Publications by authors named "Yutaka Daimaru"

Oncocytic carcinoma of the breast is rare and its molecular profiles remain poorly understood. MicroRNAs (miRNAs/miRs) have been identified as contributors to carcinogenesis at the post-transcriptional level; thus, an aberrant expression of miRNAs has attracted attention as a potential biomarker of numerous diseases, including cancer. The present study reports the case of a 76-year-old woman diagnosed with oncocytic carcinoma of the breast.

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Article Synopsis
  • CA 15-3 is a tumor marker for breast cancer primarily used to monitor therapy in advanced cases, but its role in systemic sclerosis-associated lung disease (SSc-ILD) is unclear.* -
  • A case study involving a 63-year-old woman with recurrent breast cancer and SSc-ILD highlighted the importance of recognizing lung complications during cancer treatment, especially after she reported shortness of breath after chemotherapy.* -
  • The study emphasizes the need for a differential diagnosis of lung involvement in breast cancer patients, indicating that elevated CA 15-3 levels can be linked to conditions like SSc-ILD instead of just cancer progression.*
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Background: Sarcoidosis is a benign systemic granulomatous disorder of unknown etiology. Cell-mediated immunity disorder is often found in sarcoidosis patients, and an association between malignant tumors and sarcoidosis has been suggested. Sarcoidosis and malignant disease can occur simultaneously or sequentially, leading to misdiagnosis and mistreatment.

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Background: Spontaneous regression (SR) is a rare phenomenon in which a cancer disappears or remits without treatment. We report a case of breast cancer that showed spontaneous tumor regression in the surgical specimen after core needle biopsy.

Case Presentation: A 59-year-old woman came to our hospital complaining of a painful lump in the right breast.

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Article Synopsis
  • Distant metastases from breast cancer commonly appear in bones, lungs, and liver, but gastric metastasis is rare and often asymptomatic.
  • This case report discusses a 45-year-old woman who developed isolated gastric metastasis from lobular breast cancer, which was detected through CT scans despite her being asymptomatic at the time.
  • The patient was treated with targeted therapies after the gastric lesions were confirmed as metastatic, highlighting that solitary gastric metastasis, especially without symptoms, should be considered in breast cancer survivors when gastrointestinal abnormalities are found.
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Primary duodenal adenocarcinoma is a rare disease, and cases with nodal metastases have a poor prognosis. A 46-year-old man complaining of bloody stool visited our hospital. Endoscopy, CT, and PET-CT showed adenocarcinoma in the 2nd portion of the duodenum.

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We report on a case of an infected urachal remnant successfully treated via a single-incisional laparoscopic technique. An 18-year-old woman was diagnosed with an infected urachal remnant. The center of the umbilicus was pulled and inverted from the skin, and the cephalic side of the urachus was dissected from the umbilicus.

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Background: Although cavernous hemangioma is one of the most frequently encountered benign hepatic neoplasms, hepatic sclerosed hemangioma is very rare. We report a case of hepatic sclerosed hemangioma that was difficult to distinguish from an intrahepatic cholangiocarcinoma by imaging studies.

Case Presentation: A 76-year-old male patient with right hypochondralgia was referred to our hospital.

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A 72-year-old woman with a sigmoid colon cancer and a synchronous colorectal liver metastasis (CRLM), which involved the right hepatic vein (RHV) and the inferior vena cava (IVC), was referred to our hospital. The metastatic lesion was diagnosed as initially unresectable because of its invasion into the confluence of the RHV and IVC. After she had undergone laparoscopic sigmoidectomy for the original tumor, she consequently had 3 courses of modified 5-fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus cetuximab.

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Benign papillary mesothelioma of the peritoneum is an uncommon lesion that is usually discovered by chance during a surgical procedure. This lesion resembles metastatic carcinoma in gross appearance; therefore, intraoperative diagnosis can be difficult. This report presents a case of benign papillary mesothelioma concurrent with gastric cancer.

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A 73-year-old man was referred to our hospital with sigmoid colon cancer in July 2009. CT and MRI showed synchronous multiple liver metastasis. After a sigmoid colon resection in August, he received convergent chemotherapy in combination with 5-fluorouracil(5-FU)/Leucovorin(LV)(RPMI regimen)and bevacizumab for liver metastasis.

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We treated two patients (each aged over 90 years) with Helicobacter pylori-negative nonsteroidal anti-inflammatory drug (NSAID)-caused duodenal ulcers, and had the opportunity to determine gastric acidity by means of 24-h pH monitoring. Endoscopic and histological examination showed no remarkable atrophic change in the gastric mucosa. The gastric pH was low throughout the day and night, and the gastric pH > or = 3 holding time ratio during 24 h was 17.

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