Publications by authors named "Yuspian Nur"
Background: Biomarkers are essential tools for diagnosing diseases. Saliva, as a human fluid, effectively reflects the body's condition due to its rich composition. Analyzing saliva components allows for noninvasive, cost-effective, and time-efficient screening and diagnosis.
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- Chronic myeloid leukaemia (CML) is a serious type of leukaemia that requires effective diagnostic methods, including the use of electrochemical biosensors with aptamers for early detection.
- In the study, researchers used a KK1D04 aptamer on a screen-printed carbon electrode (SPCE) enhanced by CeO nanoparticles to identify K562 CML cells, optimizing various parameters for better sensor performance.
- The resulting aptasensor achieved a limit of detection of 16 cells/mL and showed specificity for K562 cells over other cell lines, suggesting it could be useful for point-of-care testing for CML.