Hematological changes, oxidative stress assessment, and dysregulation of aquaporin-3 channel, prolactin, and oxytocin receptors in kidneys of lactating Wistar rats treated with monosodium glutamate.

High consumption of locally produced delicacies could expose nursing mothers to high monosodium glutamate (MSG) levels, frequently used as a necessary condiment in low-income countries. Thus, this study evaluated some novel preliminary changes in renal hormonal receptors, the aquaporin-3 channel, oxidative stress markers, and hematological indices induced by monosodium glutamate in lactating rats. Post-parturition, twenty-four (24) lactating Wistar rats were divided into four (4) groups of six rats each (n = 6).

mitigates microvascular complications of type 2 diabetes mellitus: the involvement of oxidative stress and aldose reductase.

Objectives: () tubers are used in the management of diabetes. This research evaluated the effect of ethylacetate extract of (EACA) on microvascular complications and the possible association of oxidative stress and aldose reductase in type 2 diabetic rats.

Methods: tubers were subjected to sequential extraction until ethylacetate extract was obtained using a soxhlet apparatus.

mitigates microvascular complications of type 2 diabetes mellitus: the involvement of oxidative stress and aldose reductase.

Objectives: () tubers are used in the management of diabetes. This research evaluated the effect of ethylacetate extract of (EACA) on microvascular complications and the possible association of oxidative stress and aldose reductase in type 2 diabetic rats.

Methods: tubers were subjected to sequential extraction until ethylacetate extract was obtained using a soxhlet apparatus.

Antihyperglycaemic activity of ethylacetate extract of Chlorophytum alismifolium in type 2 diabetes: The involvement of peroxisome proliferator-activated receptor-γ and dipeptidyl peptidase-4.

Objective: This research is to investigate the antihyperglycaemic activity and the underlying mechanisms of action of the ethylacetate extract of Chlorophytum alismifolium (EACA) tubers in a type 2 diabetes model.

Methods: The tubers were processed and sequentially extracted in hexane followed by ethylacetate, using a Soxhlet apparatus, and subjected to gas chromatography-mass spectrometry (GC-MS). The acute toxicity of EACA was investigated in albino Wistar rats.

Effects of Mosquito coil Smoke Inhalation on Spatial Memory in Mice.

Background: Mosquito coil (MC) is widely used to repel mosquitoes in order to prevent malaria in many malaria-endemic countries. Although we are fully aware and concerned about carbon monoxide (CO) and its toxicity, exposure to CO from common, though occult sources like MC smoke is often overlooked. Equally, the adverse health effects, especially to the brain, are usually underestimated.

The use of glycated haemoglobin (HbA1) in determining glycemic control (and relevance of BMI) in diabetic patients in Ahmadu Bello University Teaching Hospital Zaria, Nigeria.

This study was carried out to specifically investigate the local HbA1 level and determine extent of (if any) variation from the WHO (World Health Organization) recommended threshold for the diagnosis of diabetes and prediabetes using blood glucose as a benchmark. In addition, we also looked to see what role BMI (Body Mass Index) plays among subjects used for the study. 152 subjects were used for the study: 101 diabetic subjects and 51 non-diabetic control subjects.