Argatroban and Menadione exert protective effects in ultraviolet-irradiated skin inflammation: A transcriptomic analysis based on identification of iron overload related biomarkers.

Ultraviolet light (UV) can cause serious damage to human skin. The inflammatory reaction arising from repeated UV exposure leads to severe skin lesions and even promotes photo-carcinogenesis. Iron overload is featured by excessive iron intake and deposition and will promote inflammatory response inside cells.

Recent Advances in Toxicity Prediction: Applications of Deep Graph Learning.

The development of new drugs is time-consuming and expensive, and as such, accurately predicting the potential toxicity of a drug candidate is crucial in ensuring its safety and efficacy. Recently, deep graph learning has become prevalent in this field due to its computational power and cost efficiency. Many novel deep graph learning methods aid toxicity prediction and further prompt drug development.

Complete plastid genome of Maxim. (Gentianaceae) and phylogenetic analysis.

The complete plastid genome of Maxim., belonging to the most species-rich section in , was determined and analyzed in this study. It has a circular-mapping molecular with the length of 131,856 bp, the shortest one among all available plastomes.