Publications by authors named "Yusuf Curek"

Background And Study Aim: We evaluated exocrine pancreas functions using a noninvasive indicator in a case-control study conducted on children and adolescents diagnosed with type 1 diabetes mellitus.

Patients And Methods: Sixty-seven patients who participated in a summer camp were enrolled in this study. Nineteen healthy children in the same age group were assigned to the control group.

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Objective: Iodine deficiency (ID) continues to be a problem around the world. This study investigated the prevalence of ID and goiter among school-age children in the city center of Antalya, Turkey. The aim was to investigate the effect of an iodization program, which had been running for sixteen years, on nutritional iodine status in this population.

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Article Synopsis
  • Non-syndromic monogenic obesity is a rare genetic cause of severe obesity in children that can be difficult to identify without genetic testing, especially if there are no obvious physical symptoms.
  • This study involved screening 105 children with severe obesity (obesity starting before age 7) for mutations in 41 genes linked to obesity, using advanced DNA sequencing methods.
  • The results revealed six new and four previously known genetic variants associated with obesity in 11 children, indicating a 10.4% prevalence of monogenic obesity in the group studied.
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Objective: Childhood obesity (OB) is an acknowledged global problem with increasing prevalence reported around the world. We conducted this study with the aim of determining the local trend in OB and overweight (OW) prevalence in the last decade and to observe the alteration of OB and OW prevalence by age group. An additional aim was to construct new age- and gender-specific body mass index (BMI) reference percentile charts for Turkish children living in the city center of Antalya.

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Article Synopsis
  • - Wolfram syndrome (WS) is a rare genetic disorder marked by diverse symptoms like diabetes insipidus, diabetes mellitus, optic atrophy, and hearing loss, caused by mutations in a specific gene.
  • - This study examined three patients from unrelated Turkish families, revealing a variety of symptoms and ages of onset; for instance, two patients showed symptoms in childhood, while one presented with cataracts and diabetes as the initial symptoms.
  • - Genetic analysis identified previously known mutations and a new variant in the WFS1 gene, highlighting the need for genetic testing to confirm WS diagnosis, especially in cases of non-autoimmune insulin-dependent diabetes.
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