Background: Surgical site infection (SSI) is one of the most important complications of surgery for gastroenterological malignancies because it leads to a prolonged postoperative hospital stay and increased inpatient costs. Furthermore, SSI can delay the initiation of postoperative treatments, including adjuvant chemotherapy, negatively affecting patient prognosis. Identifying the risk factors for SSI is important to improving intra- and postoperative wound management for at-risk patients.
View Article and Find Full Text PDFCancer-related systemic inflammation influences postoperative outcomes in cancer patients. Although the relationship between inflammation-related markers and postoperative outcomes have been investigated in many studies, their clinical significance remains to be elucidated in rectal cancer patients. We focused on the lymphocyte count/C-reactive protein ratio (LCR) and its usefulness in predicting short- and long-term outcomes after rectal cancer surgery.
View Article and Find Full Text PDFThere is a great interest in direct conversion of methane to valuable chemicals. Recently, we reported that silica-supported liquid-metal indium catalysts (In/SiO) were effective for direct dehydrogenative conversion of methane to higher hydrocarbons. However, the catalytic mechanism of liquid-metal indium has not been clear.
View Article and Find Full Text PDFGiven the role of Ca3.2 isoform among T-type Ca channels (T-channels) in somatic and visceral nociceptive processing, we analyzed the contribution of Ca3.2 to butyrate-induced colonic pain and nociceptor hypersensitivity in mice, to evaluate whether Ca3.
View Article and Find Full Text PDFThe mechanism of C-H activation of methane by liquid indium, which is the first step of the dehydrogenative conversion of methane to higher hydrocarbons, was investigated using density functional theory calculations. In the first-principle molecular dynamics trajectory at the experimental temperature (1200 K), low-coordinated indium atoms continuously appear on the disordered liquid surface. The C-H cleavage is endothermic on clean surfaces, while the low-coordinated indium atoms reduce the endothermicity significantly.
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