Publications by authors named "Yusuf Kucukbagriacik"
Breast cancer is a significant health problem worldwide, and the search for effective treatments is critical. Side effects of cancer treatments such as surgery, radiotherapy, and chemotherapy reduce the patient's standard of living. Recently, natural compounds from plants have gained attention as potential anticancer agents due to their safety, low toxicity, and potential efficacy.
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- The study investigates whether non-ionizing radiofrequency (RF) fields can trigger an adaptive response (AR) in adult mice and explores the molecular mechanisms behind this response.
- Conducted on 24 adult male Swiss-Albino mice, the experiment exposed two groups to 900 MHz GSM signals while two control groups were not exposed.
- Results indicated that increased reactive oxygen species (ROS) in the adaptive response group may have activated stress responses and influenced DNA repair gene expressions, while certain antioxidant levels decreased, suggesting complex interactions between RF exposure and cellular mechanisms.
In this study, it is aimed to investigate the effect of radiofrequency radiation (RFR) on apoptotic and antiapoptotic factors under different exposure conditions in human colonic adenocarcinoma cells (Caco-2). We analyzed the effects of 2.5 GHz continuous wave and 3 GPP modulated radiofrequency radiation exposure (15 min on, 15 min off) for 1 h and (1 h on, 1 h off) for 3 hours on Caco-2 cell lines.
View Article and Find Full Text PDFPurpose: Postoperative hypocalcemia is a frequently encountered complication of thyroid surgery. Since hypocalcemic symptoms are closely associated with sex, the aim of this study is to investigate the effects of sex steroids on muscle tissue under hypocalcemic conditions.
Methods: Six groups consisting of control male (M), control female (F), gonadectomized male (M-), gonadectomized female (F-), estradiol-applied gonadectomized male (MX), and testosterone-applied gonadectomized female (FX) rats were used.
Electrophysiology of papillary muscle in SAH: changes and N-acetylcysteine protection.
J Interv Card Electrophysiol
November 2009
Background: Although subarachnoid hemorrhage (SAH) serves as a good model to study heart-brain interactions, neither the changes on the single ventricular action potential (SVAP) and contraction nor the effects of possible cardioprotective agents have been investigated.
Materials And Methods: A total of 18 male rabbits were used for the three experimental groups. SAH was induced by replacing the cerebrospinal fluid (CSF) with fresh autologous blood at the ratio of 1 mL to the 1-kg body mass (N = 6).