Publications by authors named "Yusuf Mustapha"

Background: Pregnancy-Related Acute Kidney Injury (PRAKI) is an important contributor to maternal-fetal morbidity and mortality. The burden of PRAKI in sub-Saharan Africa is not well documented. We conducted a systematic literature review and meta-analysis to estimate the prevalence of PRAKI in sub-Saharan Africa.

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Introduction: foodborne diseases are an emerging public health challenge due to the global increase in vended food. This study aimed to compare food safety knowledge among mobile and canteen food handlers in Kano metropolis.

Methods: a comparative cross-sectional design was used to study 310 mobile food vendors and 310 canteen food handlers selected using a multi-stage sampling technique.

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Article Synopsis
  • - The study investigated how administering vasoactive intestinal polypeptide (VIP) affects inflammation and the expression of intestinal tight junction mRNA in lambs on grain-based diets, comparing two groups: one given VIP and another given saline (control).
  • - Although there were no significant differences in tight junction mRNA expressions across intestinal regions, VIP-treated lambs showed increased levels of anti-inflammatory cytokines and lower lipopolysaccharide (LPS) concentrations, indicating reduced inflammation.
  • - Overall, while VIP did not appear to change tight junction mRNA levels, the treatment seemed to lower inflammation by decreasing LPS levels in lambs fed grain diets.
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Objectives: Drug resistance in tuberculosis (TB) is a very important public health threat that should not be ignored. Understanding the gender, age, and characteristics of individuals affected by TB (without HIV, diabetes, or hepatitis B complications), particularly in terms of drug resistance or susceptibility, is crucial for effective prevention and management strategies, as most studies focus on TB/HIV co-infection.

Methods: A cross-sectional case study of age and gender was carried out in 140 individuals grouped into drug-resistant tuberculosis (DR-TB), drug-susceptible tuberculosis (DS-TB), and apparently healthy controls (AHCs).

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Maggots in a wound ("myiasis") cannot be considered maggot therapy (therapeutic myiasis) unless, at a minimum, the species is known to be safe and effective, and the maggots have been properly disinfected. Documenting treatment details is critical and allows us to determine the cause of problems, if they arise.

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Background: The burden of food-borne diseases is becoming a global problem. The aim of this study was to assess and compare personal hygiene knowledge among street food vendors and canteen food handlers in the Kano metropolis.

Methodology: An explanatory sequential mixed methods study was carried out using a structured interviewer-administered questionnaire, focus group discussion guide and observation checklist, to assess and compare personal hygiene knowledge among street food vendors and canteen food handlers in Kano metropolis, Nigeria.

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Article Synopsis
  • - The study investigated the effects of vasoactive intestinal polypeptide (VIP) on growth and digestion in lambs, using 16 wether lambs split into two groups: one receiving saline and the other receiving VIP injections for 28 days.
  • - Results showed lambs treated with VIP had improved growth metrics, meaning they gained more weight and had better feed efficiency, but there were no significant differences in nutrient intake or digestion between the two groups.
  • - Additionally, while VIP treatment increased the size of the cecum and decreased brain weight, it did not affect digestive enzyme activity significantly, indicating that VIP may enhance growth specifically in lambs on grain diets without altering overall digestion.
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Objective: A case description of a rare occurrence of female genital schistosomiasis affecting the upper genital tract that presented with features mimicking an ovarian neoplasm.

Case Report: Female genital schistosomiasis is a neglected clinical manifestation of the water-born parasitic disease which occurs due to the presence of schistosome eggs in the genitalia of women. A 23-year-old nulliparous woman presented with progressive abdominal distension.

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Introduction: rubella is a leading cause of vaccine preventable birth defects especially in developing countries. Acquisition of infection with the rubella virus in early pregnancy exposes the fetus to a very high chance of developing congenital rubella syndrome. The neonate is born with multiple abnormalities with the triad of congenital cataract, deafness and cardiovascular abnormalities like ventricular septal defect or patent ductus arteriosus.

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Objective: The report of the outbreak of body louse in northwestern Iran after three decades reminds us again of the danger of the re-emerging of previous epidemics.

Results: The results of the study that nearly 70% of the patients in a rehabilitation Centre were infected with body louse. In this study, scientific measures were taken to prevent the spread of body lice to healthy people, including isolation of the patients, washing the clothes of those infected at high temperatures, and spraying the rest area, beddings, and blankets.

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Objective: Approximately 13% of people living with diabetes develop one or more ulcers during the course of the disease, and diabetic foot ulcer (DFU) is responsible for >60% of lower limb amputations worldwide. This case series aimed to demonstrate the effectiveness of medical-grade maggots on DFUs in promoting wound healing and reducing related hospital stays in northern Nigeria.

Method: Maggot debridement therapy (MDT) was applied to the DFUs of patients who consented to this treatment between January-August 2021 at the Orthopaedic Unit of the Aminu Kano Teaching Hospital (AKTH), Kano, Nigeria.

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The use of Attractive Toxic Baits (ATBs) is considered to be a low-risk practical method for controlling cockroaches. This study evaluates the attractiveness of a lab-made, fipronil-containing bait, and its effect on the food consumption and mortality of the German cockroach Blattella germanica, under field and laboratory conditions. Different developmental stages of the cockroach were used to determine their preferred carbohydrate/protein rich foods and examine the effectiveness of lab-made baits.

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The relationship between weather variables and dry matter intake (DMI) in beef steers was examined using daily intake data from 790 beef steers collected through a computer-controlled feeding system in nonsummer months. Daily data were condensed into weekly averages (N = 13,895 steer-weeks). The variables considered to predict DMI (2.

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Objective: Maggot debridement therapy (MDT) is an emerging procedure involving the application of sterile maggots of the Dipteran species (commonly ) to effect debridement, disinfection and promote healing in wounds not responding to antimicrobial therapy. Data on MDT in sub-Saharan Africa (including Nigeria) are scarce. This study aimed to use medicinal grade maggots as a complementary method to debride hard-to-heal necrotic ulcers and thereby promote wound healing.

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Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate-Cyclase-Activating Peptide (PACAP) are anti-inflammatory neuropeptides that play important roles in human and rodent gut microbiota homeostasis and host immunity. Pharmacologically regulating these neuropeptides is expected to have significant health and feed efficiency benefits for agriculturally relevant animals. However, their expression profile in ruminant tissues is not well characterized.

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There is increased possibility that combined herbal constituents may interact to increase toxicity and lower efficacy. Ruzu herbal bitters (RHB) is a blend of extracts from Curculigo pilosa, Uvaria chamae, and Citrullus colocynthis, each of which has been shown to possess important bio-effects. There is anecdotal evidence for efficacy of RHB in neurological disorders; however, there are no data on possible neurotoxic effects of RHB.

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Background: Malaria is a major public health problem in Nigeria with 97% of its population with high morbidity and mortality. Mosquitoes play an important role in the transmission of malaria parasites. This study was conducted to evaluate the current resistance status of to insecticides.

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Background: Malaria is a parasitic vector-borne disease endemic in the tropical and subtropical countries of the world. The aim of this study was to investigate the current activities of the detoxification enzymes in resistant and susceptible s.l.

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Article Synopsis
  • Understanding the prevalence of dirofilariasis in mosquitoes is essential for developing effective vector control programs, especially beyond just treating infected dogs.
  • A systematic review was conducted on studies up to 2019, revealing an overall prevalence of infected mosquitoes ranging from 1.5% to 48.5%, with specific prevalence rates identified in different regions, particularly the Eastern Mediterranean.
  • The analysis found that certain mosquito species, particularly within specific genera, are identified as the main vectors for dirofilariasis, emphasizing the need for targeted control efforts.
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Although sexual health is affected by Parkinson's disease (PD), the effect on testicular health and/or sperm quality is not well discussed. After 21 days of rotenone lesioning, we observed dopaminergic neuronal degeneration in the substantia nigra and hypothalamus. There were minimal SPACA-1-expressing epididymal spermatozoa with morphological abnormalities, scanty luminal spermatozoa and reduced testicular spermatids and post-meiotic germ cells indicating hypospermatogenesis.

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Article Synopsis
  • Hierarchical ZnO/ZSM-5 catalysts were synthesized through desilication and the addition of 2 wt % ZnO, maintaining the zeolite structure despite some loss in crystallinity and acidity.
  • The catalysts demonstrated impressive performance over 5 hours, with the selectivity for aromatics (benzene, toluene, xylenes) showing a trend favoring higher NaOH concentrations, while propane conversion rates decreased as NaOH concentration increased.
  • Compared to a reference catalyst, the hierarchical ZnO/ZSM-5 catalysts achieved better aromatic selectivity (up to 61.0%) and significantly lower production of heavier aromatics (C9+) during the reaction.
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Molecular analysis of antifolate resistance-associated genes-dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps) of Plasmodium vivax is important in predicting the emergence of drug resistance to sulphadoxine-pyrimethamine (SP). The present study aimed to determine the polymorphism of dhfr and dhps genes in P. vivax field isolates.

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as free-living parasites are scattered ubiquitously, throughout the world. This study was aimed to evaluate the presence of spp. genotypes in the recreational water sources in Gorgan County, the capital of Golestan Province using both morphological and molecular approaches.

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This study assesses the succession of insects on rabbit carcass. The study was conducted in sunny and shaded sites in the west of Iran during four seasons in 2016 and 2017. Based on the results of this study, various factors such as body size, carcass location, and carcass injury could affect the pattern of insect succession on carcass.

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