Publications by Yuuya Fujii

Publications by authors named "Yuuya Fujii"

J Biosci Bioeng

April 2024

Lipomyces starkeyi is a yeast with the ability to produce triacylglycerides (TAGs) using various carbon sources, making it valuable for industrial applications.
Researchers found that the gene LsSPT23, when expressed at high levels, boosts TAG production by activating key biosynthesis pathways.
Deleting the negative regulator LsSNF1 increased TAG production by enhancing metabolic pathways and carbon source utilization, revealing its crucial role in lipid synthesis in L. starkeyi.*

- Yuuya Fujii's recent research explores the genetic manipulation of the oleaginous yeast Lipomyces starkeyi to enhance lipid accumulation, crucial for its industrial applications in biotechnology.
- The study specifically investigates the deletion of the gene LsSNF1, which leads to increased synthesis of intracellular triacylglycerides (TAGs) by upregulating key metabolic pathways.
- Findings suggest that the transcriptional regulator LsSpt23p plays a significant role in this process, highlighting potential targets for optimizing lipid production in yeast for biofuel and other applications.