Publications by authors named "Yushan Fan"

Objective: Gastroparesis is one of the complications of diabetes mellitus, which has a major impact on the quality of life of patients, and the limited therapeutic options currently available make it a public health problem. No bibliometric studies on diabetic gastroparesis have been published to date. Therefore, the aim of this paper is to summarize and analyze the research hotspots for researchers.

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Article Synopsis
  • This study investigates the acupoint selection rules for treating metabolic-associated fatty liver disease (MAFLD) using acupuncture and moxibustion through data mining techniques.
  • Researchers reviewed over 178 clinical studies to create a database of 130 acupoints, highlighting the frequency and specific locations of their use, primarily in the lower limbs and abdomen.
  • The findings reveal five key acupoints and their top combinations, with significant patterns in how these points are clustered and related to MAFLD treatment.
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Background: Carpal tunnel syndrome (CTS) is the most prevalent upper limb compressive neuropathy. A considerable number of clinical trials and meta-analyses have provided evidence supporting the effectiveness of acupuncture in treating CTS. Nevertheless, the ideal choice of acupoints remains ambiguous.

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Background: Acupuncture is widely used in the treatment of tinnitus worldwide because of its good efficacy and safety. However, the criteria for selecting acupoint prescriptions and combinations have not been summarized. Therefore, data mining was used herein to determine the treatment principles and the most effective acupoint selection for the treatment of idiopathic tinnitus.

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Objectives: To explore the rules of acupoint selection in the treatment of neurogenic bladder (NB) with acupuncture and moxibustion by using data mining.

Methods: The clinical research literatures on acupuncture treatment of NB were collected from PubMed, Embase, Cochrane Library, CNKI, Wanfang Database, VIP Database and China Biology Medicine from retrieved to January 1, 2023. The acupoint prescription database was established using Excel 2019.

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Postherpetic neuralgia (PHN) represents a notable clinical challenge as it is the most prevalent and severe complication of herpes zoster (HZ). The primary objective was to investigate the current research status and hotspots of PHN research during the period from 2000 to 2022. The literature pertaining to PHN was gathered through the utilization of the Web of Science Core Collection, spanning from January 2000 to December 2022.

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Background: Piriformis syndrome (PS) is a neuromuscular condition characterized by discomfort in the gluteal region. The efficacy of acupuncture as a treatment modality for PS has been substantiated through a multitude of clinical trials. However, certain queries persist, such as the optimal approach for identifying the most efficacious acupoints.

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Non-destructive and interference-free monitoring of pesticide residue on the surface of fruits is still a challenge. Herein, a SERS aptasensor based on a flexible substrate was established for effective carbendazim (CBZ) detection on apple peel. In this sensor, electrospun PVDF/CQDs film served as a flexible supporting substrate.

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Background: Piriformis syndrome (PS) is a common disease that is difficult to clinically treat, which seriously affects people's health and living quality. Multiple clinical studies have demonstrated that acupuncture therapy is an effective treatment for PS, but the optimal method of various acupuncture methods has remained unknown. The aim of this study protocol is to compare the efficacy and the safety of different acupuncture methods for PS.

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Background: Carpal tunnel syndrome (CTS), as the most common compression neuropathy in the upper limb, can lead to upper limb dysfunction in patients. The effectiveness of acupuncture in treating CTS has been validated based on numerous clinical trials and meta-analyses, but questions remain, such as how to select the best acupoints. Our purpose is to conduct the first data mining analysis to identify the most effective acupoint selection and combinations for treating CTS.

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Hydroxy-α-sanshool (α-SOH) is the principal ingredient responsible for the numbing sensation in spicy hotpot. However, utilizing surface-enhanced Raman scattering (SERS) to analyze the α-SOH in hotpot seasoning is challenging due to the significant interference of capsaicin (CAP). Therefore, two schemes were proposed to address CAP interference in hotpot seasoning, namely laccase-catalyzed conversion and metal-organic framework (MOF) interaction.

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Objective: To evaluate the efficacy and safety of moxibustion at Baihui (CV20) combined with acupuncture in treatment of cervical vertigo.

Methods: From the databases, such as CNKI, VIP, WanFang, CBM, PubMed, Cochrane Library and Embase, the studies of randomized controlled trials (RCTs) on moxibustion at CV20 combined with acupuncture for cervical vertigo were searched from inception to September 15, 2021. The Cochrane risk of bias assessment tool was utilized to evaluate the quality of the included literature.

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Residues of organophosphorus pesticides (OPs) raise considerable concern, while identifying OPs from unknown sources is still a challenge to onsite fluorescence techniques. Herein, a dual-emission-capture sensor module, based on a TPB-DMTP@S-CDs/MnO fluorescence composite, is developed for OP fingerprint recognition. TPB-DMTP@S-CDs/MnO, synthesized by a hydrothermal method and self-assembly, is spectrographically validated as a dual-wavelength fluorescence source.

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Objective: To observe the effect of electroacupuncture (EA) combined with Zhuang-medicine-thread moxibustion on expression of apoptosis-related factors in gastric antrum of diabetic gastroparesis (DGP) rats, so as to explore its mechanism underlying improvement of DGP.

Methods: Male SD rats were randomly divided into normal, model, medication, EA, Zhuang-medicine-thread moxibustion (moxibustion) and EA+moxibustion (combination) groups (12 rats in each group). The DGP model was established by intraperitoneal injection of streptozotocin (STZ).

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Objective: To observe the effect of electroacupuncture (EA) combined with Zhuang-medicine-thread moxibustion on oxidative stress-related indicators in diabetic gastroparesis (DGP) rats, so as to explore its mechanism underlying improvement of DGP.

Methods: Male SD rats were randomly divided into normal, model, medication, EA, Zhuang-medicine-thread moxibustion (moxibustion) and EA+Zhuang-medicine-thread moxibustion (combination) groups (15 rats in each group). The DGP model was established by intraperitoneal injection of streptozotocin (STZ).

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An enzyme-regulated UiO-66-NH/MnO fluorescence sensor, fully functionalized with spectrometric capacities, is developed for budget-friendly total organophosphorus pesticides (OPs) determination. The fluorescence probe, UiO-66-NH/MnO, is hydrothermally synthesized and morphologically examined. A specialized enzyme-catalyzed reaction, which can be gradually inhibited by OPs, is designed with participations of alkaline phosphatase (ALP) and sodium L-ascorbyl-2-phosphate (AAP).

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Objective: To observe the effect of ZhuLian's type Ⅱ inhibition needling technique on sex hormones, insulin resistance and ovarian morphology in rats with polycystic ovary syndrome (PCOS), so as to explore its mechanism on regulating endocrine and metabolic dysfunction of PCOS.

Methods: Twenty-four female SD rats were randomly divided into control, model and ZhuLian acupuncture groups (=8 in each group). The PCOS model was established by continuous gavage of letrozole combined with high-fat diet.

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Objective: To observe the efficacy of inhibition type Ⅰ acupuncture for acne with spleen-stomach dampness-heat, and to explore its possible action mechanism.

Methods: A total of 82 patients of acne with spleen-stomach dampness-heat were randomly divided into an observation group and a control group, 41 cases in each group. The patients in the control group were treated with capsules (1 g, 3 times per day) and 0.

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Objective: To observe the effect of electroacupuncture (EA) combined with Zhuang-medicine-thread moxibustion on silent information regulator-1 (SIRT1)/nuclear factor kappa B (NF-κB) signal pathway and inflammatory factor expression in gastric antrum tissue of diabetic gastroparesis (DGP) rats, so as to explore its mechanism underlying improvement of DGP.

Methods: Male SD rats were randomly divided into normal, model, medication, EA, Zhuang-medicine-thread moxibustion (moxibustion) and EA+moxibustion groups (=12 per group). The DGP model was established by intraperitoneal injection of streptozotocin (STZ).

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The specific expression profile and function of circular RNAs (circRNAs) in mammalian ovarian follicles, especially during the atresia process, are unclear. In this study, we verified and explored the expression and function of circ-ANKHD1 in granulosa cells. Our results showed that abundance of circ-ANKHD1 was significantly lower in the granulosa cells than that of ANKHD1.

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Objective: To observe the clinical efficacy of 's type-Ⅰ inhibition acupuncture combined with medicinal thread moxibustion for acute herpes zoster (HZ), and explore the possible analgesic mechanism.

Methods: Sixty-six patients with acute HZ were randomly divided into an observation group (33 cases, 1 case dropped off) and a control group (33 cases, 1 case dropped off). The patients in the control group were treated with valaciclovir hydrochloride tablets, mecobalamin tablets and vitamin B tablets for 14 days.

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Background: Nocturia is a common and highly troubled lower urinary tract symptom, which has a wide range of effects. About 33% of patients with lower urinary tract symptoms have been affected by nocturia. Nocturia is mainly manifested as the increase of urination frequency and urine volume at night.

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Article Synopsis
  • Acupoints are defined as areas where structure and function combine, serving as energy aggregation and release points.
  • The paper explores acupoints through the lens of energetics, highlighting how acupuncture involves applying energy to these specific points.
  • Key factors influencing the function of acupoints include variations in speed, direction, time, and local temperature.
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The proteins in the seminal plasma and on the sperm surface play important roles in sperm function and numerous reproductive processes. The cysteine-rich secretory proteins (CRISPs) are enriched biasedly in the male reproductive tract of mammals, and CRISP2 is the sole member of CRISPs produced during spermatogenesis; whereas the role of CRISP2 in fertilization and its association with fertility of boars are still unclear. This study aimed to investigate the relationship between the sperm CRISP2 and boar fertility, and explore its impact sperm fertilizing ability.

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Binding-fixation is the most commonly used method for acupuncture research in rats, but its resulted stronger stress response may affect the experimental outcomes. Hence, we developed a practical fixing device using the abandoned meshy cage covers, bolts, hooks, and loop fasteners. It includes two straps, two ropes, a small jacket with a self-locking Velcro strap and a meshy cage cover with a piece of fixed Velcro which may be placed on a rectangular storage box.

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