Publications by authors named "Yushu Xing"

Chromobox protein homolog 2 (CBX2) exerts a multifaceted impact on the progression of aggressive cancers. The proteasome-dependent pathway is crucial for modulating CBX2 regulation, while the specific regulatory roles and mechanisms of deubiquitinating enzymes targeting CBX2 remain poorly understood. Mass spectrometry analysis identified ubiquitin-specific peptidase 27X (USP27X) as a deubiquitinating enzyme that targets CBX2.

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Article Synopsis
  • Platycodon grandiflorus is a traditional Chinese medicinal plant known for its expectorant and anti-inflammatory properties, but its cultivation is challenged by soil salinity.
  • In response to salt stress, the study identified nearly 9,000 differentially expressed genes and 428 altered metabolites, primarily affecting the L-phenylalanine metabolic pathway and increasing the production of lignin and triterpene saponins like Platycodin D.
  • The findings indicate that while salt stress reduces plant biomass and disrupts antioxidant activities, it simultaneously triggers adaptive responses that enhance certain beneficial compound levels in P. grandiflorus.
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In order to demonstrate the relationship between methylation of fragile histidine triad (FHIT) and T-cadherin/H-cadherin (CDH13) genes and liver cancer, the methylation status of FHIT and CDH13 was detected in healthy individuals and in Mongolian and Han patients with liver cancer. The phenol-chloroform method was used to extract genomic DNA. The methylation specific polymerase chain reaction method was applied to detect the methylation status of FHIT and CDH13.

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Objective: To study transdermal absorption characteristics of eugenol in compound Nanxing pain-relieving cataplasm, and discuss the effect of gaultherolin on the transdermal absorption of the cataplasm.

Method: The improved franz diffusing cell was adopted with hairless mice skins as transdermal carriers. The content of eugenol in receptor liquid, skins and cataplasm were analyzed by HPLC and compared with the cataplasm without gaultherolin.

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