Re-emergence and influencing factors of mountain-type zoonotic visceral leishmaniasis in the extension region of Loess Plateau, China.

Objective: To understand the epidemiological distribution characteristics of mountain-type zoonotic visceral leishmaniasis (MT-ZVL) in Yangquan City, Shanxi Province, China, from 2006 to 2021, to explore the influencing factors leading to the re-emergence of the epidemic, and to provide a basis for the formulation of targeted control strategies.

Methods: Case information spanning from 2006 to 2021 in Yangquan City was collected for a retrospective case-control study conducted from June to September 2022. A 1:3 matched ratio was employed.

The genetic diversity of Oncomelania hupensis robertsoni, intermediate hosts of Schistosoma japonicum in hilly regions of China, using microsatellite markers.

Background: The elimination of schistosomiasis remains a challenging task, with current measures primarily focused on the monitoring and control of Oncomelania hupensis (O. hupensis) snail, the sole intermediate host of Schistosome japonicum. Given the emerging, re-emerging, and persistent habitats of snails, understanding their genetic diversity might be essential for their successful monitoring and control.

Field validation of different intervention modes for the potential transmission risk of schistosomiasis during post-transmission interruption phase.

Objective: Precision interventions have been proposed in transmission-interrupted areas to further reduce the potential transmission risk of schistosomiasis. This study aimed to evaluate the effects of different interventions modes for potential transmission risk control.

Methods: Three groups of schistosomiasis-endemic villages were selected in Jiangling county, Hubei province.

Recognizing and monitoring infectious sources of schistosomiasis by developing deep learning models with high-resolution remote sensing images.

Background: China is progressing towards the goal of schistosomiasis elimination, but there are still some problems, such as difficult management of infection source and snail control. This study aimed to develop deep learning models with high-resolution remote sensing images for recognizing and monitoring livestock bovine, which is an intermediate source of Schistosoma japonicum infection, and to evaluate the effectiveness of the models for real-world application.

Methods: The dataset of livestock bovine's spatial distribution was collected from the Chinese National Platform for Common Geospatial Information Services.

Transmission Risk Predicting for Schistosomiasis in Mainland China by Exploring Ensemble Ecological Niche Modeling.

Schistosomiasis caused by is one of the major neglected tropical diseases worldwide. The snail is the only intermediate host of which is recognized as an indicator of the schistosomias occurrence. In order to evaluate the risk of schistosomiasis in China, this work investigate the potential geographical distribution of host snail habitus by developing an ensemble ecological niche model with reference to the suitable environmental factors.

Establishment of an indicator framework for the transmission risk of the mountain-type zoonotic visceral leishmaniasis based on the Delphi-entropy weight method.

Background: Visceral leishmaniasis (VL) is one of the most important neglected tropical diseases. Although VL was controlled in several regions of China during the last century, the mountain-type zoonotic visceral leishmaniasis (MT-ZVL) has reemerged in the hilly areas of China in recent decades. The purpose of this study was to construct an indicator framework for assessing the risk of the MT-ZVL in China, and to provide guidance for preventing disease.

Epidemiological features and spatial-temporal clustering of visceral leishmaniasis in mainland China from 2019 to 2021.

Background: Visceral leishmaniasis (VL) is a serious vector-borne disease in central and western China. In recent years, the number of VL cases increased gradually, particularly the mountain-type zoonotic visceral leishmaniasis (MT-ZVL). This study clarified the epidemiological features and spatial-temporal clustering of VL in China between 2019 and 2021, identified the risk areas for VL transmission, and provided scientific evidence for the prevention and control of VL.

Assessment on the Diagnostic Capacity for Parasitic Diseases of Health Facilities - China, 2019.

What Is Already Known About This Topic?: Morbidity and prevalence of several major parasitic diseases have been declining in China. To reduce the disease burden of parasitic diseases and protect public health security, conducting accurate diagnoses following timely treatment is important.

What Is Added By This Report?: In the national competition held in 2019, the overall accuracy rates of participants for theoretical knowledge and slides interpretation for parasitic diseases were 80.

Spatio-temporal clustering of Mountain-type Zoonotic Visceral Leishmaniasis in China between 2015 and 2019.

With several decades of concerted control efforts, visceral leishmaniasis(VL) eradication had almost been achieved in China. However, VL cases continue to be detected in parts of western China recent years. Using data of reported cases, this study aimed to investigate the epidemiology and spatio⁃temporal distribution, of mountain-type zoonotic visceral leishmaniasis (MT-ZVL) in China between the years 2015 and 2019.

Potential impact of flooding on schistosomiasis in Poyang Lake regions based on multi-source remote sensing images.

Background: Flooding is considered to be one of the most important factors contributing to the rebound of Oncomelania hupensis, a small tropical freshwater snail and the only intermediate host of Schistosoma japonicum, in endemic foci. The aim of this study was to assess the risk of intestinal schistosomiasis transmission impacted by flooding in the region around Poyang Lake using multi-source remote sensing images.

Methods: Normalized Difference Vegetation Index (NDVI) data collected by the Landsat 8 satellite were used as an ecological and geographical suitability indicator of O.

Construction and application of surveillance and response systems for parasitic diseases in China, led by NIPD-CTDR.

Parasitic diseases have been widely epidemic in China with a long history. Great endeavours made in past 70 years led to significant decrease in morbidity and mortablity caused by several major parasitic diseases, while challenges existed to eliminate parasitic diseases. Surveillance-response system has play a crucial role in identifying public health problems, ascertaining the distribution and epidemic dynamics, discovering outbreaks and epidemic anomalies, evaluating the effects of on-site intervention activities and identifying risk factors.

Temporal transcriptome change of revealed by invasion.

Background: The freshwater snail is the obligate intermediate host for in China. Transcriptomic examination of snail-schistosome interactions can provide valuable information of host response at physiological and immune levels.

Methods: To investigate -induced changes in gene expression, we utilized high-throughput sequencing to identify transcripts that were differentially expressed between infected snails and their uninfected controls at two key time-point, Day 7 and Day 30 after challenge.

Intestinal microbiome profiles in Oncomelania hupensis in mainland China.

Oncomelania hupensis plays a significant role in the transmission of schistosomiasis japonica, which remains a major public health concern in China. Understanding the biological characteristics of O. hupensis is a prerequisite for its control; however, there are currently no studies investigating the intestinal microbiota of the O.

[Spatial - temporal clustering analysis of schistosomiasis transmission risk in Yunnan Province from 2004 to 2015].

Objective: To explore the spatial-temporal clustering distribution of schistosomiasis transmission risk in Yunnan Province from 2004 to 2015, so as to provide scientific evidence for the future schistosomiasis control and consolidation of the control achievements.

Methods: All data pertaining to endemic situation of human and bovine schistosomiasis and snail survey at a township level in Yunnan Province from 2004 to 2015 were collected. A descriptive epidemiological method and Joinpoint model were used to describe the changing trends of infections in humans, bovine and snails, and the hotspots and clusters of schistosomiasis transmission risk were identified using spatial autocorrelation analysis, hotspots analysis and retrospective space-time scan statistic in Yunnan Province from 2004 to 2015.

High-resolution remote sensing-based spatial modeling for the prediction of potential risk areas of schistosomiasis in the Dongting Lake area, China.

The geographical distribution of snail (i.e., the intermediate host of schistosomiasis) is consistent with that of endemic areas.

High-resolution remote sensing-based spatial modeling for the prediction of potential risk areas of schistosomiasis in the Dongting Lake area, China.

The geographical distribution of snail (i.e., the intermediate host of schistosomiasis) is consistent with that of endemic areas.

Assessing competence for helminthiases: A lesson learnt from national contest of parasitic diseases in China in 2012-2016.

This study aimed to assess the competency of health professionals on helminthiasis control in China. The assessment system comprised of two parts, one being the parasitological knowledge test and the other a technical skills assessment. The knowledge test mainly examined morphology, epidemiology, life history and diagnosis of common and important parasites.

[Assessment of ability of professionals in parasitic disease control and prevention techniques in China, 2017].

Objective: To understand the professional theory, prevention and control practice, experimental diagnosis and other technical skills of parasitic diseases among technicians of all levels of disease control and prevention institutions, so as to provide the evidence for strengthening the capacity building of Chinese professional personnel.

Methods: According to the method of recommendation at all levels, the subjects from disease control and prevention institutions at province, prefecture or county levels were chosen to assess the theory of parasitic diseases and test operation skills by using the method of answering the questions together with on-site operations in China. A database was built consisting of subjects' basic information and assessment scores.

[Transmission risk matrix assessment of imported leishmaniasis in China].

Objective: To assess the risk of imported leishmaniasis in China, offering scientific evidences for leishmaniasis prevention and control.

Methods: The expert consultation method was used to establish a risk index system, and the risk matrix was used to evaluate the risk scales of leishmaniasis.

Results: This risk assessment indicator system included 3 first-grade indexes and 13 second-grade indexes to the aspect of risk probability.

[Epidemiological characteristics of echinococcosis death cases in China from 2008 to 2016].

Objective: To understand the epidemiological characteristics of death cases of echinococcosis in China from 2008 to 2016, so as to provide an important reference for the prevention and control of echinococcosis.

Methods: The death information registration and management system data were selected to analyze the epidemiological characteristics of the death cases of echinococcosis. The data were analyzed by SPSS 21.