Background: Anthropometric measurements used to predict cardiovascular disease vary worldwide but are mostly derived from those of Caucasian ancestry. We sought to undertake such measurements in the little studied Bangladeshi population.
Methods: The MAGPIE (Multidimensional Approach of Genotype and Phenotype in Stroke Etiology) study is a Bangladeshi stroke case-control study that recruited nationwide between January 2022 and June 2024.
Background And Aims: Stroke is a leading cause of mortality and morbidity in Bangladesh. It is estimated that genetic determinants account for around 40%-60% of its etiology, similar to environmental factors. This study aimed to provide a better understanding of the genetic, environmental, and clinical risk factors in stroke patients from Bangladesh.
View Article and Find Full Text PDFWhile groundwater is commonly perceived as safe, the excessive presence of trace metals, particularly arsenic (As), can pose significant health hazards. This review examines the current scenario of pollutants and their mitigations focusing on As contamination in groundwater across multiple nations, with a specific emphasis on the Indian Peninsula. Arsenic pollution surpasses the WHO limit of 10 ppb in 107 countries, impacting around 230 million people worldwide, with a substantial portion in Asia, including 20 states and four union territories in India.
View Article and Find Full Text PDFIn the current investigation, the combination of selenium (Se) and epibrassinolide (EBL) exhibited a promising alleviative response against the concurrent stress of heat and drought in wheat plants. The compromised growth and photosynthetic performance of wheat plants under the combined stress of heat and drought were substantially improved with the treatment involving Se and EBL. This improvement was facilitated through the expression of Q9FIE3 and O04939 proteins, along with enhanced antioxidant activities.
View Article and Find Full Text PDFBackground: Research on breast cancer risk factors and mortality is gaining recognition and attention globally; there is need to add more information on its determinants among patients admitted in hospital. Some studies on risk factors and mortality of breast cancer in Nigeria hospitals conducted in the urban and suburban areas have been documented. Therefore, an addition of a study conducted in the setting of a rural health institution is necessary.
View Article and Find Full Text PDFBackground: Alzheimer's disease (AD) is a prevalent neurodegenerative condition characterized by progressive cognitive decline and memory impairment resulting from the degeneration and death of brain neurons. Acetylcholinesterase (AChE) inhibitors are used in primary pharmacotherapy for numerous neurodegenerative conditions, providing their capacity to modulate acetylcholine levels crucial for cognitive function. Recently, quinazoline derivatives have emerged as a compelling model for neurodegenerative disease treatment, showcasing promising pharmacological features.
View Article and Find Full Text PDFThe present investigation explored the growth performance, haematological parameters and serum biochemistry of flathead grey mullet under recirculating aquaculture system (RAS) and traditional culture systems. Nine hundred healthy fish, weighing 43.80 ± 3.
View Article and Find Full Text PDFThis paper evaluates the flowability and strength properties of alkali-activated mortar produced using silicomanganese fume (SiMnF) as the sole binder, combined with alkaline activators and sand, cured at room temperature (23 ± 1 °C). A total of 18 mixes were prepared by varying binder content (370, 470, and 570 kg/m), alkaline activator content (33, 43, and 53% of binder by weight), and NaOH concentration (8 M and 12 M). The SiMnF-based alkali-activated pastes were characterized using SEM, XRD, and FTIR techniques to study morphology, mineral composition, and functional groups, respectively.
View Article and Find Full Text PDFBackground: Methicillin-Resistant (MRSA) is both a human commensal and a pathogen that causes neonatal infection which is associated with significant morbidity and mortality. Its genetic flexibility and versatility have equipped it with the ability to develop resistance to numerous antibiotics. Outbreaks of infections in neonatal intensive care units as well as community infections have been reported mostly in developed countries.
View Article and Find Full Text PDFBackground: Acute coronary syndrome continues to be a significant cardiovascular issue. Statins are commonly acknowledged as medications that reduce LDL-C levels and stabilize plaques. Nevertheless, their efficacy is limited.
View Article and Find Full Text PDFTyphonium flagelliforme (T. flagelliforme) is an Indonesian rodent tuber plant traditionally used to treat cancer diseases. Although gamma-ray irradiation has been used to increase the content in the chemical compounds of the T.
View Article and Find Full Text PDFObjectives: Drug resistance in tuberculosis (TB) is a very important public health threat that should not be ignored. Understanding the gender, age, and characteristics of individuals affected by TB (without HIV, diabetes, or hepatitis B complications), particularly in terms of drug resistance or susceptibility, is crucial for effective prevention and management strategies, as most studies focus on TB/HIV co-infection.
Methods: A cross-sectional case study of age and gender was carried out in 140 individuals grouped into drug-resistant tuberculosis (DR-TB), drug-susceptible tuberculosis (DS-TB), and apparently healthy controls (AHCs).
Introduction: Cancers are a major cause of childhood mortality worldwide especially in LMICs where underdiagnoses and lack of quality cancer data hampers effective cancer control efforts. This study aimed to document and describe the patterns and characteristics of childhood cancers in the North East geopolitical zone of Nigeria.
Methods: This was a retrospective cross-sectional study that collected cancer data from 4 out of the 6 states in the North East of Nigeria.
Objective: The right internal mammary artery is considered to be the second choice for arterial conduits for coronary artery bypass grafting (CABG). However, the widespread use of bilateral internal mammary artery (BIMA) grafting is limited owing to increased technical demands, lengthy procedure, and high incidence of sternal wound complications. We compared the early clinical outcomes of a novel robot-assisted double-docking technique (DDT) with an open sternotomy technique for total arterial revascularization using BIMA.
View Article and Find Full Text PDFPotato (Solanum tuberosum L.) is the most widely grown vegetable in the world. Consumers and processors evaluate potatoes based on quality traits such as shape and skin color, making these traits important targets for breeders.
View Article and Find Full Text PDFIntroduction: Unmanned aerial vehicles (UAVs) are widely used in various computer vision applications, especially in intelligent traffic monitoring, as they are agile and simplify operations while boosting efficiency. However, automating these procedures is still a significant challenge due to the difficulty of extracting foreground (vehicle) information from complex traffic scenes.
Methods: This paper presents a unique method for autonomous vehicle surveillance that uses FCM to segment aerial images.
Background: Alzheimer's disease (AD) patients suffer from cognitive dysfunction. This study assessed the structural magnetic resonance imaging (MRI) scoring among Alzheimer's patients (age ≥18 years) to correlate with dementia severity according to mini-mental state exam (MMSE) scores.
Methods: This cross-sectional study evaluated Bangladeshi adult AD patients from January 2018 to December 2022 who attended with subjective memory complaints and fulfilled the diagnostic and statistical manual of mental disorders criteria (DSM 5) for diagnosing dementia.
Introduction: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a modern and minimally invasive technique to acquire diagnostic material from within the gastrointestinal tract, as well as from adjacent organs and structures, which can help in the diagnosis and staging of a variety of gastrointestinal malignancies, as well as for non-malignant conditions. Though well described in adults, there is limited literature on the diagnostic utility of EUS-FNA in paediatric patients. The objective of this study was to evaluate the diagnostic accuracy and clinical utility of EUS-FNA in paediatric patients performed at our centre over the last 17 years.
View Article and Find Full Text PDFBackground And Objectives: Stereotactic radiosurgery (SRS) with neoadjuvant embolization is a treatment strategy for brain arteriovenous malformations (AVMs), especially for those with large nidal volume or concomitant aneurysms. The aim of this study was to assess the effects of pre-SRS embolization in AVMs with an associated intracranial aneurysm (IA).
Methods: The International Radiosurgery Research Foundation AVM database from 1987 to 2018 was retrospectively reviewed.
Background: There are still many patients newly diagnosed with HIV at an advanced stage in Indonesia. We aimed to identify factors associated with 1-year mortality among cytomegalovirus (CMV)-infected people living with HIV (PLHIV).
Methods: This retrospective cohort study was carried out at a tertiary-care hospital in Jakarta, Indonesia (January 2017 to December 2022).