Sugemule-7 alleviates oxidative stress, neuroinflammation, and cell death, promoting synaptic plasticity recovery in mice with postpartum depression.

Postpartum depression (PPD) profoundly impacts the mental and physical health of women globally and is an incurable psychological disorder. Traditional pharmacological treatments often have strong side effects and may adversely affect infant health through breastfeeding, underscoring the critical need for natural and gentle treatment strategies. Sugemule-7, a traditional Chinese medicine comprising multiple natural plant ingredients, represents a potentially safer and more effective alternative.

Real time detection and identification of fish quality using low-power multimodal artificial olfaction system.

Single gas quantification and mixed gas identification have been the major challenges in the field of gas detection. To address the shortcomings of chemo-resistive gas sensors, sensor arrays have been the subject of recent research. In this work, the research focused on both optimization of gas-sensing materials and further analysis of pattern recognition algorithms.

3D Printed Calcium Phosphate Physiochemically Dual-Regulating Pro-Osteogenesis and Antiosteolysis for Enhancing Bone Tissue Regeneration.

Osteoblasts and osteoclasts are two of the most important types of cells in bone repair, and their bone-forming and bone-resorbing activities influence the process of bone repair. In this study, we proposed a physicochemical bidirectional regulation strategy via ration by physically utilizing hydroxyapatite nanopatterning to recruit and induce MSCs osteogenic differentiation and by chemically inhibiting osteolysis activity through the loaded zoledronate. The nanorod-like hydroxyapatite coating was fabricated via a modified hydrothermal process while the zoledronic acid was loaded through the chelation within the calcium ions.

3D printing of customized bioceramics for promoting bone tissue regeneration by regulating sympathetic nerve behavior.

Numerous studies have shown that there are multiple neural activities involved in the process of bone resorption and bone regeneration, and promoting osteogenesis by promoting neural network reconstruction is an effective strategy for repairing critical size bone defects. However, traumatic bone defects often cause activation of the sympathetic nervous system (SNS) in the damaged area, releasing excess catecholamines (CAs), resulting in a decrease in the rate of bone formation. Herein, a 3D-printed scaffold loaded with propranolol (PRN) is proposed to reduce CA concentrations in bone defect areas and promote bone regeneration through drug release.

Characters of the family in wheat and function in salt stress tolerance.

encodes the last key glucuronosyltransferase for ionic stress sensor glycosyl inositol phosphoryl-ceramide (GIPCs) biosynthesis in , which indicates that the gene family play important role in plant tolerance to salt stress. However, the isolation and function of in staple crops have not been reported and the downstream targets of in salt stress tolerance signalling pathway are not clear. In this study, we identified 110 genes in wheat which were classified into five clades and they differed in gene structure, protein length, conserved motifs and expression profiles in different tissues and under salt stress.

Characterization of SEC14 family in wheat and the function of TaSEC14-7B in salt stress tolerance.

Phospholipids are important components of plant biofilms and signal transduction. They are divided into glycerophospholipids and sphingolipids. Phosphatidylinositol (PI) is an intracellular glycerophospholipid.

A low-power and flexible bioinspired artificial sensory neuron capable of tactile perceptual and associative learning.

Biomimetic haptic neuron systems have received a lot of attention from the booming artificial intelligence industry for their wide applications in personal health monitoring, electronic skin, and human-machine interfaces. In this work, inspired by the human tactile afferent nerve, we developed a flexible and low energy consumption artificial tactile neuron, which was constructed by combining a dual network (DN) hydrogel-based sensor and a low power memristor. The tactile sensor (ITO/PAM:CS-Fe hydrogel/ITO) serves as E-skin, with mechanical properties including pressure and stretching.

Tuning reactivity of BiMoO nanosheets sensors toward NH via Ag doping and nanoparticle modification.

Noble metal-doping and modification are proved effective in improving the gas-response performance of semiconductor sensors. In this study, we developed a promising BiMoO (BMO)-based gas sensor capable of sensing ppb-level NH at room temperature via introducing silver (Ag). The BMO samples with different Ag doping and modification ratios were successfully formed via one-step solvothermal and glucose reduction techniques, respectively, which could be confirmed by the results of X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HR-TEM) techniques.

A bio-inspired tactile nociceptor constructed by integrating wearable sensing paper and a VO threshold switching memristor.

The sensations of touch and pain are fundamental components of our daily life, which can transport vital information about the surroundings and provide protection to our bodies. In this study, the transmission process of sensing pressure stimuli to dorsal root neurons (nociceptors) was simulated using electronic devices. In this regard, we proposed and experimentally demonstrated a biomimetic nociceptor system with tactile perception.

Flexible silicon nanowires sensor for acetone detection on plastic substrates.

Acetone commonly exists in daily life and is harmful to human health, therefore the convenient and sensitive monitoring of acetone is highly desired. In addition, flexible sensors have the advantages of light-weight, conformal attachable to irregular shapes, etc. In this study, we fabricated high performance flexible silicon nanowires (SiNWs) sensor for acetone detection by transferring the monocrystalline Si film and metal-assisted chemical etching method on polyethylene terephthalate (PET).

TaFLZ2D enhances salinity stress tolerance via superior ability for ionic stress tolerance and ROS detoxification.

Salinity stress severely affects plant growth and crop productivity. FCS-like zinc finger family genes (FLZ) play important roles in plant growth and stress responses. But most information of this family obtained was involved in sucrose signaling, limited function has been known in response to salinity stress.

First-principles prediction of strain-induced gas-sensing tuning in tin sulfide.

A challenge in the application of two-dimensional (2D) SnS in gas-sensing field is that the SnS monolayer is highly sensitive to oxidizing gases, whereas it is naturally deactivated towards reducing gases. The non-sensitivity of SnS to reducing gases is a problem that needs to be solved urgently in an economic and effective manner. Hence, in this work, we propose a strategy of applying strain modulation on the SnS monolayer to optimize its sensitivity and selectivity for reducing gases fundamentally.

Layered Double Oxides for Sensing Reducing Volatile Organic Compounds: The Effect of Local Charge Region Modulation.

Multi-metal oxides with uniform distribution of various metal elements have potential for an enhanced gas-sensing response due to the strong heterogeneous and synergistic effects involved. In this study, three layered double oxides, labeled as CuCr-, ZnCr-, and ZnTi-LDOs, respectively, were prepared with corresponding LDHs (layered double hydroxides) as precursors and self-sacrificial templates. The elemental mapping confirms the uniform distribution of hetero-metal elements in whole LDOs.

Genome-Wide Association Study Uncover the Genetic Architecture of Salt Tolerance-Related Traits in Common Wheat ( L.).

Soil salinity is a serious threat to wheat yield affecting sustainable agriculture. Although salt tolerance is important for plant establishment at seedling stage, its genetic architecture remains unclear. In the present study, we have evaluated eight salt tolerance-related traits at seedling stage and identified the loci for salt tolerance by genome-wide association study (GWAS).

Using Deep Neural Network to Diagnose Thyroid Nodules on Ultrasound in Patients With Hashimoto's Thyroiditis.

Objective: The aim of this study is to develop a model using Deep Neural Network (DNN) to diagnose thyroid nodules in patients with Hashimoto's Thyroiditis.

Methods: In this retrospective study, we included 2,932 patients with thyroid nodules who underwent thyroid ultrasonogram in our hospital from January 2017 to August 2019. 80% of them were included as training set and 20% as test set.

Identification and Characterization of Wheat Germplasm for Salt Tolerance.

Salinity is one of the limiting factors of wheat production worldwide. A total of 334 internationally derived wheat genotypes were employed to identify new germplasm resources for salt tolerance breeding. Salt stress caused 39, 49, 58, 55, 21 and 39% reductions in shoot dry weight (SDW), root dry weight (RDW), shoot fresh weight (SFW), root fresh weight (RFW), shoot height (SH) and root length (RL) of wheat, respectively, compared with the control condition at the seedling stage.

First-principles calculations combined with experiments to study the gas-sensing performance of Zn-substituted SnS.

Two-dimensional group-IV monochalcogenides MX (M = Ge, and Sn; X = S, and Se) are explored for their potential in gas-sensing applications. In this work, a combined theoretical and experimental study on pure SnS and Zn-substituted SnS for promising methanol sensors is performed. The adsorption characteristics of methanol on pure and Zn-substituted SnS were first calculated using first-principles based on density functional theory (DFT).

A genome-wide analysis of pentatricopeptide repeat (PPR) protein-encoding genes in four Gossypium species with an emphasis on their expression in floral buds, ovules, and fibers in upland cotton.

Cotton is the most important natural fiber used in textiles. Breeding for "three-lines", i.e.

Effect of the Functionalization of Porous Silicon/WO₃ Nanorods with Pd Nanoparticles and Their Enhanced NO₂-Sensing Performance at Room Temperature.

The decoration of noble metal nanoparticles (NPs) on the surface of metal oxide semiconductors to enhance material characteristics and gas-sensing performance has recently attracted increasing attention from researchers worldwide. Here, we have synthesized porous silicon (PS)/WO₃ nanorods (NRs) functionalized with Pd NPs to enhance NO₂ gas-sensing performance. PS was first prepared using electrochemical methods and worked as a substrate.

Hierarchical layered double hydroxides with Ag nanoparticle modification for ethanol sensing.

Layered double hydroxides (LDHs) have recently been revealed to be promising in gas sensor applications due to their compositional flexibility and unique 2D-interlayer channel for gas diffusion and adsorption. This work demonstrates highly porous hierarchical LDHs containing Mg and Al (MgAl-LDHs) for ethanol sensing at room temperature. These MgAl-LDHs, with unique flower-like hierarchical structure and mesoporous interlayer, were synthesized hydrothermally using sodium dodecyl sulfate as soft template as well as intercalating agent.

Ultrasensitive Silicon Nanowire Sensor Developed by a Special Ag Modification Process for Rapid NH Detection.

Surface functionalization is very effective in enhancing sensing properties of a chemiresistive gas sensor. In this work, we develop a novel and cost-effective process to prepare Ag-modified silicon nanowire (SiNW) sensors and further suggest a resistance effect model to clarify the enhanced sensing mechanism of Ag-modified SiNWs. The SiNWs were formed via metal-assisted chemical etching (MACE), and the Ag nanoparticle (NP) modification was achieved in situ based on the MACE-produced Ag dendrites by involving a crucial anisotropic postetching of TMAH.

Expression profiles of a cytoplasmic male sterile line of Gossypium harknessii and its fertility restorer and maintainer lines revealed by RNA-Seq.

The Gossypium harknessii background cytoplasmic male sterility (CMS) system has been used in cotton hybrid breeding in China. However, the mechanism underlying pollen abortion and fertility restoration in CMS remains to be determined. In this study, we used RNA-seq to identify critical genes and pathways associated with CMS in G.