Publications by authors named "Yuwan Qi"
Article Synopsis
- Microglia are key immune cells in the central nervous system, crucial for brain development and maintaining neural connections by responding to environmental changes.
- They interact with various brain cells to perform functions like synapse pruning, neurogenesis, and maintaining the blood-brain barrier, demonstrating their role in both health and disease.
- The review discusses specific signals from neurons that guide microglial responses during brain development, highlighting their potential in treating nervous system diseases linked to synaptic dysfunction.
Adhesion G protein-coupled receptors (aGPCRs) are the second largest diverse group within the GPCR superfamily, which play critical roles in many physiological and pathological processes through cell-cell and cell-extracellular matrix interactions. The adhesion GPCR Adgrg6, also known as GPR126, is one of the better-characterized aGPCRs. GPR126 was previously found to have critical developmental roles in Schwann cell maturation and its mediated myelination in the peripheral nervous system in both zebrafish and mammals.
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