Late effects of osteosarcoma and its treatment in pediatric patients: A single-center experience.

Purpose: The success of osteosarcoma treatment strategies improved survival rates. The need of diagnosing and managing adverse effects is increasing. We aimed to investigate the outcomes and late results of pediatric osteosarcoma treatment in the survivors.

Patellar bone stock after extra-articular knee resection preserving extensor mechanism: A cadaveric study.

Objective: This study aimed to evaluate the thickness of the remaining patellar bone stock following extra-articular knee resection (EKR) preserving the extensor mechanism in human cadaveric knee joints.

Methods: A total of 14 human cadaveric knee joints (8 men and 2 women) were dissected, and the patellar thickness from the joint capsule insertion to the anterior cortex of the patella was measured using an electronic caliper. The mean age of the cadavers was 37 years (range=28-50).

The relationship between serum osteopontin and FGF 23 levels with valvular calcification in hemodialysis patients .

Backgrounds And Aims: Cardiovascular calcification is an important cause of morbidity and mortality in hemodialysis (HD) patients. Vascular and valvular calcification are indicators of increased tissue calcification. The relationship of osteopontin (OPN) - which is known as a vascular calcification inhibitor - and fibroblast growth factor-23 (FGF-23) - which its related to vascular calcification, as recently shown - to valvular calcification is unknown.

Parosteal lipoma as a rare cause of peripheral neuropathy and local irritation: A report of 12 cases.

Objective: The aim of this study was to evaluate the clinical features and functional results of patients with parosteal lipomas.

Methods: A total of 12 patients (8 females and 4 males; mean age: 45 (10-62) years) with parosteal lipomas who were treated between April 1986 and April 2014, were included into the study. The medical records of the patients were reviewed to analyze the clinical features and functional results of the patients.

Malignant triton tumor of the gluteal region in a patient unaffected by neurofibromatosis: A case report.

Malignant triton tumor (MTT) is a rare variant of malignant peripheral nerve sheath tumor (MPNST) made up of both malignant schwannoma cells and malignant rhabdomyoblasts. A 26-years-old male patient was admitted with an asymptomatic gluteal mass. Magnetic resonance imaging showed heterogeneous soft tissue mass and he underwent open biopsy.

Chemotherapy in primary osteogenic sarcoma in patients over the age of forty.

Objective: In this study, we sought to review the clinical and histopathological features and the chemotherapy regimens in osteogenic sarcoma in patients over 40 years of age, and we aimed at identifying the possible prognostic factors in this particular group of patients.

Methods: We reviewed 287 patients with osteosarcoma treated between the year 1986 and 2010. Patients from this group who met the following criteria were considered eligible for our study; presence of primary OS, had typical histological and radiographic features of OS, no prior history of cancer or any treatment elsewhere and no prior history of preexisting bone abnormalities.

Primary malignant fibrous histiocytoma of long bones: long-term follow-up.

Objectives: This study aims to evaluate patients diagnosed with malignant fibrous histiocytoma and investigate the possible prognostic factors associated with duration of survival.

Patients And Methods: The study, which was conducted between May 1994 and September 2013, included 14 patients diagnosed as malignant fibrous histiocytoma (12 males, 2 females; median age 48 years; range 17 to 64 years). We evaluated patients' demographic features, location of the pathology, histological findings, surgical margins, and treatment modalities and investigated the effects of these parameters on survival.

Can Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography Be Used As a Useful Method to Evaluate the Treatment Response to Neoadjuvant Therapy Combined With Sorafenib and Anti-VEGF in Children Diagnosed With Metastatical Bone Sarcoma?

Background: The prognosis is still poor for patients with a metastatic bone tumor and new treatment approaches (anti-VEGF and tyrosine kinase inhibitors vs) are therefore needed.

Objectives: The aim of our study was to evaluate how the primary and metastatic lesions of our patients with a bone tumor were affected by these treatments and to determine the importance of the 18F-FDG PET method.

Patients And Methods: Twenty metastatic bone tumor cases were included.

Management of tumors and tumor-like lesions of the hand: a review of 191 patients.

Objectives: In this study, we aimed to investigate the incidence of benign and malignant hand tumors, localization and management approaches.

Patients And Methods: Between March 1986 and October 2008, 191 consecutive patients (86 males, 105 females; mean age 35.06 years; range 1 to 96 years) who were diagnosed with tumors or tumor-like lesions of the hand in our clinic were retrospectively analyzed.

Surgical management of grade I chondrosarcoma of the long bones.

The aim of this study was to compare the rates of local recurrence according to surgical treatment options in low-grade chondrosarcomas of the long bones. A retrospective review was made of 30 consecutive patients (12 male, 18 female) with a mean age of 40.7 years (range: 16-69 years) with intramedullary low-grade chondrosarcoma of the long bones treated either by intralesional curettage or wide resection at our institution between 1995 and 2011.

Bone tumors of the clavicle: risk of malignancy in the elderly and safe needle biopsy.

The clavicle is a rare site for bone tumors and little is known from the limited literature about the prognostic factors and management techniques, including biopsy. The method of biopsy is controversial in the clavicle because of the risk of injury to the neighboring neurovascular structures. Twenty patients with clavicular lesions were retrospectively reviewed with clinical, radiological, and histopathological reports.

Bilateral triple renal arteries.

Knowledge of the variations of the renal artery has grown in importance with increasing numbers of renal transplants, vascular reconstructions and various surgical and radiologic techniques being performed in recent years. We report the presence of bilateral triple renal arteries, discovered on routine dissection of a male cadaver. On the right side, one additional renal artery originated from the abdominal aorta (distributed to superior pole of the kidney) and one other originated from the right common iliac artery (distributed to lower pole of the kidney).

[Chondroblastoma of the metatarsal bone and its 17-year follow-up].

Chondroblastoma is a rare bone tumor of cartilaginous origin. Metatarsal involvement is very rare, with a few cases. We presented a case of chondroblastoma localized in the fourth metatarsal bone.

Benign fibrous histiocytoma of the hand: a case report and literature review.

Benign fibrous histiocytoma (BFH) of the bone is a rare benign lesion characterised by the presence of fibroblasts and histiocytes. Fibrohistocytic lesions involving bone with identical histological appearances are common during childhood such as fibrous cortical defect. However, BFH is very rare and can only be differentially diagnosed with its presentation, localisation and radiologic features.

Tumours and tumour-like lesions of the patella: a report of eight cases.

We report eight cases of tumours and tumour-like lesions of the patella. Six lesions were primary and two were metastatic, both originating from adenocarcinoma of the rectum. Patients with anterior knee pain related with a tumourous condition usually have significant delay in diagnosis.

Primary leiomyosarcoma of bone: a report on three patients.

Primary leiomyosarcoma of bone is a rare aggressive tumor that occurs mainly in older people. It resembles other malignancies clinically and radiologically, and differential diagnosis is based on histopathology, including immunohistochemistry. If leiomyosarcoma is found in bone, the possibility that it is a metastasis from a distant tumor should be investigated.

The use of fibular autograft and ankle arthrodesis for aggressive giant cell tumor in the distal tibia: a case report.

The case describes successful distal tibial resection, fibular autograft, and ankle arthrodesis in two patients who had giant cell tumor in the distal tibia. At long-term followup, the patients had no pain and no limitation in daily or low-impact recreational activities. In conclusion, due to the large resection that is often necessary for aggressive tumors, fibular autograft and ankle arthrodesis may be a useful method in the distal tibia.

Primary angiosarcoma of the fibula : a case report.

Primary vascular neoplasms of bone are rare and have a poor prognosis. Angiosarcoma of bone originates in vascular endothelial cells within bone tissue. Patients may present with unifocal or multifocal osseous disease.

Surgical treatment of osteoblastoma : a report of 20 cases.

Osteoblastoma is a locally aggressive osteoblastic lesion of bone with rare malignant transformation. We retrospectively evaluated 20 patients who were diagnosed and surgically treated for osteoblastoma in our institution. Their mean age was 22.

Aneurysmal bone cyst recurrence in children: a review of 56 patients.

Background: Aneurysmal bone cysts (ABCs) are benign lesions that are usually treated with intralesional procedures. The clinical behavior of ABCs is reported to be more aggressive in younger patients, with high recurrence rates after surgical treatment by several authors. The purpose of this study was to review longitudinally the demographic data and outcome of current surgical techniques in children with ABC treated at a single institution and to determine the possible risk factors for recurrence, which may be detected at initial examination, including age, presenting complaint, and radiological characteristics.

[Alveolar soft part sarcoma of the extremities: an evaluation of four cases].

We presented four patients (3 women, 1 man; mean age 40 years; range 20 to 56 years) who had alveolar soft part sarcoma in the left arm, right elbow, right tibia, and left thigh, respectively. All the patients presented with a mass. Two patients had lung metastasis at the time of diagnosis.

[Prognostic factors in patients with malignant fibrous histiocytoma of the extremities].

Objectives: We evaluated prognostic factors in patients with malignant fibrous histiocytoma of the extremity.

Methods: The study included 26 patients (22 males, 4 females; 15 patients < age 60) with a diagnosis of malignant fibrous histiocytoma of the extremity. Clinical and pathological data were analyzed including age, gender, affected extremity, presentation status (primary or recurrent), localization (proximal or distal), size, depth, and grade of the tumor, resection quality, adjuvant therapy, and the presence of distant metastasis at the time of diagnosis.