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) mutations often face a poor prognosis. While some FLT3 inhibitors have been used clinically, challenges such as short efficacy and poor specificity persist. Proteolytic targeting chimera (PROTAC), with its lower ligand affinity requirement for target proteins, offers higher and rapid targeting capability.

Development of a risk assessment model for cardiac injury in patients newly diagnosed with acute myeloid leukemia based on a multicenter, real-world analysis in China.

Background: Studies have revealed that acute myeloid leukemia (AML) patients are prone to combined cardiac injury. We aimed to identify hematological risk factors associated with cardiac injury in newly diagnosed AML patients before chemotherapy and develop a personalized predictive model.

Methods: The population baseline, blood test, electrocardiogram, echocardiograph, and genetic and cytogenetic data were collected from newly diagnosed AML patients.

The effect of short-form video addiction on undergraduates' academic procrastination: a moderated mediation model.

Background: Short-form videos have become one of the most popular ways for people to entertain and relax. However, the intense interest in short-form videos has given rise to short-video addiction, which poses risks to both physical and mental health of individuals. Undergraduates are one of the important users for short-form videos, and the influence of short-form video addiction calls for more attention.

Development of the Panic Response Scale and the Predicting Factors of Panic Response During the COVID-19 Pandemic.

Introduction: During emergencies, individuals and communities often react in a variety of ways, including panic response. However, the study of panic response is limited due to narrow assessment tools that measure only one or two dimensions of human response (eg, physiology, cognition, emotion, and behavior). To address this limitation and to explore the risk and protective factors of panic response during the global spread of the Coronavirus Disease 2019 (COVID-19), the current study developed and evaluated the (PRS).

Subsidy or not? How much government subsidy can improve performance level of energy-saving service company?

Contract energy management model is a new energy-saving mode based on single market mechanism. Due to its externality, the energy efficiency market cannot realize the optimal allocation of resources. Government energy-saving subsidy can solve the market failure of energy-saving service market and improve the performance level of energy-saving service company.

Comprehensive analysis of clinical prognostic features and tumor microenvironment landscape of CD11bCD64 patients with acute myeloid leukemia.

Background: Immunophenotyping surface molecules detected in the clinic are mainly applied in diagnostic confirmation and subtyping. However, the immunomodulatory molecules CD11b and CD64, are highly associated with leukemogenesis. Hence, the prognostic value of them and their potential biological functions merit further investigation.

Intergenerational effects of childhood maltreatment: The relationships among parental childhood emotional neglect, emotional expressiveness and children's problem behaviors.

Background: Childhood maltreatment has a severe impact on both the health and parenting styles of abused individuals in adulthood, and it even has a negative impact on the offspring of abused individuals. Although studies have confirmed the intergenerational effects of childhood maltreatment, relatively few have emphasized emotional neglect and its mechanism of intergenerational effects. Additionally, few studies have examined the unique role of fathers and how mothers and fathers interact with one another.

Identification and validation of immunohistochemical marker panels to predict the prognosis of muscle invasive bladder cancer.

Background: Currently, the treatment regimen of bladder cancer depends on the stage and grade. Yet, patients with similar histopathological characteristics may have distinct prognosis. Luminal/basal subtyping had proved to be a satisfactory subtyping method.

The Double-Edged Impact of the COVID-19 Pandemic on Chinese Family Relationships.

To comprehensively understand the Chinese family relationships (i.e., marital relationship, parent-child relationship, sibling relationship, and grandparent-grandchild relationship) during the COVID-19 pandemic, this study investigated the changes of family relationships and the individual differences related to knowledge of the COVID-19, personality traits (i.

dSTORM-Based Single-Cell Protein Quantitative Analysis Can Effectively Evaluate the Degradation Ability of PROTACs.

As an emerging therapeutic strategy, proteolysis-targeting chimeras (PROTACs) have been proven to be superior to traditional drugs in many aspects. However, due to their unique mechanism of action, existing methods for evaluating the degradation still have many limitations, which seriously restricts the development of PROTACs. In this methodological study, using direct stochastic optical reconstruction microscopy (dSTORM)-based single-cell protein quantitative analysis, we systematically investigated the dynamic degradation characteristics of FLT3 protein during PROTACs treatment.

Reaction N(D) + CHCCH (Allene): An Experimental and Theoretical Investigation and Implications for the Photochemical Models of Titan.

We report on a combined experimental and theoretical investigation of the N(D) + CHCCH (allene) reaction of relevance in the atmospheric chemistry of Titan. Experimentally, the reaction was investigated (i) under single-collision conditions by the crossed molecular beams (CMB) scattering method with mass spectrometric detection and time-of-flight analysis at the collision energy ( ) of 33 kJ/mol to determine the primary products and the reaction micromechanism and (ii) in a continuous supersonic flow reactor to determine the rate constant as a function of temperature from 50 to 296 K. Theoretically, electronic structure calculations of the doublet CHN potential energy surface (PES) were performed to assist the interpretation of the experimental results and characterize the overall reaction mechanism.

The N(D) + CHCHCN (Vinyl Cyanide) Reaction: A Combined Crossed Molecular Beam and Theoretical Study and Implications for the Atmosphere of Titan.

The reaction of electronically excited nitrogen atoms, N(D), with vinyl cyanide, CHCHCN, has been investigated under single-collision conditions by the crossed molecular beam (CMB) scattering method with mass spectrometric detection and time-of-flight (TOF) analysis at the collision energy, , of 31.4 kJ/mol. Synergistic electronic structure calculations of the doublet potential energy surface (PES) have been performed to assist in the interpretation of the experimental results and characterize the overall reaction micromechanism.

Observation of Competitive Nonadiabatic Photodissociation Dynamics of HS Cations.

A comprehensive understanding of dissociation mechanisms is of fundamental importance in the photochemistry of small molecules. Here, we investigated the detailed photodissociation dynamics of HS near 337 nm by using the velocity map ion imaging technique together with the theoretical characterizations by developing global full-dimensional potential energy surfaces (PESs). Rotational state resolved images were acquired for the S(S) + H product channel.

Preparation of YO/TiO-Loaded Polyester Fabric and Its Photocatalytic Properties under Visible Light Irradiation.

In this study, YO/TiO-loaded polyester fabric was prepared to improve the catalytic activity of the TiO and to increase its reuse efficiency. The samples were systematically characterized by scanning electron microscopy (SEM), X-ray diffractometry (XRD), X-ray photoelectron spectroscopy (XPS), and infrared spectroscopy (FT-IR). Furthermore, the degradation performance of methyl orange in the presence of simulated visible light irradiation was also investigated.

Crossed Molecular Beam Study of the H + HD → H + D Reaction at 0.60 and 1.26 eV Using the Near-Threshold Ionization Velocity Map Ion Imaging.

By using the 1 + 1' near-threshold ionization velocity map ion imaging technique, state-to-state reactive differential cross sections have been measured for the H + HD → H + D reaction. High-resolution images of the D products, with the rotational states of the H co-products clearly resolved, were acquired at the collision energies of 0.60 and 1.

Cardiac-Related Lesions in Newly Diagnosed Patients With Acute Leukemia: A Chinese Population-Based Real-World Study.

The relationship between newly diagnosed acute leukemia (AL) and heart-related lesions remains unclear. This study aimed to investigate baseline cardiac function and risk of cardiovascular diseases (CVDs) in patients with new-onset AL, and provide data on cardiac management strategies for patients with AL. We retrospectively collected data on baseline characteristics, echocardiography, and biochemical blood indicators (e.

The empathy questionnaire for children and adolescents (EmQue-CA) in Chinese: Psychometric properties and measurement invariance.

The current study aimed to evaluate the reliability and validity of the Chinese version of the EmQue-CA, as well as the measurement invariance across gender. A sample of 1107 students (498 boys and 609 girls) enrolled in fourth grade to twelfth grade (M = 13.29; SD = 2.