Fabrication and performance evaluation of a design for an extended depth-of-focus intraocular lens based on an improved sinusoidal profile.

This study presents the fabrication and evaluation of a sinusoidal extended depth-of-focus (EDoF) intraocular lens (IOL) based on our previously proposed design approach. The power, through-focus MTF, and surface profile were measured using commercial instruments. Through-focus images of a United States Air Force (USAF) 1951 resolution target formed by the fabricated IOL were compared with Symfony and AR40E under monochromatic and polychromatic light using optical bench testing.

Establishment and validation of a diagnostic model for diabetic nephropathy in type 2 diabetes mellitus.

Purpose: There are few studies on the establishment of diagnostic models for diabetic nephropathy (DN) in in type 2 diabetes mellitus (T2DM) patients based on biomarkers. This study was to establish a model for diagnosing DN in T2DM.

Methods: In this cross-sectional study, data were collected from the Second Hospital of Shijiazhuang between August 2018 to March 2021.

Approach to the design of different types of intraocular lenses based on an improved sinusoidal profile.

An approach is presented to design different types of Intraocular lenses (IOLs) with a uniform optimization algorithm. An improved sinusoidal phase function is proposed to realize adjustable energy allocations in different diffractive orders according to the design aims. By setting specific optimization goals, different types of IOLs can be designed using the same optimization algorithm.

Comparison of wavefront aberrations in the object and image spaces using wide-field individual eye models.

Wavefront aberrations in the image space are critical for visual perception, though the clinical available instruments usually give the wavefront aberrations in the object space. This study aims to compare the aberrations in the object and image spaces. With the measured wavefront aberrations over the horizontal and vertical ±15° visual fields, the in-going and out-going wide-field individual myopic eye models were constructed to obtain the wavefront aberrations in the object and image spaces of the same eye over ±45° horizontal and vertical visual fields.

Nomogram for prediction of diabetic retinopathy in patients with type 2 diabetes mellitus: A retrospective study.

Objective: To develop a nomogram for the risk of diabetic retinopathy (DR) among type 2 diabetes mellitus (T2DM).

Methods: Questionnaires, physical examinations and biochemical tests were performed on 5900 T2DM patients in the Second Hospital of Shijiazhuang. The least absolute shrinkage and selection operator regression was used to optimize feature selection, and the importance of selected features was analyzed by random forest.