Publications by authors named "Yusuke Yokokawa"

Article Synopsis
  • The study focuses on placenta previa complicated by placenta accrete spectrum (PAS), emphasizing the need for preoperative diagnosis to ensure proper management of this serious condition.
  • Researchers analyzed MRI images from 145 patients to identify 11 features related to PAS, finding eight features significantly correlated with the condition, particularly placental/uterine bulge and myometrial thinning.
  • A decision tree model, based on five key MRI features, was developed and demonstrated high sensitivity (90%) and specificity (95.5%) for predicting PAS in patients diagnosed with placenta previa.
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Although endometriosis is primarily benign, it has been identified as a risk factor for endometriosis-associated ovarian cancer (EAOC). Genetic alterations in ARID1A, PTEN, and PIK3CA have been reported in EAOC; however, an appropriate EAOC animal model has yet to be established. Therefore, the present study aimed to create an EAOC mouse model by transplanting uterine pieces from donor mice, in which Arid1a and/or Pten was conditionally knocked out (KO) in Pax8-expressing endometrial cells by the administration of doxycycline (DOX), onto the ovarian surface or peritoneum of recipient mice.

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Purpose: Wasabi is a traditional plant seasoning with an anti-septic function. Recent studies revealed several functions of Wasabi, such as anti-inflammation; however, the anti-tumor effect against endometrial carcinoma (EMC) cells has not been examined. In the present study, we investigated the anti-tumor effect of 6-(methylsulfinyl) hexyl isothiocyanate (6-MITC), a major chemical compound of Wasabi, against various EMC cell lines in vitro and in vivo.

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A 29-year-old woman was admitted to our hospital due to diagnosis of pregnancy at 5 weeks and a day. She underwent valve replacement with mechanical heart valve (MHV: SJM valve) for congenital mitral valve regurgitation, when 11 years old. Warfarin 4 mg was used for anticoagulation.

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