Publications by authors named "Yuxiao Xue"
Intracerebral hemorrhage (ICH) is a severe subtype of stroke linked to high morbidity and mortality rates. However, the underlying mechanisms of neuronal injury post-ICH remain poorly understood. In this study, we investigated sphingolipid metabolism alterations in neurons using lipidomics and explored the regulatory mechanisms involved.
View Article and Find Full Text PDFArticle Synopsis
- Recent studies show that oxidative stress from intracerebral hemorrhage (ICH) damages neurons and disrupts cell functions, but the mechanisms for maintaining neuronal stability are not fully understood.
- Research using metabolomics, RNA sequencing, and CUT&Tag-seq explored how the PERK/ATF4 pathway related to endoplasmic reticulum stress interacts with mitochondrial one-carbon metabolism in neurons.
- The results indicate that the interaction between GRP78, PERK, ATF4, and mitochondrial one-carbon metabolism is crucial for neuron stability post-ICH, suggesting potential new treatments by modifying these pathways or providing additional NADPH.
An optical fiber sensor based on a hole-assisted dual-core fiber (HADCF) has been proposed and experimentally demonstrated for dual-parameter measurements. The dual-mode interferometer created uses the LP mode and LP mode in the suspended core of a specialist optical fiber, combined with a directional coupler formed by using the suspended core and the center core in a 16 mm long HADCF. Using this, the simultaneous measurement of salinity (due to the presence of NaCl) and temperature has been achieved through monitoring the interference dip and resonance dip.
View Article and Find Full Text PDFArticle Synopsis
- This research introduces a one-step method for producing activated carbon from low-rank coal using oxidized pellets, enabling simultaneous production of activated carbon and direct reduction iron without generating solid waste.
- The activated carbon produced achieves impressive properties, including a high specific surface area of 370.42 m²/g and excellent performance in desulfurization and denitrification when tested against commercial activated carbon.
- The process demonstrates strong technical and economic feasibility, indicating potential for effective environmental applications by improving air quality through enhanced gas purification.