Publications by authors named "Yuuki Ishida"
[Diffuse infiltrating primary cerebellar glioma involving the brainstem: a case report].
Rinsho Shinkeigaku
November 2023
An 85-year-old woman was admitted to our hospital with unsteady gait, dizziness, nausea, and vomiting. MRI revealed characteristic abnormal signals in the bilateral cerebellar hemispheres. A brain biopsy was performed which confirmed a definitive histological diagnosis of diffuse glioma.
View Article and Find Full Text PDFBackground: Idiopathic spinal cord herniation (ISCH) is very rare. Some reports have described postoperative ventral cerebrospinal fluid (CSF) collections in patients with ISCH; however, such collections are asymptomatic in most patients, and there is no consensus regarding whether they are part of the natural history or a complication.
Observations: A 30-year-old man with ISCH underwent direct closure of a duplicated dura mater.
Article Synopsis
- - Anterior cervical foraminotomy is a surgical technique that aims to relieve nerve root pressure while preserving the movement of the spine and minimizing bone removal.
- - Balancing the need to preserve spinal motion and maximize nerve decompression requires a high level of skill and expertise in the procedure.
- - A strong understanding of anatomy and the ability to navigate a limited surgical space are critical for successfully accessing nerve roots during surgery.
Article Synopsis
- The study presents a method using a surface plasmon resonance (SPR) biosensor to assess how effectively different inhibitors prevent the breakdown of collagen IV by the enzyme cathepsin B.
- SPR signal changes showed that higher concentrations of inhibitors led to decreased enzyme activity, with a specific order of effectiveness for each inhibitor.
- The findings indicate that CA074 and Z-Phe-Phe-FMK primarily inhibit exopeptidase activity, while leupeptin is a stronger inhibitor of endopeptidase activity in cathepsin B.
The effects of orally administered sphingomyelin-based liposomes (SM-lipo) on muscle function were investigated in senescence-accelerated mice prone 1 (SAMP1) for the purpose of protection against or treatment of sarcopenia. SM-lipo were prepared by thin lipid-film hydration followed by extrusion. Their spherical shape was observed by transmission electron microscopy.
View Article and Find Full Text PDFEvaluation of cathepsin B activities for degrading collagen IV and heat-denatured collagen IV (gelatin) were performed by surface plasmon resonance (SPR) and circular dichroism (CD) measurements. The optimal pH of cathepsin B activity for degrading each substrate was around 4.0.
View Article and Find Full Text PDFThe junctional adhesion molecule (JAM) family is a key molecule in a process called transendothelial migration or diapedesis. Here, we report implications of JAM-C in cancer metastasis. We first determined the mRNA expression of JAMs in 19 kinds of cancer cell lines.
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