Publications by authors named "Yuta Karibe"

Article Synopsis
  • A rare case was reported where a 71-year-old man with advanced prostate cancer showed simultaneous presence of a BRCA2 mutation and microsatellite instability-high (MSI-high) status.
  • Following various treatments including hormone therapy and docetaxel, the patient's cancer progressed, leading to the introduction of pembrolizumab.
  • Remarkably, after two months of pembrolizumab treatment, the patient experienced a significant reduction in prostate-specific antigen (PSA) levels and a complete response to his metastatic lesions, with no adverse effects noted.
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A 71-year-old man with a history of hoarseness and right upper extremity numbness was referred to our department for evaluation of an intrathoracic mass that was detected on chest radiography and a right kidney tumor observed on computed tomography (CT). Histopathological examination of percutaneous kidney biopsy and bronchoscopic lung biopsy specimens revealed renal clear cell carcinoma with multiple lung metastases. The patient showed a poor risk based on the International Metastatic renal cell carcinoma Database Consortium score, and nivolumab plus ipilimumab were initiated as first-line therapy.

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