Scanning electron microscopy analysis of synovial and adipose mesenchymal stem cells adhering to cartilage.

Introduction: Mesenchymal stem cells (MSCs) are increasingly used for intra-articular injections in the treatment of knee osteoarthritis. The aim of this study was to use scanning electron microscopy (SEM) to compare the morphological characteristics of synovial and adipose MSCs.

Methods: Synovium and adipose tissues were concurrently harvested from eight patients with knee osteoarthritis.

Two cases of atypical femoral fracture in cancer patients administered with bone-modifying agents.

We report two cases of atypical femoral fracture (AFF) in patients with cancer. Two patients, a 53-year-old woman with breast cancer and a 77-year-old man with prostate cancer, could not walk after being injured in a fall. They used bone-modifying agents (BMA) for the prevention of bone metastasis for three and four years, respectively.