Publications by authors named "Yutaka Hatayama"

Background: The patients taking direct oral anticoagulants (DOACs) are at high risk for developing ischemic stroke and delayed bleeding in upper gastrointestinal endoscopic submucosal dissection (ESD). We aimed to identify the optimal DOAC based on both adverse events in upper gastrointestinal ESD.

Methods: A retrospective population-based cohort study was conducted using the Diagnosis Procedure Combination database in Japan.

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The gastrointestinal (GI) tract harbors trillions of microorganisms known to influence human health and disease, and next-generation sequencing (NGS) now enables the in-depth analysis of their diversity and functions. Although a significant amount of research has been conducted on the GI microbiome, comprehensive metagenomic datasets covering the entire tract are scarce due to cost and technical challenges. Despite the widespread use of fecal samples, integrated datasets encompassing the entire digestive process, beginning at the mouth and ending with feces, are lacking.

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Chronic infection of is considered the principal cause of gastric cancers, but evidence has accumulated regarding the impact of tobacco smoking and alcohol consumption on the development of gastric cancers. Several possible mechanisms, including the activation of nicotinic acetylcholine receptors, have been proposed for smoking-induced gastric carcinogenesis. On the other hand, local acetaldehyde exposure and ethanol-induced mucosal inflammation have been proposed as the mechanisms involved in the development of gastric cancers in heavy alcohol drinkers.

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Article Synopsis
  • Endoscopic hemostasis is crucial for treating gastrointestinal bleeding but traditionally involves high-risk training on real patients; a new simulator, "Medical Rising STAR-Ulcer type," offers a safer practice option.
  • A study with 50 gastroenterology residents showed significant improvements in success rates for clipping hemostasis after simulation training, with rates rising from 64% to 86%.
  • Trainees reported enhanced self-confidence and proficiency post-training, appreciating structured learning while also noting some limitations of the simulator and the importance of ongoing skill development.
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Article Synopsis
  • ERCP (Endoscopic Retrograde Cholangiopancreatography) and EST (Endoscopic Sphincterotomy) are critical but risky procedures, highlighting the need for safer training methods, particularly for inexperienced learners.
  • A new simulator model was created to help trainees practice these procedures using real endoscopic tools and aligned with skills assessed by the Bethesda ERCP Skill Assessment Tool (BESAT).
  • The simulator received positive feedback from 30 gastroenterology trainees, showing a significant increase in satisfaction after use, indicating its effectiveness in enhancing training experiences.
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Article Synopsis
  • The video showcases a new simulator designed specifically for practicing endoscopic hemostasis techniques.
  • It highlights the simulator's ability to mimic real-life scenarios for medical training.
  • The demonstration emphasizes the importance of this tool in improving the skills of healthcare professionals in managing bleeding during endoscopic procedures.
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