Publications by authors named "Yusuke Tokoro"
Article Synopsis
- The study created a new monoclonal antibody (57R2A) to detect the GPR56 protein in mouse hematopoietic stem cells (HSCs), which was previously unexamined due to lack of suitable tools.
- Flow cytometry analysis revealed that GPR56 is highly expressed in a population of cells marked by CD34, c-Kit, and Sca-1, indicating these cells are enriched with HSCs.
- Long-term repopulation assays showed that all functional HSCs expressed GPR56, suggesting it is a reliable positive marker for identifying HSCs in mouse bone marrow.
Objective: B cells lacking RP105 produce autoantibodies in patients with SLE. Expression of B-cell activating factor (BAFF) binding receptors (BBRs) and survival of RP105(-) B cells from SLE patients were examined.
Methods: Detection of difference of gene expression between RP105(-) and RP105(+) B cells was done by DNA microarrays.