An RPA-CRISPR/Cas12a-assisted method for nucleic acid detection of Haemonchus contortus in sheep.

Haemonchus contortus (H. contortus), a highly pathogenic and blood-feeding nematode, could cause haemonchosis，resulting in tens of billions of dollars in production losses and significantly impacting the development of sheep husbandry. Rapid and accurate detection methods were particularly important for the prevention and control of haemonchosis.

Intelligent Flexible Pressure Sensors with Improved Sensing Range and Sensitivity Based on 3D-Graphene Patterning Induced by UV Laser.

Intelligent flexible sensors are an integral component of the next generation of consumer electronics. However, developing a flexible pressure sensing system that possesses both high sensitivity and a sensing range remains a key challenge in practical applications. Herein, a machine learning-assisted 3D laser-induced graphene (3D-LIG)/polydimethylsiloxane composite flexible pressure sensing system based on ultraviolet (UV) laser integrated fabrication was proposed.

Farnesoid X Receptor: Effective alleviation of rifampicin -induced liver injury.

Antituberculosis drugs induce pharmacologic cholestatic liver injury with long-term administration. Liver injury resulting from rifampicin is potentially related to the bile acid nuclear receptor Farnesoid X Receptor (FXR). To investigate this, cholestasis was induced in both wild-type (C57BL/6N) mice and FXR knockout (FXR-null) mice through administration of rifampicin (200 mg/kg) via gavage for 7 consecutive days.

Bile acid-microbiota crosstalk in hepatitis B virus infection.

Hepatitis B virus (HBV) is a hepatotropic non-cytopathic virus characterized by liver-specific gene expression. HBV infection highjacks bile acid metabolism, notably impairing bile acid uptake via sodium taurocholate cotransporting polypeptide (NTCP), which is a functional receptor for HBV entry. Concurrently, HBV infection induces changes in bile acid synthesis and the size of the bile acid pool.

The covariant structural and functional neuro-correlates of cognitive impairments in patients with end-stage renal diseases.

Introduction: Cognitive impairment (CI) is a common complication of end-stage renal disease (ESRD) that is associated with structural and functional changes in the brain. However, whether a joint structural and functional alteration pattern exists that is related to CI in ESRD is unclear.

Methods: In this study, instead of looking at brain structure and function separately, we aim to investigate the covariant characteristics of both functional and structural aspects.

Scholar Metrics Scraper (SMS): automated retrieval of citation and author data.

Academic departments, research clusters and evaluators analyze author and citation data to measure research impact and to support strategic planning. We created Scholar Metrics Scraper (SMS) to automate the retrieval of bibliometric data for a group of researchers. The project contains Jupyter notebooks that take a list of researchers as an input and exports a CSV file of citation metrics from Google Scholar (GS) to visualize the group's impact and collaboration.

The TICE Pathway: Mechanisms and Potential Clinical Applications.

Purpose Of Review: Transintestinal cholesterol excretion (TICE) is a non-biliary pathway that excretes excess cholesterol from the body through feces. This article focuses on the research progress of the TICE pathway in the last few years, including the discovery process of the TICE pathway, its molecular mechanism, and potential clinical applications.

Recent Findings: Cholesterol homeostasis is vital for cardiovascular diseases, stroke, and neurodegenerative diseases.

Multifunctional Actuator Based on Graphene/PDMS Composite Materials with Shape Programmable Configuration and High Photothermal Conversion Capability.

Photoresponsive smart actuators based on carbon materials are attracting increasing attention. However, the low content of carbon materials currently limits the development of carbon material actuators. In this work, we designed and prepared a multifunctional bilayer composite actuator with controllable structures and high photothermal conversion efficiency.

Case report: Ultrasound-guided multi-site electroacupuncture stimulation for a patient with spinal cord injury.

Introduction: Spinal cord injury causes permanent neurological deficits, which have devastating physical, social, and vocational consequences for patients and their families. Traditional Chinese medicine uses acupuncture to treat neuropathic pain and improve nerve conduction velocity. This treatment can also reduce peripheral nerve injury joint contracture and muscle atrophy in affected patients.

Evaporation and in-situ gelation induced porous hybrid film without template enhancing the performance of lithium ion battery separator.

The current commercialized polyethylene (PE) separator has poor wettability and thermal stability which will seriously restrict the electrochemical performance and affect the safety of lithium ion battery. Herein, a porous hybrid layer coated separator with high thermal stability, good electrochemical performance and improved wettability was prepared by a template-free method via the synergistic effect between tetraethoxysilane (TEOS) and aramid nano fibers (ANFs) during the evaporation of solvent and the in-situ gelation of TEOS. The results show that the porous hybrid coating layers can enhance the thermal stability, wettability and electrolyte uptake of the separators.

Hyper-Cross-Linked Polymers-Derived Porous Tubular Carbon Nanofibers@TiO toward a Wide-Band and Lightweight Microwave Absorbent at a Low Loading Content.

An enormous challenge exists in the achievement of one-dimensional (1D) dielectric carbon composite high-performance microwave absorbents at a low filling ratio. Porous/core-shell dual microstructures have been considered as the potential candidate for designing remarkable microwave absorbers with strong absorption and wide band. Herein, novel multiple-structured tubular carbon nanofibers@TiO (TCNFs@TiO) hybrids were constructed via the sequential steps of hydrolysis and pyrolysis.

The photoluminescence, field emission and femtosecond nonlinear absorption properties of Al-doped ZnO nanowires, nanobelts, and nanoplane-cone morphologies.

Al-doped ZnO (AZO) nanowires, nanobelts and nanoplane-cone nanostructures have been successfully synthesized. The structural, photoluminescence (PL) and field emission (FE) properties of AZO nanowires have been characterized. The dependence of the PL properties of AZO nanostructures excitation laser power in the range from 1 to 12 mW and temperature in the range of 10-273 K was discussed.

Characterizing scale-specific environmental factors affecting soil organic carbon along two landscape transects.

Soil organic carbon (SOC) is one of the most important soil properties affecting many other soil and environmental properties and processes. In order to understand and manage SOC effectively, it is important to identify the scale-specific main factors affecting SOC distributions, which in this study occurred in a watershed on the Loess Plateau. Two transects were selected that passed along the upper slopes on each side of the main gully of the Liudaogou watershed.

Dynamic rheological studies of poly(p-phenyleneterephthalamide) and carbon nanotube blends in sulfuric acid.

We have studied the dynamic scanning of liquid-crystalline (LC) poly(p-phenyleneterephthalamide) sulfuric acid (PPTA-H(2)SO(4)) solution, and its blend with single-walled carbon nanotubes (SWNTs), by using a flat plate rotational rheometer. The effects of weight concentration and molecular weight of PPTA, as well as operating temperature, on dynamic viscoelasticity of the PPTA-H(2)SO(4) LC solution system are discussed. The transition from a biphasic system to a single-phase LC occurs in the weight concentration range of SWNTs from 0.