Publications by authors named "Yuta Mine"
Article Synopsis
- Upstaging to pT3a after partial nephrectomy for cT1 renal cell carcinoma (RCC) is uncommon, occurring in 3.6% of cT1a and 19% of cT1b patients within a study of 389 cases from 2011-2022.
- The median tumor size for upstaged cases was 43 mm, and during a 59-month follow-up, there were six recurrence events, highlighting a significant risk for those with Fuhrman grade ≥3.
- Five-year survival rates were reported as 75.7% for metastasis-free survival, 96.2% for cancer-specific survival, and 88.1% overall, indicating
Article Synopsis
- The study aimed to assess the safety and effectiveness of neoadjuvant treatment with degarelix acetate and low-dose estramustine phosphate in men with high-/very high-risk prostate cancer before surgery.
- A total of 187 patients participated, with 140 undergoing surgery after receiving 6 months of the treatment, highlighting adverse events, surgical outcomes, and rates of biochemical recurrence.
- Results showed that patients with very high-risk status and those who reduced the dose of estramustine phosphate had lower rates of biochemical recurrence, indicating that maintaining dose compliance may impact survival outcomes in this group.
Article Synopsis
- The study aimed to evaluate the safety of preserving the urethra during radical cystectomy by using frozen section analysis (FSA) to check for recurrence of urothelial carcinoma.
- Researchers analyzed 77 male patients who underwent FSA; those with abnormal results had their urethra removed, while those with normal results had it preserved.
- The findings showed a 100% negative predictive value for FSA, and after an average follow-up of 38 months, no urethral recurrences were detected, highlighting the potential usefulness of FSA in guiding treatment decisions.
Introduction: In certain cases of rectal malignancy in which invasion is confined to the prostate and/or seminal vesicles, bladder-sparing surgery may be chosen instead of total pelvic exenteration. However, even if the bladder is preserved, postoperative urinary dysfunction and vesicourethral anastomotic leakage are concern.
Materials And Surgical Technique: We employ various techniques based on robot-assisted radical prostatectomy for reconstructing the urinary tract.
Article Synopsis
- Bladder diverticula in older adults usually result from bladder outlet obstruction and are commonly treated alongside prostate issues using bladder diverticulectomy.
- The reported study involved three patients who successfully underwent bladder diverticulectomy through a single cystotomy during robot-assisted laparoscopic radical prostatectomy, which minimizes complications and reduces surgery time.
- The technique utilized a transvesical approach via the bladder neck for diverticula that are easily visible, making it a practical option compared to other methods that might require more invasive surgery.
Article Synopsis
- The study aimed to evaluate how the shape of central tumours affects outcomes for patients undergoing robot-assisted partial nephrectomy (RAPN).
- A total of 186 patients were analyzed, categorizing tumour shapes into four types and assessing their impact on achieving the defined "trifecta," which indicates successful surgical outcomes.
- Results showed that tumours with complex-hump shapes had a significantly higher likelihood of failing the trifecta, highlighting the importance of preoperative morphology assessment in surgical planning.
Article Synopsis
- - A 40-year-old woman presented with vomiting and diarrhea, and imaging showed a cystic mass near her renal and iliac arteries, prompting a biopsy.
- - Histopathology revealed spindle-shaped cell growth and positive markers for a perivascular epithelioid cell tumor; however, the final diagnosis was primary retroperitoneal lymphangioleiomyomatosis (LAM).
- - Since the tumor was deemed unresectable and the patient had no poor prognostic lung lesions, she was monitored for 6 months, remaining asymptomatic with stable imaging results.
Article Synopsis
- The study aimed to determine if placing prophylactic drains after laparoscopic nephroureterectomy for upper tract urothelial cancer is necessary.
- It analyzed outcomes of 164 patients from 2011 to 2021, comparing those with (D+) and without (D-) drain placement.
- Results showed no significant difference in complications between groups, but the D- group had a notably shorter hospital stay, indicating drains may not be needed.
Article Synopsis
- After 4 years of hormone treatment, his PSA levels improved significantly, leading to a decision for salvage robot-assisted prostate surgery due to non-metastatic castration-resistant prostate cancer.
- Post-surgery, the patient's PSA dropped to undetectable levels, allowing him to stop hormone therapy, and he remained free of cancer recurrence for 3 years.
Article Synopsis
- The study compares robot-assisted (CRO-RAPN) and laparoscopic (CRO-LPN) techniques in partial nephrectomy for patients with localized renal masses from July 2012 to June 2020.! -
- Results showed that CRO-RAPN had significantly better outcomes, including shorter operation and warm ischemic times, less blood loss, and lower complication rates compared to CRO-LPN.! -
- Overall, CRO-RAPN also demonstrated a higher preservation rate of kidney function and a greater trifecta achievement rate, indicating its superiority in surgical performance and patient recovery.!
A retrocaval ureter (RCU) is a rare cause of congenital ureteral obstruction that often requires surgical repair. We report two cases of RCU in adults treated with robot-assisted laparoscopic surgery. In both cases, we performed robotic ureteroureterostomy with dissection of the entire length of the retrocaval portion of the right ureter without complications.
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- The study assessed the effects of continuing antithrombotic therapy during surgery on bleeding and complications in patients undergoing laparoscopic radical nephrectomy and nephroureterectomy.
- It was conducted as a retrospective observational analysis, comparing outcomes between patients who continued their antithrombotic medications and those who did not, focusing on bleeding complications and other surgical markers.
- The findings suggest that perioperative antithrombotic therapy does not significantly increase bleeding risk, indicating it is safe to continue during these surgical procedures.
Article Synopsis
- Cytoreductive nephrectomy is a surgical technique used with systemic therapy to treat metastatic renal cell carcinoma, but its effectiveness alongside immune checkpoint inhibitors is debated.
- A 57-year-old woman with advanced renal cell carcinoma and lung metastases achieved complete response in her lungs following immunotherapy and underwent partial nephrectomy for the primary tumor after five months of treatment.
- One year after surgery, she remained free of cancer recurrence, suggesting that cytoreductive surgery may be a viable option in managing metastatic renal cell carcinoma.
Article Synopsis
- A study aimed to compare the effectiveness of two diagnostic methods, 5-ALA-mediated photodynamic diagnosis (PDD) and narrow-band imaging (NBI), for detecting bladder cancer during transurethral resection of bladder tumors (TURBT).
- In the study, 114 patients were given 5-ALA and their bladders were inspected using white light (WL), PDD, and NBI, with results compared to pathology outcomes.
- The findings revealed that PDD had a higher sensitivity for detecting cancerous lesions than NBI (89.6% vs. 76.2%), suggesting that adding PDD to conventional methods can improve cancer detection rates significantly, especially for carcinoma in situ (CIS
Wild-type measles virus (wtMeV) adapted well to cotton rat lung (CRL) cells after serial passages. In order to evaluate the contributions of the individual genes of wtMeV for adaptation, whole genome sequences of the adapted and original viruses were determined and analyzed. The results showed that there were two mutations in the whole genome of the adapted virus.
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