Publications by authors named "Yuuki Kyoda"
[Experience with gemcitabine monotherapy in three patients with metastatic urothelial carcinoma].
Nihon Hinyokika Gakkai Zasshi
September 2011
Article Synopsis
- Three patients with metastatic urothelial carcinoma were treated with gemcitabine (GEM) monotherapy, showing varied responses to the treatment.
- A 78-year-old male experienced progression after 8 cycles, while a 68-year-old male maintained stable disease after 9 cycles of GEM post-first-line therapy.
- A 70-year-old female had progressive disease after 3 cycles, highlighting that GEM can be adapted for patients with severe renal insufficiency, but results may differ between individuals.
Article Synopsis
- A 67-year-old man undergoing peritoneal dialysis for kidney disease was treated with valacyclovir for herpes zoster but developed hallucinations due to neurotoxicity from an overdose.
- After hospitalization and monitoring of his acyclovir levels, his symptoms resolved within a week without additional treatment beyond continuing dialysis.
- The case suggests that adjusting the valacyclovir dosage based on renal function is crucial, and hemodialysis may be necessary for patients with severe complications.
Objectives: We analyzed the efficacy of additional antiandrogens as second- and third-line treatments after the failure of initial androgen deprivation monotherapy.
Methods: This retrospective study included 53 patients with advanced prostate cancer initially treated with androgen deprivation monotherapy alone. An antiandrogen was added to androgen deprivation monotherapy as the second-line treatment after the failure of the initial androgen deprivation monotherapy.
Article Synopsis
- A study at Sapporo Medical University Hospital examined the impact of changes in surgical wound management on the incidence of surgical site infections (SSI) after radical cystectomy over two time periods: 1996-2003 (Group A) and 2004-2007 (Group B).
- The results showed a significant decrease in SSI from 32.1% in Group A to 18.2% in Group B, following modifications to suturing techniques and standardizing drain and dressing removal procedures.
- Despite the reduction in SSI rates, methicillin-resistant Staphylococcus aureus (MRSA) remained a prevalent infection in both groups; preoperative MRSA bacteriuria was identified as a key risk factor for developing SSI
A 67-year-old male had an innate fistular orifice at the scrotal skin. In spite of occasional pus discharge from the orifice, no treatment had been performed for the fistula because it improved spontaneously. Due to increasing pus discharge, the fistula was resected at a dermatology clinic, but a persistent fistula tract was confirmed postoperatively by MRI.
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