RSNA 2023 Abdominal Trauma AI Challenge Review and Outcomes Analysis.

Purpose To evaluate the performance of the winning machine learning (ML) models from the 2023 RSNA Abdominal Trauma Detection Artificial Intelligence Challenge. Materials and Methods The competition was hosted on Kaggle and took place between July 26, 2023, to October 15, 2023. The multicenter competition dataset consisted of 4,274 abdominal trauma CT scans in which solid organs (liver, spleen and kidneys) were annotated as healthy, low-grade or high-grade injury.

Gold nanoparticles spectral CT imaging and limit of detectability in a new materials contrast-detail phantom.

This study involves the synthesis, characterization, and spectral photon counting CT (SPCCT) imaging of gold nanoparticles tailored for enhancing the contrast of small cancer lesions. We used the modified Turkevich method to produce thiol-capped gold nanoparticles (AuNPs) at different concentrations (20, 15, 10, 5, 2.5, 1.

ABO Blood Group Genotypes and Demographic Traits in Susceptibility to Type 1 Diabetes Mellitus in Lagos, Southwest, Nigeria.

Studies have shown that ABO blood groups and demographic traits influence susceptibility to type 1 diabetes mellitus (T1DM) and can be used in combination with insulin therapy to reduce the disease's burden. However, geographical variations exist in the influence of demographic traits and ABO blood groups on susceptibility to diseases and thus require establishing it in every locality. This study determined the influence of demographic traits and ABO blood groups on the prevalence of T1DM in Lagos, Nigeria.

Detection of clinically relevant antibiotic-resistant bacteria in shared fomites, waste water and municipal solid wastes disposed near residential areas of a Nigerian city.

Studies investigating environmental hotspots of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in Nigeria are limited. This study was designed to assess various environmental sources and commonly touched surfaces as potential carriers of ARB and ARGs with implications for public health. A total of 392 samples, including sewage (36), sludge (36), diapers (20), plastics (20), water sachet polythene bags (20), food wastes (20), soil beneath dump sites (20), and frequently touched surfaces such as restroom floors (80), corridors (24), door handles (56), and room floors and walls (60), were collected and screened for the presence of resistant bacteria carrying genes such as , , , , and .

Assessing the impact of COVID-19 on prescription patterns and antibiotic use: Insights from three military health facilities.

Background: The COVID-19 pandemic disrupted health systems globally and there are suggestions it impacted antibiotics prescribing patterns in clinical practice.

Objectives: This study aimed to assess the effects of the COVID-19 pandemic on the prescribing patterns in three Nigerian military health facilities and investigate the factors associated with antibiotic prescriptions.

Methods: This was a two-year cross-sectional retrospective study.

Twenty-Four-Hour Intraocular Pressure Pattern In Glaucoma Suspects in an African Population.

Prcis: Twenty-four-hour intraocular pressure measurement (Phasing) among glaucoma suspects showed higher intraocular pressure (IOP), greater fluctuation, and more varying peak times occurring mostly outside clinic hours, between 12 midnight and 8 am in 68.9% of them.

Purpose: To characterise 24-hour variation in IOP, in glaucoma suspects and normal individuals in an African population.

Crustal structure and seismic anisotropy of rift basins in Somaliland.

Rift margins provide insights into the processes governing the rupture of the continental lithosphere and the subsequence formation of sedimentary basins. The Proterozoic basement underlying Somaliland has been affected by multiple rifting; however, the crustal structure of these rifted basins remains unknown. This study utilized teleseismic receiver function analysis, Bayesian inversion, common conversion point imaging and 2D forward gravity modelling to examine the crust and upper mantle of Somaliland.

Joint pain, physical function, and balance self-confidence in acromegaly versus nonfunctioning pituitary adenoma patients.

Context: Patients with acromegaly (PWA) experience balance issues, despite achieving biochemical remission, that may significantly impair their quality of life.

Objective: We sought to assess the prevalence of falls and balance self-confidence in PWA in comparison with a control group. Furthermore, we investigated the effect of joint pain and function as predictors for their balance self-confidence.

Bioremediation of Cu and Zn by guinea fowl feather wastes and biodegradation of Cu- and Zn-polluted feathers by free and immobilized heavy-metal-tolerant bacterium sp. IY-BUK1.

One of the major pollutants generated from guinea fowl farms and slaughterhouses is guinea fowl feather (GFF) wastes. Chicken feathers are an important substrate for removing aqueous pollutants due to their structural characteristics, but the application of GFFs for such purposes has not been elucidated. This study was carried out to determine the potential of raw as well as chemically and physically pretreated GFFs in the bioremediation of copper (Cu) and zinc (Zn) from aqueous solutions and the subsequent biodegradation of Cu- and Zn-laden GFFs using free and immobilized heavy-metal-tolerant bacteria.

Community Eye Care Outreaches through Collaborations with Community-Based Organisations in Resource-Poor Settings in Ilorin, Nigeria.

Background: The access to universal eye health is still poor in many developing countries. There are various initiatives to address this problem, but the initiatives are majorly under the support of external funding. This study reports community outreaches supported by community-based organisations over a 7-year period in resource-poor settings in Ilorin, Kwara State, Nigeria.

Exploring NFB pathway as a potent strategy to mitigate COVID-19 severe morbidity and mortality.

The pandemic of coronavirus disease 2019 (COVID-19), for which there does not appear to be an approved cure, the primary treatment options consist of non-pharmacological preventive measures and supportive treatment that are aimed at halting the progression of the disease. Nuclear factor kappa B (NFkB) presents a promising therapeutic opportunity to mitigate COVID-19-induced cytokine storm and reduce the risk of severe morbidity and mortality resulting from the disease. However, the effective clinical application of NFkB modulators in COVID-19 is hampered by a number of factors that must be taken into consideration.

Extraskeletal Osteosarcoma: A Case Report.

Extraskeletal osteosarcoma (ESO) is a rare form of osteosarcoma that has no attachment to bone and can be found in the thigh, retroperitoneum, chest, breast, orbit, retropharyngeal space etc. Literature about ESO is still mainly case reports and case series with few reported cases in our environment. We therefore report this 52-year-old with swelling at the left shoulder which progressed over a 3-year period.

Cross-sectional survey of knowledge and attitudes of healthcare workers and community members toward the Ebola virus disease and antimicrobial resistance pathogens outbreaks in Nigeria.

Introduction: the 2014 Ebola virus disease (EVD) outbreak in Nigeria has further raised the awareness of health-care workers (HCWs) and community members (MCs) on the threat posed by infectious diseases and the need for improvement on infection control practices. However, awareness of dangers of increasing incidences of antimicrobial resistance (AMR) in hospitals and communities remained low.

Methods: a cross-sectional survey of awareness of 195 HCWs and 265 MCs toward EVD and AMR was conducted through a structured questionnaire.

Case series of retinopathy of prematurity blindness in Nigeria: A wakeup call to policy makers, hospitals, ophthalmologists and paediatricians.

Background Statement: Inadequate retinopathy of prematurity (ROP) screening coverage portends a high risk for increasing the cases of ROP blindness. This study aims to report the clinical profile of pre-term babies who developed ROP blindness, highlight the usefulness in determining screening criteria and the role of private hospitals in ROP blindness prevention.

Case Series Report: Online Google form and telephone survey was conducted from May to December 2020 among paediatric ophthalmologists who provided the clinical details of ROP blind children seen between 2016 and 2020.

Gaps in the implementation of COVID-19 mitigation measures could lead to development of new strains of antimicrobial resistant pathogens: Nigerian perspective.

The severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is a new virus that is responsible for COVID-19, a disease that complicate health conditions and results in death. The total diversion of attention of government and health care workers (HCWs) to prevent the escalation of the pandemic disease has placed a great barrier to diagnosis and treatment of other illnesses that share common symptoms with COVID-19, and that has consequently enabled the endemic practice of self-antimicrobial medication to increase in Nigeria. Development of secondary infections in COVID-19 and in other conditions, caused by antibiotic resistant pathogens could make them more deadly now or in the future.

Cervical cytopathological changes in pregnancy: An experience from a low resource setting.

Background: Cervical cancer is the leading cause of death among women in developing countries. It is preventable through effective cervical cancer screening program. However, in Nigeria, screening programs are opportunistic and coverage is insufficient to make an impact.

Is Preptin a New Bone Metabolism Parameter in Hemodialysis Patients?

Background: Preptin is a bone-anabolic pancreatic peptide hormone. Its role in bone metabolism has been studied in rats and in patients with diabetes, but its levels and significance in bone metabolism in hemodialyzed (HD) patients is unknown.

Methods: The relationships between preptin and anthropometric and biochemical parameters related to bone metabolism were studied in 73 patients on chronic hemodialysis (48 males, 25 females; mean age of 57 years; HD vintage of 69.

Clinical, endoscopic and histological profile of colorectal cancers seen on colonoscopy in Kano, North-Western Nigeria.

Background: Colorectal cancer (CRC) is the most prevalent gastrointestinal (GI) cancer. With 5% risk of developing CRC in life, it became the third leading cause of cancer death in developed nations. In Nigeria, it is the most common GI cancer.

A mathematical model of Coronavirus Disease (COVID-19) containing asymptomatic and symptomatic classes.

The research work in this paper attempts to describe the outbreak of Coronavirus Disease 2019 (COVID-19) with the help of a mathematical model using both the Ordinary Differential Equation (ODE) and Fractional Differential Equation. The spread of the disease has been on the increase across the globe for some time with no end in sight. The research used the data of COVID-19 cases in Nigeria for the numerical simulation which has been fitted to the model.

Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective.

The disease caused by viral pneumonia called severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) declared by the World Health Organization is a global pandemic that the world has witnessed since the last Ebola epidemic, SARS and MERS viruses. Many chemical compounds with antiviral activity are currently undergoing clinical investigation in order to find treatments for SARS-CoV-2 infected patients. On-going drug-drug interaction examinations on new, existing, and repurposed antiviral drugs are yet to provide adequate safety, toxicological, and effective monitoring protocols.

Opioid Use in Athletes: A Systematic Review.

Context: The opioid epidemic has been well-documented in the general population, but the literature pertaining to opioid use and misuse in the athletic population remains limited.

Objectives: The objectives of this study were to seek answers to the following questions: (1) what are the rates of opioid use and misuse among athletes, (2) do these rates differ compared with the nonathletic population, and (3) are there specific subgroups of the athletic population (eg, based on sport, level of play) who may be at higher risk?

Data Sources: The Embase, MEDLINE, and PubMed were used for the literature search.

Study Selection: Records were screened in duplicate for studies reporting rates of opioid use among athletes.

Academic Implications of Uncorrected Refractive Error: A Study of Sokoto Metropolitan Schoolchildren.

Background: The Sustainable Development Goal 4 ensures that all children have an inclusive and equitable quality education. However, uncorrected refractive errors (UREs) have been a major cause of limitations with regard to quality education as vision plays a vital role in child learning and development. Thus, any problem affecting the child's vision could adversely affect the quality of the child's education.