Publications by authors named "Yusuf Orhan"

The aim of this study was to evaluate whether insulin sensitivity, inflammatory response, and plasma lipid profile are associated with circulating adiponectin levels in nondiabetic healthy women. The authors also assessed whether adiponectin has any effect on high-density lipoprotein cholesterol-linked paraoxonase 1 (PON-1) activity and on the susceptibility of low-density lipoproteins to oxidation. Plasma adiponectin was measured in 91 nondiabetic premenopausal women, and the patients were then divided into quartiles.

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Article Synopsis
  • The study investigates the link between educational status and obesity as well as cardiovascular risk factors among overweight and obese women in Turkey.
  • A total of 3,080 women were analyzed, revealing that those with lower education levels had significantly higher risks for obesity-related issues and cardiovascular problems.
  • The findings suggest that improving educational opportunities could help mitigate obesity and its associated health risks in this population.
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Objective: Patients with hyperthyroidism occasionally need rapid restoration to the euthyroid state. In view of the increased enterohepatic circulation of thyroxine (T4) and triiodothyronine (T3) in thyrotoxicosis, and metabolic effects of konjac glucomannan in gastrointestinal system, we aimed to determine the activity of glucomannan in treatment of hyperthyroidism.

Methods: A prospective, randomized, placebo-controlled, one-blind study design was used with newly diagnosed 48 hyperthyroid patients (30 patients with Graves' disease and 12 with multinodulary goitre).

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Objective: To determine 'alarm and action levels' of waist circumference (WC) in overweight and obese Turkish women and investigate the relationship with cardiovascular risk factors.Research subjects and methods: Four thousand three hundred and seventy-five women aged 18-81 years selected from Istanbul Faculty of Medicine Obesity outpatient clinic. WC, waist-to-hip ratio (WHR), body mass index [(BMI) (weight (kg)/height (m(2)))], blood pressure, and biochemical parameters were analyzed.

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Article Synopsis
  • A 19-year-old female patient with a history of kidney stones and urinary tract infections was found to have low magnesium levels and high calcium levels, despite treatment with thiazide diuretics.
  • Genetic testing revealed a specific mutation (G227R) in the CLDN16 gene, linked to her hypomagnesemia and hypercalciuria.
  • This case highlights the hereditary nature of her condition, suggesting that even family members with a single copy of the mutation may be at risk for kidney stones.
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The aim of this study is to determine the body fat distribution and cardiovascular disease risk factors in pre- and postmenopausal obese women matched for weight, height and body mass index (BMI). Study group consisted of 405 premenopausal overweight/obese (BMI > 27 kg/m2, mean 37.83 +/- 6.

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