Publications by authors named "Yutaro Shiota"

Article Synopsis
  • The study examined predictive factors for asthma exacerbation in severe asthma patients enrolled in the Okayama Severe Asthma Research Program over a one-year period.
  • A total of 85 patients, mostly older adults, were analyzed, with many requiring advanced treatments according to GINA guidelines and over half treated with biologics.
  • Key findings indicated that past exacerbation, low asthma control test scores, low lung function measures, and high IL-10 levels were significant predictors of future asthma exacerbation events.
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We herein report a case of pulmonary hyalinizing granuloma (PHG), which is a rare pulmonary mass. A 69-year-old man with no symptoms presented to our hospital because of the appearance of an abnormal shadow on chest X-ray. Computed tomography revealed a right middle-lobe mass with spicula and infiltration into the upper lobe.

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Dental infection can be an important source for septic pulmonary embolism (SPE), but only a few cases of SPE accompanying dental infection have been reported. The aim of this study was to characterize the clinical features of SPE induced by dental infection. Patients who fulfilled the diagnostic criteria described in the text were recruited in a retrospective fashion.

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Mediastinal lymph node carcinoma of unknown primary site is rare and may have a better prognosis if extensive treatment is performed. Case, A 69-year-old-male presented with a persistent cough. Chest computed tomography (CT) demonstrated a large tumor 9.

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We studied clinical and radiographic features of interstitial lung disease (ILD) during trimethoprim/sulfamethoxazole (TMP/SMX) administration. Ten patients who had received prednisolone treatment for underlying diffuse pulmonary disease showed various ILDs after introduction of TMP/SMX. The radiographic features of the ILDs were not consistent with infectious disease or exacerbation of the underlying disease, and these diagnoses were excluded radiographically and on clinical grounds during the differential diagnosis of the ILDs.

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The prognosis of malignant pleural mesothelioma is poor, but selected patients might benefit from multimodality treatment. To establish the means that are available to predict the variable course of the disease in malignant pleural mesothelioma patients, we retrospectively investigated the correlation of clinico-pathological features of 54 patients with survival. Twenty-three patients received treatment, while 31 were referred to supportive care only.

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We describe the use of short-term epoprostenol in a 61-year-old man with primary pulmonary hypertension. The patient was on a ventilator because of respiratory distress. Continuous infusion of epoprostenol was started and it initially reduced the pulmonary artery pressure by 32%.

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We report a case of small bowel perforation secondary to metastasis from a lung squamous cell carcinoma that occurred in a 72-year-old man. He was admitted to the hospital because of remittant hemoptysis after undergoing a right upper lobectomy. Fiberoptic bronchoscopy revealed bleeding from the right upper lobe bronchial stump that was due to recurrence of the tumor.

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Article Synopsis
  • A 92-year-old man with a long history of asbestos exposure presented with breathing difficulties and was found to have bilateral pleural effusions that worsened despite heart failure treatment.
  • Imaging showed pleura calcification, and the fluid was lymphocyte-rich but unresponsive to tuberculosis treatment, leading to further investigation.
  • Thoracoscopy revealed asbestos plaques but no malignancy, leading to a diagnosis of benign asbestos pleural effusions, which improved with prednisolone treatment.
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A case of a 29-year-old woman with intralobar pulmonary sequestration infected with Mycobacterium intracellulare is presented. A chest CT scan revealed a density in the posterior segment of the left lower lobe, and an acid-fast bacillus sputum culture yielded Mycobacterium intracellulare. After 3 months of treatment with clarithromycin, streptomycin, rifampicin and ethambutol, the patient underwent partial resection of the left lower lobe.

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Background: Allergen-stimulated IL-5 production by CD4+ T cells is the key issue in atopic asthma. On the other hand, virus-specific CD8+ T cells produce IL-5 and might play an important role in the pathogenesis of nonatopic asthma.

Objectives: We sought to compare the IL-5-producing T-lymphocyte subsets in the peripheral blood of atopic and nonatopic asthmatic subjects, especially the contribution of IL-5-producing CD8(+) T cells in nonatopic asthma.

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Article Synopsis
  • Two patients with septic pulmonary embolism were linked to periodontitis, showing symptoms like toothache, fever, and chest pain.
  • Chest CT scans revealed nodular shadows typical for septic pulmonary embolism in both cases.
  • Treatment involved a combination of antibiotics and dental surgery, proving effective for both patients, highlighting the need to consider periodontitis in similar cases.
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