Publications by authors named "Yutaro Minoura"
Case Rep Gastroenterol
January 2024
Article Synopsis
- Drug-induced liver injury (DILI) from 5-aminosalicylic acid (5-ASA) is a rare but serious condition, as illustrated by a case of a 58-year-old woman with ulcerative colitis who experienced severe liver enzyme elevation after starting treatment.
- Diagnostic tests, including blood tests and a liver biopsy, indicated acute lobular hepatitis and raised concerns about autoimmune hepatitis, leading to the discontinuation of 5-ASA.
- The patient's liver function improved with treatment, stressing the need for careful monitoring of liver health in individuals undergoing 5-ASA therapy.
Asia Pac J Clin Oncol
October 2024
Article Synopsis
- The study investigates the impact of antithrombotic drugs (ATs) on fecal immunochemical test (FIT) results for colorectal cancer (CRC) screening, comparing results between AT users and nonusers.
- Findings indicate that patients on ATs had lower adenoma detection rates (ADRs) and polyp detection rates (PDRs), though the overall predictive value for detecting invasive CRC remained similar.
- Notably, the use of warfarin was identified as a potential positive predictive factor for invasive CRC detection among AT users, suggesting it might have some influence on FIT outcomes.
Article Synopsis
- - The study assessed the effectiveness of a standardized review strategy for intravenous antibiotics in hospitalized Japanese patients with uncomplicated diverticulitis (UD) after previously using a physician's choice strategy.
- - Results showed a significant reduction in the median duration of antibiotic use from 5 to 4 days with the review strategy, as well as increased completion rates of the 3-day antibiotic course (from 6.6% to 25.3%).
- - However, the length of hospital stays and total healthcare costs did not decrease, indicating that while the review strategy improved antibiotic management, it didn't lead to shorter hospitalizations or lower costs.
