Surface Modification of Graphene Oxide for Fast Removal of Per- and Polyfluoroalkyl Substances (PFAS) Mixtures from River Water.

Per- and polyfluoroalkyl substances (PFAS) make up a diverse group of industrially derived organic chemicals that are of significant concern due to their detrimental effects on human health and ecosystems. Although other technologies are available for removing PFAS, adsorption remains a viable and effective method. Accordingly, the current study reported a novel type of graphene oxide (GO)-based adsorbent and tested their removal performance toward removing PFAS from water.

Nicotinamide riboside ameliorates high-fructose-induced lipid metabolism disorder in mice improving FGF21 resistance in the liver and white adipose tissue.

Fructose has been reported to acutely elevate the circulating fibroblast growth factor 21 (FGF21) levels, which ultimately causes FGF21 resistance. FGF21 resistance is suggested to result in lipid metabolism disorder. Nicotinamide riboside (NR) can alleviate lipid metabolism disorder in mice.

Folic acid ameliorates alcohol-induced liver injury gut-liver axis homeostasis.

The gut-liver axis (GLA) plays an important role in the development of alcohol-induced liver injury. Alcohol consumption is typically associated with folic acid deficiency. However, no clear evidence has confirmed the effect of folic acid supplementation on alcohol-induced liver injury GLA homeostasis.

Garlic oil alleviates high triglyceride levels in alcohol-exposed rats by inhibiting liver oxidative stress and regulating the intestinal barrier and intestinal flora.

Garlic oil (GO) is a kind of natural extract extracted from garlic, which has strong antioxidant activity. This study elucidates the protective mechanism of GO against alcohol-induced high triglyceride levels. Sixty male Sprague Dawley rats were assigned to five groups, including a control group (CON), a model group (MOD) treated with alcohol 56% v/v at 8 ml kg day for 2 weeks then 10 ml kg day for 8 weeks, a low-dose GO group (GO-L) given GO at 20 mg kg day, a high-dose GO group (GO-H) given GO at 40 mg kg day, and a positive group (POS) given diammonium glycyrrhizinate at 200 mg kg day.

Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.

Folic acid, as a key source of methyl donor in DNA methylation, has been proved to play a beneficial role in inflammation modulation, which is usually impaired in alcoholic liver disease (ALD). However, the role of folic acid in alcoholic liver inflammation and injury remain elusive. In this study, we sought to uncover the potential protective mechanism by which folic acid ameliorates alcoholic liver injury.

Attention-Aware Residual Network Based Manifold Learning for White Blood Cells Classification.

The classification of six types of white blood cells (WBCs) is considered essential for leukemia diagnosis, while the classification is labor-intensive and strict with the clinical experience. To relieve the complicated process with an efficient and automatic method, we propose the Attention-aware Residual Network based Manifold Learning model (ARML) to classify WBCs. The proposed ARML model leverages the adaptive attention-aware residual learning to exploit the category-relevant image-level features and strengthen the first-order feature representation ability.

Effect of scale inhibitors on the structure and morphology of CaCO crystal electrochemically deposited on TA1 alloy.

The deposition of CaCO scale in circulating cooling water on metal surface is a major concern in industry. This paper focuses on the feasibility of electrochemical methods to study the scale inhibition performance of 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) and 2-phosphonobutane-1,2,4-tricarboxylic acid (PBTCA), Polyacrylic Acid (PAA), including linear sweep voltammetry, chronoamperometry, and electrochemical impedance spectroscopy (EIS). In addition, the coverage, morphology and structure of deposited CaCO crystal on titanium alloy surface in the absence and presence of inhibitors were investigated by X-ray diffraction (XRD) and scanning electron microscopy (SEM).