Publications by authors named "Yutaro Udagawa"

Article Synopsis
  • * The key to this synthesis is a bioinspired Ugi reaction, which efficiently combines components like (+)-axisonitrile-3, acetone, and L-glutamic acid in a one-pot process, resulting in a 70% yield.
  • * Additionally, we synthesized related compounds (+)-boneratamide B and (-)-boneratamide C methyl esters using a similar strategy, and determined their stereochemistry through X-ray analysis. *
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Article Synopsis
  • * The key intermediate for this synthesis, (-)-10-epi-axisonitrile-3, was created through a two-step process involving stereoselective cyclopropanation followed by a ring-opening reaction with the azide anion.
  • * The final target exigurin was successfully constructed by applying a bioinspired Ugi reaction that combined (-)-10-epi-axisonitrile-3 with formaldehyde, sarcosine, and methanol, linking its terpene and amino acid components through an amide bond.
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