Publications by authors named "Yuta Mizushima"

Low-intensity endurance exercise with blood flow restriction (KAATSU) is under consideration for use in cardiac rehabilitation. However, the physiological responses to such exercise have not yet been fully characterized. In an initial effort in healthy males (n = 11, age: 26.

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Background and Objectives: Extracellular water is increased in patients with edema, such as those with chronic heart failure, and it is difficult to assess skeletal muscle mass with the skeletal muscle mass index when extracellular water is high. We investigated the relationship between phase angle and physical function, nutritional indices, and sarcopenia in patients with cardiovascular diseases, including chronic heart failure. Methods and Study Design: In 590 patients with cardiovascular diseases (372 men), handgrip strength, gait speed, and anterior mid-thigh muscle thickness by ultrasound were measured, and the skeletal muscle mass index, phase angle, and the extracellular water: total body water ratio were measured with a bioelectrical impedance analyzer, and presence of sarcopenia was evaluated.

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Article Synopsis
  • A study was conducted on patients who underwent cardiac surgery to evaluate the safety and effectiveness of low-intensity resistance training with blood flow restriction (KAATSU RT) on muscle strength and size.
  • 21 patients were divided into a control group and a KAATSU RT group, with the latter performing specific leg exercises twice a week for three months in addition to standard rehabilitation.
  • The results showed that KAATSU RT was safe and led to significant increases in muscle thickness, skeletal muscle mass, walking speed, and knee strength without any side effects.
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Article Synopsis
  • * The results indicated that both skeletal muscle mass index (SMI) and PhA were significantly correlated with factors like age, grip strength, and nutritional status (measured by CONUT score), showing strong connections especially in males.
  • * The study concluded that PhA could serve as a valuable indicator of sarcopenia, malnutrition, and cachexia in patients, with specific cut-off values identified for different conditions based on sex.
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Blood flow restriction (BFR) has the potential to augment muscle activation, which underlies strengthening and hypertrophic effects of exercise on skeletal muscle. We quantified the effects of BFR on muscle activation in the rectus femoris (RF), the vastus lateralis (VL), and the vastus medialis (VM) in concentric and eccentric contraction phases of low-intensity (10% and 20% of one repetition maximum) leg extension in seven cardiovascular patients who performed leg extension in four conditions: at 10% and 20% intensities with and without BFR. Each condition consisted of three sets of 30 trials with 30 s of rest between sets and 5 min of rest between conditions.

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We examined the relationship between Short Physical Performance Battery (SPPB) and clinical and laboratory factors and the effect of sarcopenia and sarcopenic obesity (SO) on clinical and laboratory factors for cardiovascular disease (CVD) inpatients. CVD male (n = 318) and female (n = 172) inpatients were recruited. A stepwise multiple-regression analysis was performed to predict total SPPB scores and assess clinical and laboratory factors (physical characteristics, functional and morphological assessments, etc.

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