Objectives: Artificial intelligence (AI) tools utilizing machine learning (ML) have gained increasing utility in medicine and academia as a means of enhancing efficiency. ASReview is one such AI program designed to streamline the systematic review process through the automated prioritization of relevant articles for screening. This study examined the screening efficiency of ASReview when conducting systematic reviews and the potential factors that could influence its efficiency.
View Article and Find Full Text PDFBackground: Human neuroimaging studies have revealed the association between brain structure and masticatory function. However, the majority of the studies adopted a cross-sectional design, which hardly reveals the change in masticatory function and brain structure between different timepoints, and the dynamical association between changes in masticatory function and changes in brain structure has not been elucidated.
Objective: With a longitudinal design, we assessed the association between changes in masticatory performance (MP) and regional brain volume.
Collective migration is important to embryonic development and cancer metastasis, but migratory and nonmigratory cell fate discrimination by differential activity of signal pathways remains elusive. In oogenesis, Jak/Stat signaling patterns the epithelial cell fates in early egg chambers but later renders motility to clustered border cells. How Jak/Stat signal spatiotemporally switches static epithelia to motile cells is largely unknown.
View Article and Find Full Text PDFLiquid repellant surfaces have been shown to play a vital role for eliminating thrombosis on medical devices, minimizing blood contamination on common surfaces as well as preventing non-specific adhesion. Herein, an all solution-based, easily scalable method for producing liquid repellant flexible films, fabricated through nanoparticle deposition and heat-induced thin film wrinkling that suppress blood adhesion, and clot formation is reported. Furthermore, superhydrophobic and hydrophilic surfaces are combined onto the same substrate using a facile streamlined process.
View Article and Find Full Text PDFHealthcare acquired infections are a major human health problem, and are becoming increasingly troublesome with the emergence of drug resistant bacteria. Engineered surfaces that reduce the adhesion, proliferation, and spread of bacteria have promise as a mean of preventing infections and reducing the use of antibiotics. To address this need, we created a flexible plastic wrap that combines a hierarchical wrinkled structure with chemical functionalization to reduce bacterial adhesion, biofilm formation, and the transfer of bacteria through an intermediate surface.
View Article and Find Full Text PDFCorrection for 'Solution-processed wrinkled electrodes enable the development of stretchable electrochemical biosensors' by Yuting Chan et al., Analyst, 2019, 144, 172-179.
View Article and Find Full Text PDFElectrodeposition is widely used to fabricate tunable nanostructured materials in applications ranging from biosensing to energy conversion. A model based on 3D island growth is widely accepted in the explanation of the initial stages of nucleation and growth in electrodeposition. However, there are regions in the electrodeposition parameter space where this model becomes inapplicable.
View Article and Find Full Text PDFWearable biosensors are critical for enabling real-time and continuous health monitoring and disease management. Conductors that retain their conductivity under strain are an essential building block of these systems. Strategies based on stretchable materials or structures have enabled the development of electrodes that can withstand impressive strains before loss of conductivity.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2018
Photoelectrochemical (PEC) biosensors, with optical biasing and electrochemical readout, are expected to enhance the limit-of-detection of electrochemical biosensors by lowering their background signals. However, when PEC transducers are functionalized with biorecognition layers, their current significantly decreases, which reduces their signal-to-noise ratio and dynamic range. Here, we develop and investigate a wrinkled conductive scaffold for loading photoactive quantum dots into an electrode.
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