Analysis of the Effect of Human Type I Collagen-Derived Peptide on Bone Regenerative Capacity and Comparison with Various Collagen Materials In Vivo.

: Autologous bone grafting is the first choice for reconstructive surgery in bone defects due to trauma or malignant tumors. However, there is an increasing demand for minimally invasive alternatives involving bone regeneration using artificial materials. Biomimetic materials that replicate the body's microscopic structure, such as Cellnest, are gaining attention.

"Core-Shell" Wave Function Modulation in Organic Narrowband Emitters.

Efficient red-green-blue primary luminescence with an extraordinarily narrow band and durability is crucial for advanced display applications. Recently, the emergence of multiple-resonance (MR) from short-range atomic interactions has been shown to induce extremely narrow spectral widths in pure organic emitters. However, achieving wide-range color tuning without compromising color purity remains a persistent challenge for MR emitters.

Characterization of the cellular heterogeneity and bone regenerative potential of cultured human periosteal cells.

Introduction: Cell-based bone regenerative therapy exhibits considerable potential in the treatment of bone defects caused by trauma, disease, and congenital anomalies. The periosteum, a fibrous membrane covering the outer surface of bone, plays a crucial role in bone formation and regeneration by sourcing osteoprogenitor cells. The remarkable osteogenic potential of periosteal cells (PCs) has led to the effective clinical implementation of PC-based regenerative therapies and tissue engineering.

Nickel(0)-Mediated Transformation of Tetrafluoroethylene and Vinylarenes into Fluorinated Cyclobutyl Compounds.

In the presence of Ni /PCy , styrene was found to participate in oxidative cyclization with tetrafluoroethylene, thus leading to the corresponding nickelacycle with a unique η -π-benzyl structure. In addition, the flexibility of the coordination mode in the η -benzyl moiety allowed the partially fluorinated nickelacycle to undergo unprecedented amine-induced α-fluorine elimination, thus leading to the construction of a fluorinated cyclobutyl skeleton.

Low-crosstalk operation of directly modulated DFB laser array TOSA for 112-Gbit/s application.

A directly modulated DFB laser (DML) array transmitter optical sub-assembly (TOSA) operating at 112 Gbit/s was fabricated for the first time. The DML array chip, which was integrated with a GND pad, and the DML array sub-assembly were designed to suppress the adjacent electrical crosstalk of the DML array TOSA. The 3-dB bandwidths of the fabricated TOSA exceeded 18 GHz.

Novel approach for chirp and output power compensation applied to a 40-Gbit/s EADFB laser integrated with a short SOA.

We propose a novel approach for simultaneously controlling the chirp and increasing the output power of an EADFB laser by monolithically integrating a short-cavity SOA. We achieved a 40-Gbit/s 5-km SMF transmission at a wavelength of 1.55 μm by using an EADFB SOA with a lower power consumption than a stand-alone EADFB laser.

InP-based compact transversal filter for monolithically integrated light source array.

We developed an InP-based 4x1 transversal filter (TF) with multi-mode interference couplers (MMIs) as a compact wavelength multiplexer (MUX) 1700 μm x 400 μm in size. Furthermore, we converted the MMI-based TF to a reflection type to obtain an ultra-compact MUX of only 900 μm x 50 μm. These MUXs are made with a simple fabrication process and show a satisfactory wavelength filtering operation as MUXs of monolithically integrated light source arrays, for example, for 100G bit Ethernet.

Ultracompact, 160-Gbit/s transmitter optical subassembly based on 40-Gbit/s × 4 monolithically integrated light source.

The first ultracompact transmitter optical subassembly for long-distance, beyond-100-Gbit/s data communication systems based on a monolithically integrated light source is developed. The light source consists of four InGaAlAs-based electroabsorption modulator integrated DFB lasers (EADFB lasers) and their optical multiplexer and these components are monolithically integrated on one chip, resulting in very small chip size of 2.4 × 3.