Publications by authors named "Yuval Orsher"
Numerous studies have identified traveling waves in the cortex and suggested they play important roles in brain processing. These waves are most often measured using macroscopic methods that are unable to assess the local spiking activity underlying wave dynamics. Here, we investigated the possibility that waves may not be traveling at the single neuron scale.
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- Notch signaling is crucial for coordinating cell differentiation across various organisms, but the impact of receptor and ligand distribution on signaling is not well understood.
- By using live-cell imaging and mathematical modeling, researchers studied the behavior of the Notch ligand Delta-like 1 (Dll1) in mammalian cells, revealing significant variability in its diffusion rates among different cells.
- The findings indicate that the dynamics of membrane distribution and cell shape can significantly influence cell-to-cell signaling, highlighting the importance of these factors in biological processes.