This study aims to investigate the effectiveness of mind mapping in the standardized training and education of internal medicine resident physicians in nephrology. Sixty trainees undergoing rotations in the Nephrology Department at Chengdu University Affiliated Hospital between January 2021 and December 2023 were randomly assigned to control and observation groups, each comprising 30 trainees. The observation group received mind mapping teaching, while the control group received traditional teaching methods.
View Article and Find Full Text PDFOwing to their high sensitivity across a wide stress range, mechanical reliability, and rapid response time, flexible polymer foam piezoresistive sensors have been extensively used in various fields. The reliable application of these sensors under harsh environments, however, is severely limited by structural devastation and poor interfacial bonding between polymers and conductive nanoparticles. To address the above issues, robust MXene/CNT nanocoatings on the foam surface, where the chemical assembly of MXene nanosheets and the physical anchoring of CNTs lead to strong interfacial bonding, are designed and described, which endows foams with structural reliability and unexpected multi-functionalities without compromising their instinct properties.
View Article and Find Full Text PDFHuman activities, intensified urbanization and climate changes altered source and quantity of dissolved organic matter (DOM), complicating its interaction with phytoplankton in aquatic ecosystems. However, relationship between DOM and phytoplankton in urban lakes strongly disturbed by human activities was still unclear. Thus, a whole-year sampling campaign was conducted in the Tangxun Lake, China's largest urban lake, to reveal the interaction between DOM and phytoplankton.
View Article and Find Full Text PDFMethods: We recruited 58 MA-dependent young adult females from a compulsory isolation drug rehabilitation center in Sichuan Province and randomly divided them into an MBRP group (n = 29) and a control group (n = 29) according to their degree of psychological craving. The MBRP group received 2 hours of MBRP training twice a week for 4 weeks, alongside routine treatment at the drug rehabilitation center. Meanwhile, the control group solely received routine treatment at the drug rehabilitation center without any additional interventions.
View Article and Find Full Text PDF-Alkyl dithiocarbamates, as an important class of sulfur-containing compounds, play pivotal roles in diverse fields, yet methods for the synthesis that start from simple, readily available feedstocks and exhibit mild conditions and structurally diverse products are scarce. In this work, we developed an efficient approach for the synthesis of various -alkyl dithiocarbamates via visible-light photocatalysis with readily available and structurally diverse alkyl carboxylic acids (primary, secondary, and tertiary acids, amino acids, etc.) and disulfide tetraalkylthiuram as the starting materials.
View Article and Find Full Text PDFClin Neurol Neurosurg
November 2024
Indian J Otolaryngol Head Neck Surg
August 2024
Unlabelled: Primary cranial meningioma is extremely rare and only rarely described in clinical practice, as is primary sinus ectopic meningioma. We detailed the surgical management of a female patient, aged 83, who had a primary meningioma of the sphenoid sinus. This uncommon clinical entity was the subject of a study of the literature, and its prognosis was summarized.
View Article and Find Full Text PDFBackground: Coronary heart disease (CHD) is the leading cause of death in the world. There are some decision-making conflicts in the management of chest pain, treatment methods, stent selection, and other aspects due to the unstable condition of CHD in the treatment stage. Although using decision aids to facilitate shared decision-making (SDM) contributes to high-quality decision-making, it has not been evaluated in the field of CHD.
View Article and Find Full Text PDFThe valorization of electroplating sludge (ES) for high added value presents greater economic and environmental benefits than conventional treatment methods such as thermal processing, solidification, and landfill. Inspired by the mechanism of chemical looping combustion (CLC), this study developed a novel cost-effective method for denitrification by preparing FeNi-OCs from ES to achieve the synergistic reduction of CO and NO emissions. The phase structure, micromorphology, and valence state changes of the FeNi-OC catalyst during the CO-catalyzed reduction of NO and the pathway for catalytic denitrification using FeNi-OCs were analyzed.
View Article and Find Full Text PDFYing Yong Sheng Tai Xue Bao
January 2024
Long-term occupation of coal gangue dumping sites (CGDS) may destroy ecological environment of nearby area. However, how the CGDS affects the distribution pattern of soil seed banks and vegetation in the nearby area is not clear. In this study, we investigated soil seed bank and vegetation at different distances from the second CGDS of Yangchangwan in Ningdong mining area, Lingwu, Ningxia.
View Article and Find Full Text PDFA method for the selective construction of S-N/C(sp)-S bonds using -substituted -thiocarbamates and indoles as substrates is reported. This protocol features good atom utilization, mild conditions, short reaction time, and wide substrate scope, which can provide a convenient path for the functionalization of indoles. In addition, the reaction could be scaled up on gram scale, showing potential application value in industry synthesis.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
February 2024
Aberrant lysine lactylation (Kla) is associated with various diseases which are caused by excessive glycolysis metabolism. However, the regulatory molecules and downstream protein targets of Kla remain largely unclear. Here, we observed a global Kla abundance profile in colorectal cancer (CRC) that negatively correlates with prognosis.
View Article and Find Full Text PDFIntroduction: Membrane-associated guanylate kinase with an inverted domain structure-1 (MAGI1) is dysregulated in diabetes; however, its role in diabetic nephropathy (DN) remains unclear. In this study, we determined the function and associated mechanisms of MAGI1 in DN.
Methods: Serum samples from 28 patients with DN and 28 normal volunteers were collected.
Hydraulic fracturing using micro-particles is an effective technology in the petroleum industry since the particles facilitate crack propagation of the shale layer, creating pathways for oil and gas. A new kind of polymer-coated ceramsite particles (PCP) was generated. The friction and wear properties of the particles under different loads and speeds were also studied.
View Article and Find Full Text PDFTuna cooking liquid has unpleasant aroma. In our previous studies, JGM9-1 and RP26 demonstrated the ability to degrade this unpleasant aroma. However, the mechanism of microbial deodorization remains unclear.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
January 2024
Micro-arc oxidation (MAO) coatings containing 2.86 wt%, 5.83 wt% and 8.
View Article and Find Full Text PDFThe coordinated development of urban quality and technology innovation is an important element of China's technology innovation development strategy in the new era. Based on entropy TOPSIS, coupling coordination models, the gravity center and standard deviation ellipse method, the geographic probe, the GWR, and other methods, we explore the spatial variation and influencing factors of the coupling coordination relationship between urban quality and technology innovation in the Guangdong-Hong Kong-Macao Greater Bay Area from 2011 to 2020. It is found that: (1) the spatial distribution of the coupling coordination shows a characteristic of "high in the middle and low in the surroundings," and (2) the level of benign interaction in the central region is becoming more prominent.
View Article and Find Full Text PDFJ Colloid Interface Sci
November 2023
Hypothesis: Most droplets on high-efficiency condensing surfaces have radii of less than 100 μm, but conventional droplet transport methods (such as wettability-gradient surfaces and structural-curvature-gradient surfaces) that rely on the unbalanced force of three-phase lines can only transport millimeter-sized droplets efficiently. Regulating high-speed directional transport of condensate droplets is still challenging. Therefore, we present a method for condensate droplet transportation, based on the reaction force of the superhydrophobic saw-tooth surfaces to the liquid bridge, the condensate droplets could be transported at high speed and over long distances.
View Article and Find Full Text PDFObjective: In this study, we aimed to decipher the gut microbiome (GM) and serum metabolic characteristic of individuals at high risk for rheumatoid arthritis (RA) and to investigate the causative effect of GM on the mucosal immune system and its involvement in the pathogenesis of arthritis.
Methods: Fecal samples were collected from 38 healthy individuals and 53 high-risk RA individuals with anti-citrullinated protein antibody (ACPA) positivity (Pre-RA), 12 of 53 Pre-RA individuals developed RA within 5 years of follow-up. The differences in intestinal microbial composition between the healthy controls and Pre-RA individuals or among Pre-RA subgroups were identified by 16S ribosomal RNA sequencing.
Objective: To study the brain network mechanism of cognitive control in the elderly with brain aging.
Materials And Methods: 21 normal young people and 20 elderly people were included in this study. Mini-mental State Examination and functional near-infrared spectroscopy (fNIRS) synchronous judgment test (including forward tests and reverse judgment tests) were performed on all subjects.
Malignant glioma is the most frequent primary tumor of the central nervous system. PDCL3 is a member of the phosducin-like protein family, and its imbalance has been shown to be associated with several human diseases. However, the underlying role of PDCL3 in human malignant cancers, especially in malignant gliomas, is unclear.
View Article and Find Full Text PDFBackground: Recent studies have demonstrated that glioma-associated mesenchymal stem cells (GA-MSCs) are implicated in the regulation of glioma malignant progression. However, the prognostic value of GA-MSCs has not been comprehensively explored in glioma.
Methods: We extracted GA-MSCs from glioma tissues, established intracranial xenograft models in nude mice, and obtained GA-MSC-related genes (GA-MSCRGs) by using microarrays.
Accurate communication between fibroblasts and keratinocytes is crucial for diabetic wound healing. Extracellular vesicles are being explored as essential mediators of intercellular communication in the skin. However, the mechanisms underlying wound healing mediated by fibroblast-derived extracellular vesicles (Fib-EVs) remain unclear.
View Article and Find Full Text PDFGlioma is a highly common pathological brain tumor. Misfolded protein response, which is strongly associated with the growth of cancerous tumors, is mediated by the gene, endoplasmic reticulum degradation-enhancing alpha-mannosidase-like protein 2. However, this gene has not been linked to glioma.
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