Predictive value of Dmax and %ΔSUVmax of F-FDG PET/CT for the prognosis of patients with diffuse large B-cell lymphoma.

Purpose: To investigate the prognosis value of a combined model based on F-fluoro-deoxyglucose positron emission tomography-computed tomography (F-FDG PET-CT) baseline and interim parameters in patients with diffuse large B-cell lymphoma (DLBCL).

Methods: We retrospectively analyzed the PET metabolic parameters and clinical data of 154 DLBCL patients between December 2015 and October 2020. All of these patients underwent F-FDG PET/CT scan before treatment and after three or four courses of chemotherapy.

An exploratory study of unexplained concentration of F-PSMA-1007 in the bladder for prostate cancer PET/CT imaging.

F-PSMA-1007 PET/CT imaging is increasingly used for the diagnosis, staging, and efficacy assessment of patients with prostate cancer. Compared with other PSMA tracers, F-PSMA-1007 is mainly cleared by the liver and bile and has lower urinary clearance, thus allowing a better assessment of the lesions around the bladder. However, there were some patients who showed an obvious concentration of the F-PSMA-1007 in the bladder, which may affect the observation of peripheral lesions, but the mechanism of this change is unknown.

Performance of F-FAPI PET/CT in assessing glioblastoma before radiotherapy: a pilot study.

Background: We aimed to determine the performance of  F-FAPI PET/CT used for preprocedural assessment of glioblastoma before radiotherapy.

Methods: Twelve glioblastoma patients having undergone incomplete surgical resection or biopsy were examined with  F-FAPI PET/CT and MRI scanning before radiotherapy. All patients had confirmed tumor residues according to findings of histopathological and/or long-term clinical and radiological follow-ups.

Exceptional renal metastasis from adenoid cystic carcinoma of nasopharynx seen on F-FDG PET/CT.

A 48-year-old man with a history of adenoid cystic carcinoma (ACC) of the nasopharynx, eight years after radio-chemotherapy, fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) was performed for follow-up. A lobulated mass with moderate and heterogeneous F-FDG uptake in the right kidney was observed, which was pathologically proven as ACC metastasis.

Physiological tracer distribution and benign lesion incidental uptake of Al18F-NOTA-FAPI-04 on PET/CT imaging.

Objective: To systematically investigate the physiological distribution and benign lesion incidental uptake of Al18F-NOTA-FAPI-04 (18F-FAPI) in cancer patients to establish the normal uptake range in relevant organs and lesions.

Methods: Twenty patients who underwent 18F-FAPI PET/CT imaging were retrospectively assessed. Organ and benign lesion tracer uptake was quantified based on standardized uptake values (SUVmax and SUVmean).

Evaluation of F-PSMA-1007 PET/CT in prostate cancer patients with biochemical recurrence after radical prostatectomy.

Purpose: Prostate-specific membrane antigen (PSMA) ligands targeting has shown promising results in staging of prostate cancer (PCa). The aim of present study was to evaluate the value of F-PSMA-1007 PET/CT in PCa patients with biochemical recurrence.

Methods: 71 patients with PCa after radical prostatectomy (RP) were included in the present study.

FAPI-04 PET/CT Using [F]AlF Labeling Strategy: Automatic Synthesis, Quality Control, and Assessment in Patient.

Ga labeled FAPI is the current standard for FAPI-PET, but its batch activity is limited. [F]AlF-NOTA-FAPI-04 is a promising alternative combining the advantages of a chelator-based radiolabeling method with the unique properties of fluorine-18. The objective of this study was to develop a quick automatic method for synthesis of [F]AlF-NOTA-FAPI-04 using a AllinOne synthesis system, and perform PET imaging with [F]AlF-NOTA-FAPI-04 on patients.

Quick Automatic Synthesis of Solvent-Free 16α-[F] Fluoroestradiol: Comparison of Kryptofix 222 and Tetrabutylammonium Bicarbonate.

Estrogen receptor (ER) expression level of human breast cancer often reflects the stage of disease and is usually monitored by immunohistochemical staining . The preferable non-invasive and real-time diagnosis is more accessible by PET scan using 16α-[F]FES. The objective of this study was to develop a quick automatic method for synthesis of solvent-free 16α-[F]FES using a CFN-MPS-200 synthesis system and compare the catalytic efficiency of two phase transfer catalysts, Kryptofix 222/KCO (K222/KCO) and tetrabutylammonium hydrogen carbonate (TBA·HCO).

[The application of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography in inflammation and infectious disease].

2-［ F］-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ( F-FDG PET/CT) combining positron emission tomography with computed tomography is used to evaluate the body's glucose metabolic changes under different conditions. In addition to its established role in oncological imaging, F-FDG PET/CT has clinical utility in suspected inflammation and infection. The technique can identify the source of infection in a timely fashion ahead of morphological changes, map the extent and severity of inflammation, guide the site for tissue biopsy and assess therapy response.

Trichostatin A reverses epithelial-mesenchymal transition and attenuates invasion and migration in MCF-7 breast cancer cells.

Breast cancer remains one of the leading causes of mortality in women, and epithelial-mesenchymal transition (EMT) serves an indispensable role in the invasion and migration of breast cancer cells. As a representative of classical histone deacetylase inhibitors (HDACIs), trichostatin A (TSA) has been demonstrated to reverse EMT in certain types of non-tumor cells and tumor cells. In the present study, the invasive and migratory abilities of MCF-7 cells were examined following treatment with TSA.

Effects of Fever on F-FDG Distribution In Vivo: a Preliminary Study.

Purpose: Elevated body temperature might change glucose metabolism in human organs. The purpose of this study is to explore F-FDG distribution in febrile patients on the day of F-FDG PET/CT scanning and compare it with patients with a normal temperature.

Procedures: F-FDG PET/CT was performed on 69 febrile patients and 82 patients with a normal temperature.

A Rare Presentation of Melanoma as a Retroperitoneal Mass Seen on FDG PET.

A 55-year-old woman presented with intermittent fatigue and abdominal pain. Ultrasound and CT scan showed a large heterogeneous mass in the retroperitoneum, suggestive of malignancy. F-FDG PET/CT was performed for staging.

Isolated Nasal Metastasis From Renal Cell Carcinoma 9 Years After Nephrectomy Seen on FDG PET.

A 56-year-old man presented with intermittent epistaxis. Nasopharyngoscope revealed a hemorrhagic mass occupying the left nasal cavity. The patient had a history of renal clear cell carcinoma.

[Progress of quantitative measurement of bone using Tc-methylene diphosphonate in osteoporosis].

As the incidence of osteoporosis (OP) is increasing year by year, high morbidity and mortality caused by osteoporotic fractures have become major problems of health in China and over the world. Quantitative measurement of bone using Tc-methylene diphosphonate ( Tc-MDP) provides global or local information of skeletal metabolism or transformation. In this paper, we make a brief review on the quantitative measurement of bone using Tc-MDP and expect to provide guidance for clinical diagnosis and treatment.

Uterine Metastasis From Gastric Adenocarcinoma Masquerading as Physiologic Endometrial Uptake in FDG PET/CT.

A 44-year-old woman with newly diagnosed gastric adenocarcinoma by gastroscopy underwent F-FDG PET/CT to evaluate possible metastasis. The images demonstrated intense activity in the region of uterine corpus, as well as greater gastric curvature. Physiologic uptake of endometrium was initially suspected, given the rarity with which extragenital cancers metastasize to the uterus.