Publications by authors named "Yuting Xia"

Introduction: With advancements in detection equipment and an increase in the frequency of examinations, thyroid nodules and goiter in children have garnered attention.

Objective: This study aims to determine the effects of high iodine and fluoride exposure on thyroid nodules and goiter in school-aged children.

Methods: We recruited children aged 8 to 12 from rural Jiangsu, China, based on the concentrations of iodine and fluoride in local drinking water and urine.

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  • Age-related bone loss in mice is linked to the buildup of senescent cells and reduced bone formation by osteoblasts, highlighting the significance of Matrix Gla protein (MGP) in this process.
  • Researchers created a specific type of mouse (Mgp cKO) to investigate MGP's role in bone health, finding that these mice had decreased bone volume and increased markers of cellular damage and aging.
  • The study suggests that MGP helps protect against osteoblast aging, and introducing recombinant human MGP can enhance bone formation by activating a particular signaling pathway, pointing to new treatment options for osteoporosis.
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  • - The study investigates how air pollution and genetic factors interact to influence the risk of developing psoriasis, using data from over 450,000 participants in the UK Biobank who were followed for nearly 14 years.
  • - Researchers calculated an air pollution score (APS) based on multiple pollutants and a polygenic risk score (PRS) for psoriasis to assess the combined effects of pollution and genetic susceptibility.
  • - Findings revealed that individuals with high genetic risk and high air pollution exposure had a significantly higher risk of developing psoriasis, indicating that genetic susceptibility plays a crucial role in how air pollutants affect psoriasis onset.
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Aim: To explore nurses' perceptions of evidence-based nursing courses for undergraduates through academic-practice partnerships.

Design: A deductive thematic analysis based on the practice-academic logic model.

Methods: Fifteen academic and clinical nurses were interviewed between November and December 2023, either online or through face-to-face meetings.

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Aim: To develop an evidence-based nursing practice course framework for undergraduate nursing students from a perspective of academic-practice partnerships.

Background: Academic-practice partnerships could play a crucial role in bridging theory-practice gap in evidence-based nursing education. However, there is a lack of evidence-based nursing practice course framework for undergraduate nursing students from a perspective of academic-practice partnerships.

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Testosterone derived from testicular Leydig cells (LCs) is important for male sheep, and the testis is susceptible to external temperature. The present study aimed to explore the alleviating effect of selenomethionine (Se-Met) on heat-induced injury in Hu sheep LCs. Isolated LCs were exposed to heat (41.

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  • The study explored how brining and ultrasound affect the quality of snakehead fish fillets, particularly focusing on texture and color.
  • Results indicated that ultrasound and brine significantly improved the fillets' tissue structure and water-holding capacity, with ultrasound reducing shear force more than traditional marination.
  • The findings suggest that the combination of ultrasound and brining enhances the fillets' thermal stability and offers valuable insights for improving fish processing in the aquatic industry.
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The integration of barrier materials with pharmacological therapy is a promising strategy to treat intrauterine adhesions (IUAs). However, most of these materials are surgically implanted in a fixed shape and incongruence with the natural mechanical properties of the uterus, causing poor adaptability and significant discomfort to the patients. Herein, an injectable, biodegradable, and mechanically adaptive hydrogel loaded with platelet-rich plasma (PRP) is created by L‑serine and allyl functionalized chitosan (ACS) to achieve efficient, comfortable, and minimally invasive treatment of IUAs.

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Food allergies severely impact the health-related quality of life (HRQoL) of patients and their caregivers (family or informal caregivers). Currently there is no comprehensive review to provide an overview and critical assessment of the instruments in the field. Six databases were searched from inception until 10 August 2023, and a combination of subject terms and free words was used to search the literature.

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Lung cancer is one of the leading causes of cancer-related deaths worldwide that presents a substantial peril to human health. Non-Small Cell Lung Cancer (NSCLC) is a main subtype of lung cancer with heightened metastasis and invasion ability. The predominant treatment approaches currently comprise surgical interventions, chemotherapy regimens, and radiotherapeutic procedures.

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Background: Academic-practice partnerships have the potential to solve many challenges in evidence-based nursing practice which is crucial for high-quality care.

Aims: To identify the existing knowledge on academic-practice partnerships in evidence-based nursing practice.

Methods: We conducted this review following the Joanna Briggs Institute scoping review methodology.

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Ammonia pollution is an important environmental stress factors in water eutrophication. The intrinsic effects of ammonia stress on liver toxicity and muscle quality of rainbow trout were still unclear. In this study, we focused on investigating difference in muscle metabolism caused by metabolism disorder of rainbow trout liver at exposure times of 0, 3, 6, 9 h at 30 mg/L concentrations.

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Sodium-glucose cotransporter 2 (SGLT2) plays a pivotal role in mediating glucose reabsorption within the renal filtrate, representing a well-known target in type 2 diabetes and heart failure. Recent emphasis has been directed toward designing SGLT2 inhibitors, with C-glycoside inhibitors emerging as front-runners. The architecture of SGLT2 has been successfully resolved using cryo-electron microscopy.

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  • * A new method using dissolving microneedles (MNs) coated with chitosan and filled with hollow mesoporous silica nanoparticles containing MTX (MTX@HMSN/CS) allows for better delivery directly to affected skin areas.
  • * This innovative approach shows improved therapeutic effects by maintaining drug concentration for longer periods and reducing inflammation, allowing for less frequent treatments without compromising effectiveness.
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Multiple time-series graphs are commonly used for data visualisation, but few scholars have investigated the impact of graphical attributes on decision-making efficiency. This study explores the effects of graphical attributes of varying redundancy conditions on decision-making efficiency. Two experimental conditions were developed for the experiment: non-redundant (independent graphical attributes: colour, linear and marker) and redundant (combinations of two and more graphical attributes: colour and linear, colour and marker, etc.

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To investigate the impact of environmental noise on the cognitive abilities of drivers, this study, using in-vehicle voice interaction as an example, conducted laboratory experiments to assess the effects of road traffic noise, entertainment noise, and white noise stimuli on drivers' attention and short-term memory. The noise levels simulated to mimic acoustic conditions during car driving ranged from 35 dB(A) to 65 dB(A). The conclusions drawn were as follows: (1) Noise levels directly influenced subjective annoyance levels, with annoyance linearly increasing as noise levels escalated; (2) Both attention and short-term memory task reaction times of drivers were significantly influenced by noise types.

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The migration of γδ T lymphocytes toward skin lesions and their concomitant pathogenic IL-17A production play a crucial role in the pathogenesis of psoriasis. However, the regulatory mechanisms of IL-17A production by γδ T cells and their migration remain to be fully explored. Intracellular GRP78 is a molecular chaperone that regulates endoplasmic reticulum stress, whereas secretory GRP78, as a member of the resolution-associated molecular patterns, exerts immunoregulatory effects.

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Background: Nursing interns often experience lots of challenges during their clinical nursing internships, which can adversely affect career decisions and result in a squandering of nursing education resources. Patient safety attitudes, professional identity and climate of caring may affect nursing interns' clinical experience. However, more evidence is requested to validate these relationships for nursing educators to develop effective education programs and facilitate interns' successful transition.

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Aqueous zinc-ion batteries are promising due to inherent safety, low cost, low toxicity, and high volumetric capacity. However, issues of dendrites and side reactions between zinc metal anode and the electrolyte need to be solved for extended storage and cycle life. Here, we proposed that an electrolyte additive with an intermediate chelation strength of zinc ion-strong enough to exclude water molecules from the zinc metal-electrolyte interface and not too strong to cause a significant energy barrier for zinc ion dissociation-can benefit the electrochemical stability by suppressing hydrogen evolution reaction, overpotential growth, and dendrite formation.

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Background: Alzheimer's disease (AD) is a neurodegenerative disorder and the predominant type of dementia worldwide. It is characterized by the progressive and irreversible decline of cognitive functions. In addition to the pathological beta-amyloid (Aβ) deposition, glial activation, and neuronal injury in the postmortem brains of AD patients, increasing evidence suggests that the often overlooked vascular dysfunction is an important early event in AD pathophysiology.

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As a strong economic and populous province in China, Jiangsu is home to four endemic diseases. Despite efforts in the past decade, the prevention and control of these four endemic diseases are not uniform because of the different etiological chains and influencing factors of these diseases. Among the evaluation methodologies for endemic disease control, only one method is currently available for each disease.

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Aim: To determine the association between the perception of a caring climate in hospitals and patient safety attitudes of nursing interns, and the multiple mediating effects of professional identity and transition shock on this relationship.

Background: Limited research has been conducted on the involvement of nursing interns in patient safety management and the direct relationship between the perception of a caring climate in hospitals and patient safety attitudes of nursing interns. Furthermore, it remains unclear whether professional identity and transition shock play significant roles as mediating factors in this relationship.

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Context Bone morphogenetic proteins (BMPs) play an important role in the uteri. Repulsive guidance molecule b (RGMb; a.k.

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As a dietary supplement or functional food additive, vitamin D (VD) deficiency may impact extra-skeletal functions associated with metabolic syndrome (MetS) risk factors. However, the precise effects and mechanisms of VD supplementation on dyslipidemia and insulin resistance in MetS subjects remain controversial. Here, we investigate potential therapeutic targets, pathways and mechanisms of VD against MetS through a comprehensive strategy including meta-analysis, network pharmacology analysis, molecular docking, dynamics simulations, and quantum chemical calculations.

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Objective: To provide a scoping review of the existing literature regarding academic-practice partnership in evidence-based nursing education, with the goal of gathering evidence to support the establishment of such partnerships.

Background: Academic-practice partnerships play a crucial role in overcoming separation of theory and practice in evidence-based nursing education and promoting the adoption of evidence-based nursing practice. However, there is a lack of scoping review of related literature.

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