Factors associated with incomplete adherence to integrase strand transfer inhibitor-containing single-tablet regimen among Japanese people living with HIV.

Background: People living with human immunodeficiency virus (PLWH) require high rates of medication adherence to antiretroviral therapy (ART) for a successful treatment outcome. Understanding the factors associated with incomplete adherence among those receiving integrase strand transfer inhibitor-containing single-tablet regimens (INSTI-STRs) is crucial for improving treatment outcomes. This study aimed to identify the factors contributing to incomplete ART adherence among Japanese PLWH receiving INSTI-STRs.

Factors associated with patient satisfaction with antiretroviral therapy in Japan: A cross-sectional, multicenter study.

Background: Current antiretroviral therapy (ART) regimens are highly effective; therefore, to differentiate between various regimens, considering patient-reported outcomes is essential. This study aimed to assess patient satisfaction with their current ART regimens and investigate factors associated with the Human Immunodeficiency Virus Treatment Satisfaction Questionnaire: Status (HIVTSQs) score.

Methods: This cross-sectional, multicenter study was conducted in Japan between April and December 2021.

Assessment of Multidimensional Health Care Parameters Among Adults in Japan for Developing a Virtual Human Generative Model: Protocol for a Cross-sectional Study.

Background: Human health status can be measured on the basis of many different parameters. Statistical relationships among these different health parameters will enable several possible health care applications and an approximation of the current health status of individuals, which will allow for more personalized and preventive health care by informing the potential risks and developing personalized interventions. Furthermore, a better understanding of the modifiable risk factors related to lifestyle, diet, and physical activity will facilitate the design of optimal treatment approaches for individuals.

Cytokeratin 5/6 expression in pT1 bladder cancer predicts intravesical recurrence in patients treated with bacillus Calmette-Guérin instillation.

Bacillus Calmette-Guérin (BCG) instillation is the gold standard for the treatment of patients with pT1 bladder cancer but causes severe adverse effects. Few predictive factors have been established for intravesical recurrence and/or stage progression in bladder cancer. We analysed 138 patients who underwent transurethral resection of bladder tumour and were pathologically confirmed to have stage pT1 bladder cancer.

Causes of anxiety among teachers giving face-to-face lessons after the reopening of schools during the COVID-19 pandemic: a cross-sectional study.

Background: Coronavirus infections are spreading rapidly worldwide, and primary and middle schools are closed in many countries. After the state of emergency was lifted in Japan, schools have reopened, and teachers are conducting face-to-face classes while maintaining safety precautions. This study aimed to assess the factors contributing to infection-related anxiety and educational anxiety among teachers conducting face-to-face classes during the COVID-19 pandemic after schools reopened.

Pathological and Virological Studies of p16-Positive Oropharyngeal Carcinoma with a Good Response to Neoadjuvant Chemotherapy.

Human papillomavirus (HPV)-related, p16-positive oropharyngeal carcinoma is considered to be sensitive to anticancer drugs, and the standard treatment is therefore chemoradiotherapy, rather than surgery, especially for aggressive disease. However, with this higher sensitivity, chemotherapy alone may achieve a pathological complete response (CR), making radiation therapy unnecessary. A 46-year-old man with p16-positive squamous cell carcinoma (SCC) of the lateral oropharynx (palatine tonsil) underwent neoadjuvant chemotherapy.

[A case of negative pressure pulmonary hemorrhage associated with upper-airway obstruction due to a giant vocal cord nodule].

A 68-year-old woman was brought by ambulance because of sudden choking sensation and dyspnea after coughing. A physical examination showed hoarseness and blood-stained sputum. A chest computed tomography (CT) showed bilateral diffusely-distributed ground-glass opacity.

Stabilization of long-lived metastable state in long alkylated spin-crossover cobalt(II) compound.

The A mixed crystal compound [Co(0.8)Fe(0.2)(C16-terpy)(2)](BF(4))(2) (2) (C16-terpy is 4'-hexadecyloxy-2,2':6',2''-terpyridine) with long alkyl chains was prepared by mixing [Co(C16-terpy)(2)](BF(4))(2) (1), which exhibits unique magnetic behavior, and the diamagnetic iron(II) compound [Fe(C16-terpy)(2)](BF(4))(2) (3).

Bis(1H-imidazole-κN){2,2'-[propane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato-κO,N,N',O'}iron(III) perchlorate.

The title compound, [Fe(C(17)H(16)N(2)O(2))(C(3)H(4)N(2))(2)]ClO(4), consists of monomeric [Fe(salmen)(HIm)(2)](+) cations {salmen is the 2,2'-[propane-1,2-diylbis(nitrilo-methyl-idyne)]diphen-olate dianion and HIm is 1H-imiazole} and perchlorate anions. In the cation, the Fe(3+) ion is octahedrally coordinated by two N atoms and two O atoms from a tetra-dentate salmen anion and two N atoms from two Him mol-ecules. These ligands are coordinated to the iron ion in a direction perpendicular to the [Fe(salmen)](+) coordination plane.

Bis[2-(8-quinolylimino-meth-yl)phenolato-κN,N',O]iron(III) azide.

The title compound, [Fe(C(16)H(11)N(2)O)(2)]N(3), consists of a [Fe(qsal)(2)](+) cation [Hqsal = N-(8-quinol-yl)salicylaldimine] and an azide anion. The Fe(III) ion, lying on a twofold rotation axis, is coordinated by four N atoms and two O atoms from two tridentate qsal ligands in an octa-hedral geometry. The mol-ecules are connected into a three-dimensional network by inter-molecular C-H⋯N and C-H⋯O inter-actions.

High facial selectivity observed in amine coordination to chiral oxazaborolidinones.

A variety of 1,3,2-oxazaborolidin-5-ones (OXB) derived from N-sulfonyl amino acids exhibit a high top-face selectivity in complexation with pyridines under thermodynamically controlled conditions.