Identification of Rice Extract Components that Increase β-Glucocerebrosidase Levels in Human Epidermal Keratinocytes.

Rice miso contains many ingredients derived from rice and has been a valuable source of nutrition since ancient times. We found that the consumption of rice miso led to improvements in the moisture content of cheek stratum corneum, skin viscoelasticity, and skin texture. Further, rice miso extract was found to increase the mRNA expression and activity of β-glucocerebrosidase (β-GCase), an enzyme involved in ceramide synthesis in the stratum corneum, in cultures.