Publications by authors named "Yuta Nakamatsu"

Cancer stem cells (CSCs) have been implicated as critical mediators in the progression, chemoresistance and metastatic capabilities of diverse malignancies, including osteosarcoma (OS). The authors have succeeded in generating CSC‑like cells (MG‑OKS) from the OS cell line MG‑63 by transducing defined factors. A significant increase in small proline‑rich protein 1A (SPRR1A) expression, a cross‑linked envelope protein in keratinocytes, was observed in MG‑OKS cells.

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Article Synopsis
  • Synovial sarcoma is a rare and challenging tumor that requires innovative treatment strategies.
  • A 46-year-old woman with a specific type of this tumor in her thigh opted for two courses of Boron Neutron Capture Therapy (BNCT) instead of surgery, leading to significant tumor reduction.
  • After BNCT, the tumor was completely removed, and the patient can now walk independently without any recurrence, suggesting that BNCT could be a promising adjuvant therapy for this condition, though more research is necessary to solidify its effectiveness.
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A 14-year-old girl experienced acute left buttock pain during a sprint. At the local hospital, she was diagnosed with an avulsion fracture of the left ischial tuberosity. She was kept for observation for about 10 months; however, the buttock pain persisted, and the bone fragments did not unite.

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