Bibliometric analysis of T cells in allergic rhinitis.

Unlabelled: By reviewing the relevant literature in the field of T cell and allergic rhinitis, we determined the development status, study hotspots, and research frontiers viewpoints of this field to provide a reference for researchers and clinical workers.

Methods: Web of Science Core Collection (WoSCC) was applied to obtain the studies related to T cells and allergic rhinitis (AR) from 2003 to 2023, and the information extracted from these studies was analyzed using CiteSpace 6.1.

Immunomodulation in allergic rhinitis: Insights from Th2 cells and NLRP3/IL-18 pathway.

Allergic rhinitis (AR) is characterized by nasal symptoms such as rubbing and sneezing, often triggered by allergen exposure. The purpose of this study is to dissect the roles of NLRP3-mediated immune modulation and macrophage pyroptosis in modulating T cell differentiation within the context of ovalbumin (OVA)-induced AR in mice. OVA-induced AR was established in mice, evaluating nasal symptoms, macrophage infiltration, cytokine levels, and T cell differentiation.

HiOmics: A cloud-based one-stop platform for the comprehensive analysis of large-scale omics data.

Analyzing the vast amount of omics data generated comprehensively by high-throughput sequencing technology is of utmost importance for scientists. In this context, we propose HiOmics, a cloud-based platform equipped with nearly 300 plugins designed for the comprehensive analysis and visualization of omics data. HiOmics utilizes the Element Plus framework to craft a user-friendly interface and harnesses Docker container technology to ensure the reliability and reproducibility of data analysis results.

Atmospheric organic nitrogen deposition around the Danjiangkou Reservoir: Fluxes, characteristics and evidence of agricultural source.

Dissolved organic nitrogen (DON) deposition was the substantial component of dissolved total nitrogen (DTN) deposition in the world's nitrogen deposition hot spots areas. However, the information on the importance for DON deposition and its sources was still scarce, which limited the comprehensive assessment of the ecological threat from nitrogen deposition. Six sampling sites around the Danjiangkou Reservoir were set up to collect the dry and wet deposition samples from October 2017 to September 2021.

[Characteristics of Eukaryotic Phytoplankton Community Structure and Its Relationship with Environmental Factors in Danjiangkou Reservoir].

Eukaryotic phytoplankton play crucial roles in ecosystem processes, and understanding their community composition and abundance is of great importance to protect the balance of aquatic ecosystems. Danjiangkou Reservoir is a canyon lake in central China that acts as the water source of the Mid-route of South-to-North Water Diversion Project. In this study, the composition of planktonic microeukaryotes from water samples with a depth ranging from 0.

Clinical Value Screening, Prognostic Significance, and Key Gene Identification of TrkB in Laryngeal Carcinoma.

Purpose: Using human gene chip expression profiling technology to screen out downstream genes related to TrkB regulation in laryngeal cancer cells.

Methods: Using the Hep-2 TrkB shRNA cell line, divide it into an experimental group (shNTRK2) and a control group (PLKO1), and use the human gene expression microarray to screen out the differential genes. Then, select 10 upregulated genes and 10 downregulated genes from the differential genes, and use RT-PCR to verify whether the screening results of human gene expression microarray profiles are reliable.

Relationship between Patients' Baseline Characteristics and Survival Benefits in Immunotherapy-Treated Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis.

Background: The difference of patients' baseline characteristics such as sex, age, Eastern Cooperative Oncology Group performance status (ECOG PS), and smoking status may influence the immune response. However, little is known about whether these factors affect the efficacy of immune checkpoint inhibitors (ICIs) in patients with advanced non-small-cell lung cancer (NSCLC). Therefore, we performed this systematic review and meta-analysis to investigate the relationship between patients' baseline characteristics and survival benefits in immunotherapy-treated NSCLC.

Association between the rs3733846 in the flanking region of miR-143/145 and risk of cervical squamous cell carcinoma.

To investigate the effect of rs3733846 in the flanking region of miR-143/145 on susceptibility to cervical squamous cell carcinoma (CSCC). We collected venous blood samples from 242 CSCC patients and 250 healthy controls. The rs3733846 polymorphism was genotyped by SnaPshot and Sanger sequencing.

Feasibility of modified radical mastectomy with nipple-areola preservation combined with stage I prosthesis implantation using air cavity-free suspension hook in patients with breast cancer.

Background: Mastoscopic surgery is proven to have lower incidence of postoperative complications and better postoperative recovery than traditional breast cancer surgery. This study aimed to examine the feasibility of mastoscopic modified radical mastectomy (MRM) with skin nipple-areola preservation under air cavity-free suspension hook and stage I silicone prosthesis implantation (SMALND) compared with routine MRM.

Methods: This was a retrospective study of patients who underwent MRM for breast cancer at the Shengjing Hospital Affiliated to China Medical University between January 1, 2019, and June 30, 2019.

Ensuring effective implementation of the post-2020 global biodiversity targets.

Biodiversity underpins the fundamental elements for human well-being including food security, human health and access to clean water. In 2010, the Aichi Targets were adopted by world leaders to address the crisis of biodiversity loss. Despite conservation efforts, none of the Aichi Targets have been fully met.

ERK Activation-Mediated Autophagy Induction Resists Licochalcone A-Induced Anticancer Activities in Lung Cancer Cells .

Introduction: The incidence and mortality rates of lung cancer rank top in the different types of cancers in China. Licochalcone A (LA) is a flavonoid extracted from the roots of licorice with antitumor effects in various cancers and . However, the role of LA in non-small cell lung cancer (NSCLC) remains largely unclear.

The complete mitochondrial genome of (Charadriiformes: Scolopacidae).

There is a lack of genomic information on , which can provide valuable resource for genetic diversity and conservation biology. The complete mitogenome of was 16,775 bp in length and contained 13 protein-coding genes (PCGs), 2 ribosomal RNA (rRNA) genes, 22 transfer RNA (tRNA) genes and 1 control region (D-loop). The overall nucleotide composition was 31.

[Characteristics of Macrobenthos Community Structure and Their Relationships with Environmental Factors in Rivers of Beijing in Spring].

Macrobenthos from 20 sites of 17 rivers in Beijing were investigated in the spring of 2019, and the relationship between community structure characteristics and environmental factors was analyzed. A total of 64 classification units (species) of macrobenthos from 3 phyla, 6 classes, and 32 families were identified. We found that there were large spatial differences between the density composition and dominant species of macrobenthos.

[Analysis of River Zooplankton Community Characteristics in Autumn in Beijing].

To clarify the spatial distribution characteristics of zooplankton communities and the relationship between zooplankton and water environmental factors, 81 samples from 28 rivers and lakes in Beijing were collected in September 2017. A total of 68 species of zooplankton were identified, including 17 species of protozoa (25%), 36 species of rotifers (53%), 13 species of cladocera (19%), and copepods (3%, which were mainly copepodids and nauplii). Among 15 dominant species, 12 were copepods and rotifers.

Phylogeography, speciation and demographic history: Contrasting evidence from mitochondrial and nuclear markers of the Odorrana graminea sensu lato (Anura, Ranidae) in China.

Understanding the process of speciation and the factors driving the geographical distribution patterns of species is of great interest in ecology and evolutionary biology. Herein, we investigated the phylogeographic patterns, speciation, demographic history and genetic structure of the widespread endemic Odorrana graminea sensu lato in Southern China and adjacent areas. A total of 439 specimens from 68 localities were sequenced and analyzed for both mitochondrial (12S and 16S rRNA) and nuclear markers (RAG-1 and ten microsatellite loci).

The complete mitochondrial genome of the Spotted Greenshank (Charadriiforemes: Charadriidae).

The complete mitochondrial DNA genome of the Endangered Spotted Greenshank, , was detected using phenol-chloroform extraction procedure and polymerase chain reaction method. It is a circular molecule of 16,935 bp in size, exhibits the typical structure of mitochondrial genomes of Charadriiformes, containing 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and a control region. Overall base composition of the complete mitochondrial DNA is A (31.

Effect of Sewage Irrigation on the CT-Measured Soil Pore Characteristics of a Clay Farmland in Northern China.

Sewage irrigation has a strong influence on the physical, chemical, and biological properties of soil. However, the effects of sewage irrigation on the pore characteristics of soil are not well understood. This study compares the effects of sewage irrigation and groundwater irrigation on computed tomography (CT)-measured pore parameters and examines the relationships between CT-measured pore parameters and soil physicochemical and microbial properties.

Integrated Oncogenomic Profiling of Copy Numbers and Gene Expression in Lung Adenocarcinomas without Mutations or Fusion.

Targeted therapies based on mutations or on the fusion oncogene have become the standard treatment for certain patients with lung adenocarcinoma (LUAD). However, most LUAD patients have no mutation or fusion, and their oncogenetic alterations remain to be characterized. Here we conducted an integrated analysis of public datasets to assess the genomic alterations of 23 highly lung cancer-associated genes.

Morphological and physiological responses of Heteropogon contortus to drought stress in a dry-hot valley.

Background: Heteropogon contortus is a valuable pasture species that is widely used for vegetation restoration in dry-hot valleys of China. However, to date, its morphological and physiological responses to drought, and the underlying mechanisms are not well understood. This study was aimed to investigate the morphological and physiological changes of H.

The complete mitochondrial genome sequence of Beaufortia szechuanensis (Cypriniformes, Balitoridae).

The Beaufortia szechuanensis is endemic to the upper reaches of Yangtze River in China. In this study, we successfully sequenced the mitochondrial genome of the B. szechuanensis, collected from the Qingyi River.

Agricultural non-point nitrogen pollution control function of different vegetation types in riparian wetlands: a case study in the Yellow River wetland in China.

Riparian wetland is the major transition zone of matter, energy and information transfer between aquatic and terrestrial ecosystems and has important functions of water purification and non-point pollution control. Using the field experiment method and an isotope tracing technique, the agricultural non-point nitrogen pollution control function of different vegetation types in riparian wetland was studied in the Kouma Section of the Yellow River. The results showed that the retention of agricultural non-point nitrogen pollution by riparian wetland soil occurs mainly in top 0-10 cm layer.