Publications by authors named "Yuxiao Zhu"
Peroxymonosulfate (PMS)-based advanced oxidation processes have shown potential for the removal of organic contaminants; however, the preparation of catalysts with high degradation efficiencies and rapid reaction rates remains a challenge. In this study, we have successfully synthesized CoFe bimetallic modified corn cob-derived biochar (CoFe/BC) for the activation of PMS, achieving the rapid and efficient degradation of bisphenol F (BPF). The synthesized CoFe/BC catalyst demonstrated excellent catalytic performance, achieving over 99% removal within 3 min and exhibiting a removal rate of 90.
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- * The Co and Cu co-doped sawdust biochar (CoO/CuO@CBC) catalyst shows superior performance, with a degradation rate constant that is 30 times higher compared to other systems, demonstrating its effectiveness under various conditions.
- * The degradation process involves both radical and non-radical pathways, highlighting the potential of the CoO/CuO@CBC catalyst for practical applications in environmental remediation.
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- Mosquitoes are impacted by temperature changes, and the study looks at how Culex pipiens pallens (Cx. pallens) responds to sudden heat increases, examining both larvae and adult mosquitoes.
- The results showed that extreme temperatures (especially 42 °C) lead to high mortality rates, with adult males being the most vulnerable compared to larvae and females.
- Overall, prolonged heat exposure notably reduced larvae development and male reproductive success, indicating that temperature shifts can affect mosquito populations and inform pest management strategies.
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- * Short-term exposure to PET-MPs caused a mild stress response but did not significantly affect nitrogen removal, whereas long-term exposure led to a 28.7% decrease in nitrogen removal efficiency.
- * Despite initial negative effects, anammox activity gradually recovered over three months, suggesting that changes in microbial communities and metabolic interactions influenced the sludge's response to PET-MP exposure.
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- * A discovered peptide, SjDX5-271, promotes M2 macrophage polarization and protects mice from liver IRI, but its effectiveness is lost when macrophages are removed.
- * SjDX5-271 works by inhibiting the TLR4/MyD88/NF-κB signaling pathway, reducing inflammation in IRI, and suggests potential new treatments for IRI and related immune diseases.
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- * The ZMC-2 catalyst showed impressive photocatalytic activity under visible light, achieving a 99.6% removal efficiency of methylene blue dye across various pH levels due to enhanced electron movement from Zn and the conductive carbon sphere.
- * The degradation mechanism involved reactive radicals, and the catalyst demonstrated sustained performance over five cycles, suggesting great potential for developing effective carbon-based photocatalytic materials.
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- * Researchers created covalent complexes of β-lactoglobulin (LG) and dicaffeoylquinic acids (DCQAs) using ultrasound and free radicals to enhance curcumin delivery.
- * Findings revealed structural changes in LG due to the interactions, and the complexes effectively embedded up to 62% of curcumin, showcasing ultrasound's role in improving protein-polyphenol systems.
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- Dysbiosis in gut microbiota affects glucose metabolism, and this study investigates the impact of washed microbiota transplantation (WMT) on glycemic variability in diabetes patients.
- Fourteen patients underwent three WMTs, with their progress monitored for insulin use, glucose levels, and gut microbiome changes over time.
- Results showed significant improvements in insulin dosage, glucose excursions, and gut microbial diversity, suggesting that targeting gut microbiota through WMT could effectively reduce glycemic variability in diabetes management.
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- Regulatory T cells (Tregs) are important in managing autoimmune and inflammatory diseases, and parasitic helminths can help induce Tregs, presenting a potential therapeutic strategy.
- In this study, a specific peptide (SjDX5-53) was identified from Schistosoma japonicum egg extracts, which enhances Treg production and function while suppressing dendritic cell activation.
- SjDX5-53 demonstrated promising results in mouse models by protecting against autoimmune colitis and psoriasis, underscoring its potential as a new treatment derived from helminth biology.
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- * The study involved multiple groups, where we found that the prevalence of UBE2L3-Ab was significantly higher in T1DM patients from both Chinese (9.33%) and American (3.86%) backgrounds compared to their respective control groups, with notable differences between the two ethnicities.
- * While UBE2L3-Ab is more common in T1DM patients, it might not be
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- Salinization poses a significant threat to maize growth, particularly during the seedling phase, and circular RNAs (circRNAs) are crucial for plant stress resistance.
- A genome-wide association study identified 5 key SNPs and 86 candidate genes related to maize survival under salt stress, along with RNA sequencing revealing 371 circRNAs responsive to salt treatment.
- The research established a circRNA/miRNA/mRNA regulatory model for enhancing salt stress tolerance in maize and identified a beneficial gene variant linked to salt tolerance, aiding in the development of more resilient maize varieties.
Enestroburin is the first strobilurin fungicide developed by China and has been widely used to control fungal disease for 15 years. Investigation of its photolytic behaviour is essential for the comprehensive evaluation of its ecological risk. The effects of solution pH, humic acid (HA) and Fe(III) ions on photolysis were studied.
View Article and Find Full Text PDFPredictive Modeling of MAFLD Based on Hsp90α and the Therapeutic Application of Teprenone in a Diet-Induced Mouse Model.
Front Endocrinol (Lausanne)
February 2022
Background And Aims: The heat shock protein (Hsp) 90α is induced by stress and regulates inflammation through multiple pathways. Elevated serum Hsp90α had been found in nonalcoholic steatohepatitis (NASH). Geranylgeranylacetone (GGA, also called teprenone) is a terpenoid derivative.
View Article and Find Full Text PDFPyrisoxazole, an isoxazoline-class fungicide, has been registered and used for approximately 19 years. However, its environmental transformation products (TPs) and corresponding ecotoxicological effects remain ambiguous. In this study, the photolysis, hydrolysis, and soil transformation behavior of pyrisoxazole were systematically investigated by indoor simulation experiments and analyzed by liquid chromatography quadrupole-time-of-flight mass spectrometry (LC-QTOF-MS) and UNIFI software.
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- * The study examined 300 maize inbred lines for seed germination traits under low temperatures (10 °C) and identified 15 significant SNPs associated with cold stress using the FarmCPU model in GWAS.
- * Ten genes were linked to three SNP loci related to chilling tolerance, and these genes are known to contribute to plant resilience against various abiotic stresses, enhancing our understanding of maize germination under cold conditions.
The host-parasite relationship is based on subtle interplay between parasite survival strategies and host defense mechanisms. It is well known that helminth infection, which afflicts more than one billion people globally, correlates with a decreased prevalence of obesity. Dissecting the underlying mechanisms can provide new targets for treating obesity from the host-parasite interaction perspective.
View Article and Find Full Text PDFEvaluation of clean-up procedures and sample dilution in multi-residue pesticide analysis of spices and herbs by UPLC-MS/MS.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
February 2021
The matrix effect in complex spices and herbs presents a great challenge to the simultaneous, rapid, quantitative analysis of multiple pesticides by mass spectrometry. The aim of this work was to develop and validate an effective UPLC-MS/MS multi-residue method for the analysis of pesticide residues to reduce matrix effects in four spices and one herb and infer which component caused the matrix effect in black pepper. In this paper, we highlight the importance of reducing matrix effects.
View Article and Find Full Text PDFDifferential Profile of Plasma Circular RNAs in Type 1 Diabetes Mellitus.
Diabetes Metab J
December 2020
Article Synopsis
- Researchers investigated plasma circular RNAs (circRNAs) as potential biomarkers for type 1 diabetes mellitus (T1DM) because current treatments are inadequate.
- They found 68 differentially expressed circRNAs in T1DM patients, identifying potential roles in inflammation related to the disease.
- The study suggests that circRNAs could serve as novel biomarkers for T1DM, warranting further research into their implications in disease mechanisms.
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- The study compares a new electrochemiluminescence (ECL) assay for detecting GAD65 autoantibodies with an established radiobinding assay in diagnosing latent autoimmune diabetes in adults (LADA).
- Serum samples from 141 LADA patients, along with samples from type 1 and type 2 diabetes patients, were tested to evaluate the accuracy and effectiveness of the new ECL-GAD65 antibody assay.
- Results showed that ECL-positive LADA patients exhibited traits similar to type 1 diabetes, such as being leaner and having poorer β-cell function, indicating that ECL can help better define LADA subtypes.
Background: The aim of this study was to present a modified pancreatojejunostomy technique for laparoscopic pancreaticoduodenectomy (LPD) and to evaluate its safety and reliability.
Methods: Clinical data from 67 patients who underwent LPD at a single center, from September 2016 to December 2017 were retrospectively collected and analysed. Of these patients, 31 cases were subjected to modified pancreatojejunostomy (modified group), and 36 cases received duct-to-mucosa pancreatojejunostomy (control group) for LPD.
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- Novel therapeutics are needed due to rising antibiotic resistance, and antimicrobial peptides like HPRP-A1/A2 show potential against multidrug-resistant pathogens.
- HPRP-A1/A2 significantly reduced the viability and invasiveness of Toxoplasma gondii tachyzoites by damaging their membranes.
- In vivo studies demonstrated that these peptides activate a strong immune response in infected mice, making HPRP-A1/A2 a promising alternative treatment for T. gondii infection.
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- PPAR- is crucial in managing metabolic disorders and immune responses, particularly regarding regulatory T cells (Tregs), which help maintain immune tolerance and regulate responses to infections.
- The study involved testing the effects of pioglitazone (a PPAR- agonist) on tissue samples from infected mice, measuring changes in Treg cell percentages, and assessing gene expression linked to PPAR- and Foxp3.
- Results showed that pioglitazone reduced liver and spleen pathology, increased Treg cell populations, and enhanced Foxp3 expression, indicating a significant role for PPAR-/Foxp3 signaling in managing immune response and inflammation.
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- * Overall analysis found no significant association between rs4919510 and cancer risk across all genetic models but noted a reduced risk for colorectal cancer and a potential increased risk for papillary thyroid cancer based on specific genetic models.
- * The rs4919510 GG genotype was linked to poorer recurrence-free survival among cancer patients, indicating the need for further research on larger populations to confirm these findings.
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- The study examines how social contagion behaves on weighted networks, which are networks where connections between nodes have different strengths.
- It reveals that the uneven distribution of connections (degree heterogeneity) can change the way contagion spreads, and its effect on the total number of people adopting something varies based on transmission probabilities.
- Additionally, the research concludes that while the variation in connection weights always makes it harder for social contagion to spread, it does not change the type of transition in contagion dynamics.
Background: Epidemiological studies in China have revealed that Schistosoma japonicum infection is inversely correlated with metabolic syndrome, even after repeated chemotherapy with praziquantel (PZQ). We investigated the effect of chronic S. japonicum infection, PZQ chemotherapy, and soluble egg antigen (SEA) treatment on whole-body metabolic homeostasis and hepatic insulin sensitivity in mouse models.
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